[Case of primary meningeal sarcoma with extracranial metastases].
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Biomedical subjects
Publications and source records attributed to K Guzowski.
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The authors observed a case with favourable outcome in which besides the axial signs of Opalski syndrome crossed paresis of extremities and bladder disturbances were present. The substrate of clinical manifestations was a submedullary focus spreading to invole pyramid decussation.
In 2 daughters of healthy parents severe myasthenia with involvement of the eye muscles, bulbar muscles and extremities developed at the age of 20 and 28 years. In both patients persistent thymus was demonstrated. The authors suggest that familial occurrence of myasthenia does not seem to be coincidental; there may be a relationship with genetically determined HL-A system.
On the basis of a study of 218 control subjects in 10-year age groups the authors determined the mean levels and critical values of certain serum lipid components (cholesterol, triglycerides, beta-lipoproteins, esterified fatty acids and total lipids). Forty-two subjects were isolated (11.2%) with hyperlipoproteinaemia. Other atherosclerosis risk factors were determined in them as well. Hypertension was found in 19%, diabetes in 7%, obesity in 14%, smoking in 43%. The authors discuss the criteria qualifying the patients to the control group in the studies on lipid metabolism.
In 195 patients with strokes the authors determined in the fourth week of the disease the levels of cholesterol, total lipids, beta-lipoproteins, esterified fatty acids and triglycerides. This study demonstrated that the group of strokes was not homogeneous. Lipid metabolism disturbances were found in 52% of the patients, and in 48% the values of lipids were normal, that is below the critical level. The greatest lipid metabolism changes were observed in 65 patients (33%), and in this group the level of at least one of the determined lipids exceeded greatly the critical value. The authors believe that this group comprised subjects with primary or secondary hyperlipidaemia (according to the criteria of Fredricksen). Analysing the group of strokes as a whole (patients with and without lipid metabolism disturbances) it was demonstrated that the greatest number of patients had raised cholesterol level - 34%, followed by total lipid level - 31%, triglyceride level - 27%, esterified fatty acids - 24%, beta-lipoproteins - 21%.