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Biomedical subjects

K H Abd-el-Maeboud

Publications and source records attributed to K H Abd-el-Maeboud.

5 recordsLinked to original sources
PubMed1998

An increased number of replaced embryos counteracts the adverse effect of hydrosalpinges on IVF/ET outcome.

PURPOSE: The relationship between the number of replaced embryos and the outcome of IVF-ET in patients with hydrosalpinges was investigated in a retrospective, nonrandomized study performed at a governmental IVF center. METHODS: One hundred patients undergoing 161 IVF cycles ending in embryo transfer were studied. Previously diagnosed hydrosalpinges were evident on transvaginal sonography in 48 cycles in 26 patients (group I) and not evident in 15 cycles in 10 patients (group II). The control group included 98 cycles in 64 patients with tubal lesions other than hydrosalpinx. Pregnancy and implantation rates were the main outcome measures. RESULTS: Replacement of three or fewer embryos was associated with significantly lower implantation rates in group I compared to controls. Despite the difference in the rank of IVF trial within the same group, significantly lower implantation rates were found when four or fewer embryos were replaced in the control group and not in group I. CONCLUSION: An increased number of replaced embryos counteracts the adverse effect of hydrosalpinges on IVF/ ET outcome.

Adult↗
PubMed1997

Hydatid cyst of Morgagni: any impact on fertility?

On laparoscopy in 3 patients with primary infertility, the only pathology found was hydatid cysts of Morgagni that were excised. In one patient with monolateral hydatid cyst, pregnancy failed to be achieved. Despite prior failure of repeated trials of ovulation induction and intrauterine insemination in the other 2 patients, a spontaneous pregnancy was achieved within 2-3 months following laparoscopic extirpation of hydatid cysts of Morgagni. The hydatid cysts were bilateral in one case; and monolateral (in relation to the only present tube with a unicornuate uterus) in the other case. It is concluded that hydatids of Morgagni, as a single pelvic pathology, might hinder fertility. Laparoscopic extirpation of these cysts would improve ovum pick-up and enhance fertility.

Adult↗
PubMed1997

Altered endometrial progesterone/oestrogen receptor ratio in luteal phase defect.

The total oestrogen and progesterone receptor levels (TER, TPR) were measured in endometrial biopsy samples of 10 infertile patients with luteal phase defect (LPD) and compared to those of controls. Serum levels of progesterone (P), obtained in the luteal phase, were also measured. Midluteal phase P values were significantly decreased in LPD cycles; however some overlap of values existed. LPD cycles had significantly lower endometrial TER and TPR concentrations than did control cycles. TPR/TER ratio was found to be a reliable test for diagnosis; having a sensitivity, and specificity of 90% and the odds ratio of 81. The TPR/TER ratio for inphase endometria ranged between 1.13 and 58.22, with 95% confidence. It seems that abnormal folliculogenesis, as a cause of LPD, results in wide ranges of endometrial TER and TPR concentrations, yet with well defined alteration in TPR/TER ratio. Summation of the results of the present study along with those previously reported, indicates that TPR/TER ratio may be of great value in characterisation of a well defined endometrial receptor imbalance in luteal phase defect, whatever the underlying aetiology.

Adult↗
PubMed1991

Rectal suppository: commonsense and mode of insertion.

Rectal suppository is a well-known form of medication and its use is increasing. The commonest shape is one with an apex (pointed end) tapering to a base (blunt end). Because of a general lack of information about mode of insertion, we asked 360 lay subjects (Egyptians and non-Egyptians) and 260 medical personnel (physicians, pharmacists, and nurses) by questionnaire which end they inserted foremost. Apart from 2 individuals, all subjects suggested insertion with the apex foremost. Commonsense was the most frequent basis for this practice (86.9% of lay subjects and 84.6% of medical personnel) followed by information from a relative, a friend, or medical personnel, or from study at medical school. Suppository insertion with the base or apex foremost was compared in 100 subjects (60 adults, 40 infants and children). Retention with the former method was more easily achieved in 98% of the cases, with no need to introduce a finger in the anal canal (1% vs 83%), and lower expulsion rate (0% vs 3%). The designer of the "torpedo-shaped" suppository suggested its insertion with apex foremost. Our data suggest that a suppository is better inserted with the base foremost. Reversed vermicular contractions or pressure gradient of the anal canal might press it inwards.

Adult↗