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K H Chance

Publications and source records attributed to K H Chance.

3 recordsLinked to original sources
PubMed1988

Effect of blood sampling site on measurements of bilirubin-albumin binding.

Significant arterio-venous concentration gradients in metabolites such as lactate could result in sampling site differences in bilirubin binding measurements. Therefore, total bilirubin and apparent unbound bilirubin concentrations were determined on paired capillary and arterial serum samples from ten neonates with hyaline membrane disease. There were no significant arterial versus capillary differences in bilirubin binding in these infants. However, a small, statistically significant but clinically irrelevant, difference in total bilirubin concentration was found. Consistent blood sampling sites should be used for laboratory tests where arterial, venous, and capillary results differ or could conceivably differ.

Arteries↗
PubMed1984

Gram's stains of tracheal secretions predict neonatal bacteremia.

The presence of bacteria in tracheal secretions stained by the Gram method was evaluated as a method of predicting neonatal bacteremia. The presence of bacteria had a 74% sensitivity and a 47% predictive accuracy in identifying neonates with bacteremia before 12 hours of age. The specificity in predicting newborns without bacteremia was 98%. In the same neonates, an immature neutrophil-total neutrophil ratio of 0.2 or more had a 77% sensitivity in predicting neonates with bacteremia. Neonates with bacteria in their blood and tracheal aspirates, who died shortly after birth, had pneumonia on postmortem examination. In newborns who have respiratory distress and a risk of infection at birth, Gram's stains of tracheal secretions are a practical and useful method of predicting congenital bacteremia.

Bacteria↗