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Biomedical subjects

K H Jacobasch

Publications and source records attributed to K H Jacobasch.

6 recordsLinked to original sources
PubMed1990

[Autoradiography of DNA synthesis in colonic mucosa of patients with familial adenomatosis coli].

In connection with routine endoscopic examinations of 31 patients with familial adenomatosis coli and 28 health kindreds of patients with familial adenomatosis coli we investigated by autoradiography the in vitro incorporation of 3H-thymidine into bioptic mucosal particles from colon and adenomas. Within the 5-year follow-up period there was found a significantly increased labelling index of polyps and the surrounding mucosa in patients with polyposis independing on the time elapsed after operation. In 12 of 28 kindreds the histological normal colonic mucosa showed an increased labelling index too. The prognostic value of these results must be proofed by further controls.

Adenoma↗
PubMed1989

[Cell proliferation of the intestinal mucosa in patients with familial adenomatosis coli. Autoradiography study].

In connection with routine endoscopic examinations of 31 patients with familial adenomatosis coli and 28 healthy kindreds of patients with familial adenomatosis coli we investigated by autoradiography the in vitro incorporation of 3H-thymidine into bioptic mucosal particles from colon and adenomas. Within the 5-year follow-up period there was found a significantly increased labelling index of polyps and the surrounding mucosa in patients with polyposis independing on the time elapsed after operation. In 12 of 28 kindreds the histological normal colonic mucosa showed an increased labelling index too. The prognostic value of these results must be proved by further controls.

Adenomatous Polyposis Coli↗
PubMed1976

[Experiences with coloscopy].

The introduction of fully flexible coloscopes has considerably contributed to the improvement of the diagnostics of the large intestine. According to the hitherto got experiences is to be expected that this method will contribute to the possibility of diagnose malignant and benign colon processes earlier and more exactly. In the paper the methodology of the coloscopy is described and it is referred to its difficulties and complications. The indications and contraindications for the coloscopy are described. It is reported on first results after a one-year experience with coloscopy. The conclusion is that in patients with radiologically and rectoscopically not clarifiable, referring to a severe disease of the colon, symptoms a coloscopy should be carried out.

Adolescent↗