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Biomedical subjects

K H Charlton

Publications and source records attributed to K H Charlton.

7 recordsLinked to original sources
PubMed1981

Disparate diameter grafting. Astigmatism, intraocular pressure, and visual acuity.

We studied 180 consecutive corneal transplants performed by one surgeon to determine the benefit obtained by using a 0.5 mm oversize (OS) graft. We compared 61 same size (SS) grafts to 119 oversize (OS) grafts, with a mean follow-up time of 24 and 13 months respectively. While the refractive error, recovery of visual acuity, and intraocular pressure were similar in both groups, the astigmatism was found to be significantly elevated in the (OS) group. Using a 0.5 mm oversize graft did not afford any protection against postkeratoplasty glaucoma, did not increase the speed of recovery of the patients' visual acuity, but produced significantly more astigmatism than a same size graft.

Adult↗
PubMed1981

Pseudodendritic keratitis and systemic tyrosinemia.

Three children (6 eyes) with systemic tyrosinemia who presented with a diagnosis of herpes simplex keratitis are described. Two of the patients underwent extensive treatment for herpes simplex keratitis until their defects in tyrosine metabolism were discovered. All three children responded favorably to a low-tyrosine diet. These cases illustrate the typical corneal findings of the Richner-Hanhart syndrome (pseudodendritic keratitis, hyperkeratotic skin lesions of the palms and sole without mental retardation). The findings in these three patients were similar to those cases previously reported in the literature except none had mental retardation. The ophthalmologist confronted with a young child with bilateral dendritiform keratitis should request evaluation of the serum tyrosine levels.

Amino Acid Metabolism, Inborn Errors↗
PubMed1981

Visual prognosis in pseudophakic corneal transplants.

Although the prognosis for obtaining a clear corneal transplant after aphakic bullous keratopathy is good, many patients do not achieve good vision primarily because of macular disease. To evaluate the visual benefit of an intraocular lens on corneal transplantation, we performed a retrospective study comparing the best attained and latest visual acuities, corneal thinning patterns, endothelial cell densities, and postkeratoplasty complications in 31 patients with aphakic bullous keratopathy, 19 patients with pseuodphakic bullous keratopathy, 44 combined transplants with cataract extraction and 5 secondary lens implants at the time of keratoplasty. We found the presence of a lens provided patients with early functional visual rehabilitation. Subsequent visual acuity was equivalent in similar corneal disease categories. The presence of a lens did not produce additional endothelial cell loss, abnormal corneal thinning patterns, or increase the incidence of complications. The removal of an intraocular lens at transplant did not affect ultimate visual prognosis. We conclude that the implantation of an intraocular lens does not increase complications after keratoplasty in selected cases.

Aged↗
PubMedDate not supplied

Surgical procedures performed after refractive surgery.

BACKGROUND: Refractive surgical procedures have been performed for over one decade. The complications that cause visual disability are abnormalities in wound healing, residual ametropia, and/or severe irregular astigmatism. Many of these complications can be manifested clinically in terms of visually disabling problems (loss of best-corrected vision, glare, monocular diplopia, etc). Some of these complications require additional standard ophthalmic or refractive surgical procedures to restore vision. However, since these secondary procedures have been performed in only a few cases, we known little about their outcome. METHODS: We report the histopathologic analysis of 132 cases that have undergone a secondary surgical procedure following a primary keratorefractive procedure. We attempt to correlate the problems encountered with such secondary intervention with histopathologic information obtained from specimens that have been submitted to our pathology laboratory and that had undergone secondary surgical procedures. RESULTS: Many specimens displayed abnormalities in wound healing associated with visual difficulties such as loss of best corrected acuity, glare, and under- and overcorrection. A short time from the initial procedure to the time of secondary intervention was common. CONCLUSIONS: The combination of a secondary surgical or keratorefractive procedure can produce unpredictable refractive results. Judicious application of a refractive procedure and an appropriate time period before a second procedure is performed may reduce unexpected refractive complications.

Adult↗