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Biomedical subjects

K Glas

Publications and source records attributed to K Glas.

At least 19 recordsLinked to original sources
PubMed2003

[Osteoporosis in inflammatory bowel disease - results of a survey among members of the German Crohn's and Ulcerative Colitis Association].

INTRODUCTION: Osteoporosis is a frequent and clinically important complication in inflammatory bowel disease (IBD). Prevalence and risk factors have been examined in small numbers of patients. With a nationwide survey of members of the German Crohn's and Ulcerative Colitis Association (DCCV) we wanted to evaluate the situation in a larger group of patients. METHODS: Questionnaires were sent with the autumn issue of the members journal to approx. 14,620 affected members of the DCCV. Items covered osteoporosis, clinical symptoms, anamnesis and sociodemographic topics. Results are presented as descriptive analysis and in a logistic regression analysis of factors contributing to the osteoporosis risk. RESULTS: 2,536 questionnaires could be used (17.3 %). Mean age and distribution concerning diagnosis and gender were comparable to the DCCV members in total. The prevalence of pathologic bone density was 62.3 % in those 1,265 patients (50.1 %) who underwent bone densitometry in the course of their disease. The analysis led to the following possible risk factors: disease activity (high chronic activity or more than 1 acute flare annually vs. remission, p < 0.001), lifetime steroid dosage > 10 g (p = 0.002), Crohn's disease vs. ulcerative colitis (p = 0.02), multiple bowel resection (p = 0.032), age (p = 0.018) and low body mass index (p = 0.034). 83.4 % of the patients with pathologic bone density received specific therapy, but most of those (63.5 %) were solely substituted with calcium and vitamin D. CONCLUSION: This is the first study looking at epidemiology and risk factors of osteoporosis in a large study population of patients with inflammatory bowel disease. Although the prevalence may be overestimated due to selection bias in our study, osteoporosis is confirmed as a frequent and clinically relevant complication in IBD. Bone densitometry is recommended in those patients with one or more risk factors.

Adolescent↗
PubMed1994

[Teleradiology with personal computers].

A system to transmit radiographic images with the aid of a personal computer (PC) via phone line is presented. The pictures are recorded by a camcorder and digitized by the PC. They are sent to the receiver by a modem via phone line. The different steps can be programmed. MR and CT pictures as well as ordinary x-ray pictures have been transmitted. It takes about 45 s to send a picture. It arrives in good quality, and findings are clearly represented. After the sending process is completed, all pictures can be reviewed in seconds. The presented system is interesting for its low price when a PC is available.

Computer Communication Networks↗
PubMed1982

Long-term follow-up results of 97 finger replantations.

From a total number of 664 finger replantations (DII-DV) we were able to carry out a follow-up of 97 postoperative cases using the follo-wing assessment criteria: mobility, sensitivity, type of amputation, mechanism of injury, level and extent of amputation. Subjective criteria were also taken into account. Using the results of the study we have been able to formulate an evaluation as to the absolute indication for operation of fingers DII-DV.

Amputation, Traumatic↗
PubMed1982

Replantation of the hallux by microsurgical techniques.

In this report three cases of successful hallux replantation are presented. The indications for this type or surgery are discussed on the basis of the functional results of these replantations. In our opinion, corrective surgery is indicated in all cases of traumatic hallux and/or multiple-toe amputations.

Adult↗
PubMed1981

[Activity of plasminogen activators and plasmin inhibitors in the joint capsule in various articular diseases (author's transl)].

The activity of plasminogen activators and plasmin inhibitors in articular capsules of the hip and knee joints in rheumatoid arthritis, chronic traumatic inflammation, arthrosis and aseptic loosening of prosthesis was determined histochemically and correlated with the degree of mobility in osteoarthrosis of the hip. Microscopically unchanged articular capsules were employed as reference sites. In inflammatory articular diseases the plasminogen activator activity was significantly reduced, whereas it remained unchanged in arthrosis and necrosis of the heas of the femur, and significantly enhanced in aseptic loosening of prosthesis. Plasmin inhibitor activity was established in joint capsules with inflammatory changes only; in case of rheumatic inflammation, it was higher than with traumatic inflammation. In osteoarthrosis of the hip there is a positive correlation between joint mobility and plasminogen activator activity. The results point towards involvement of the local fibrinolytic system in joint diseases; however, no definite statement can be made with regard to possible causative linkups.

Arthritis, Rheumatoid↗
PubMed1978

[The fixed lumbar lordosis due to slipped disks].

The fixed lumbar lordosis is represented by a group of characteristic symptomes; they specifically happen to the LWS of adolescents which are in a specific pathogenic situation. The cause of the fixed lumbar lordosis is almost a slipped discus. The case of an adolescent is presented, who had two operations because of twice slipped discus in one year.

Adolescent↗