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Biomedical subjects

K H Grözinger

Publications and source records attributed to K H Grözinger.

At least 19 recordsLinked to original sources
PubMed1980

[Cholesterol in the blood and bile].

In a prospective study serum and bile cholesterol concentrations were examined in 233 patients with gallstones. The objective of the study was the selection of patients in which conservative dissolution of gallstones might be successful. The average concentration of cholesterol in serum was 227,46 +/- 41,64 mg/100 ml, in gallbladder bile 8,83 +/- 5,66 mg/100 ml. The cholesterol contents of gallstones was 73,47 +/- 19,47 per cent. Statistical relations were found neither between the cholesterol concentrations in serum and bile nor between the cholesterol contents of gallstones and the cholesterol concentrations in serum and bile. The postoperative cholesterol concentration in serum was remarkably diminished as compared with preoperative values in all patients. A statistically significant decrease of serum cholesterol was seen in patients with histologically proven fatty liver disease. Measuring the cholesterol concentration in serum is no appropriate way for the selection of patients with gallstones for a litholytic treatment. It should be evaluated whether a concomitant fatty liver disease is an indication for a therapeutic trial with chenodesoxycholic acid.

Adult↗
PubMed1980

[Microbiological and histologic correlations in inflammatory gallbladder disease (author's transl)].

In a hospital population of 243 patients undergoing surgery for gallstones, inflammatory alterations were seen in 177 cases. The search for bacteria was positive in 33 cases. Thus, more than 80 per cent of the cholecystitis cases were abacterial. Under the age of 50, micro-organisms were found in 4.5 per cent only, and in 37 per cent of patients above fifty. In 11 cases of acute cholecystits no bacteria were found at all. Antibiotic treatment is justified in high-risk patients.

Adult↗