Biomedical subjects

K Gallouj

Publications and source records attributed to K Gallouj.

2 recordsLinked to original sources

PubMed1999

[Interstitial lung disease induced by timolol eye solution].

Timolol maleate is a beta-blocker widely used in topical administration for open angle glaucoma. We report a case of interstitial pneumopathy which developed in a 58-year-old patient who was given timolol eyedrops (2 drops b.i.d. since 1986). The patient presented with cough and dyspnea and was found to have a restrictive disorder leading to hypoxemia (68 mmHg at rest and 51 mmHg during exercise). Bronchial lavage fluid had high lymphocyte (28%) and neutrophil (7%) counts. Transbronchial biopsies demonstrated moderate fibrous thickening of the interalveolar walls. Timolol eyedrops were stopped. Three months later, the patient was asymptomatic with normal lung function, chest x-ray and thoracic CT-scan.

Adrenergic beta-Antagonists↗

PubMed1999

[Pulmonary hemorrhagic syndrome after inhalation of cocaine].

Frequency of recreational abuse of cocaine is increasing. We report the case of a patient who developed an acute anemia associated with an alveolar hemorrhage after repeated inhalation of cocaine. He presented with daily hemoptysis and dyspnea. Chest-X ray and CT scan showed bilateral micronodular opacities. The fibroscopic alveolar lavage fluid showed fresh blood. DLCO/VA was 117% predicted. With oxygen therapy and no blood transfusion the evolution was positive within 48 hours, without relapse. The occurrence of hemoptysis in subjects who inhale cocaine must lead to suspect cocaine induced-pulmonary hemorrhage.

Adolescent↗