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Biomedical subjects

K H Jensen

Publications and source records attributed to K H Jensen.

At least 19 recordsLinked to original sources
PubMed1992

[Who has gallstones? Current epidemiologic studies].

Until a few years ago, our knowledge about the epidemiology of gall-stones was limited on account of the absence of diagnostic methods for investigation of extensive populations. Development of ultrasound scanning has had the result that, within the past six or seven years, a number of screening investigations for gall-stones in populations selected at random have been undertaken. These investigations reveal that the great majority of cases of gall-stones are undiagnosed. The prevalence increases with the age and is higher in women than in men. The latter observation is due to factors which are specific for women, mainly pregnancies but possibly also employment of hormones and the duration of the fertile period. Familial accumulation of gall-stone disease is also observed. Obesity, smoking and abstinence from alcohol appear also to be related to gall-stones while the significance of diet is still poorly elucidated. Gall-stones appear to be associated with both lipid and glucose metabolism. During the coming years, a series of incidence investigations may be anticipated and these will further increase our knowledge about risk factors for gall stones.

Adult↗
PubMed1991

[Spiral fracture of the humerus during arm wrestling].

The authors present the case of a body-builder who sustained a spiral fracture of the humerus during arm wrestling (Indian wrestling). The cause of the fracture and the underlying mechanism are discussed and it is concluded that it appears appropriate to warn body-builders and weight-lifters against arm wrestling.

Adult↗
PubMed1991

[Who has gallstones? Recent epidemiological studies].

Until a few years ago, our knowledge about the epidemiology of gall-stones was limited on account of the absence of diagnostic methods for investigation of extensive populations. Development of ultrasound scanning has had the result that, within the past six or seven years, a number of screening investigations for gall-stones in populations selected at random have been undertaken. These investigations reveal that the great majority of cases of gall-stones are undiagnosed. The prevalence increases with age and is higher in women than in men. The latter observation is due to factors which are specific for women, mainly pregnancies but possibly also employment of hormones and the duration of the fertile period. Familial accumulation of gall-stone disease is also observed. Obesity, smoking and abstinence from alcohol appear also to be related to gall-stones while the significance of diet is still poorly elucidated. Gall-stones appear to be associated with both lipid and glucose metabolism. During the coming years, a series of incidence investigations may be anticipated and these will further increase our knowledge about risk factors for gall-stones.

Cholelithiasis↗
PubMed1991

Incidence of gallstones in a Danish population.

Five-year incidence of gallstone disease was assessed by ultrasonography in an age- and sex-stratified random population of Danish origin aged 30, 40, 50, and 60 years. The response rate was 82.8% (2987/3608). Nonrespondents did not differ from respondents regarding variables concerning gallstone disease. The 5-year incidence of gallstone disease in men aged 30, 40, 50, and 60 years was 0.3%, 2.9%, 2.5%, and 3.3%. Corresponding figures in women were 1.4%, 3.6%, 3.1%, and 3.7%. The incidence of gallstones was significantly higher in subjects aged 45 years or more compared with those aged 35 years. The sex difference in gallstone incidence decreased with increasing age. A significantly higher incidence of gallstone disease was found among subjects with former polyps in the gallbladder. Spontaneous disappearance of gallstones was seen in 4.5%.

Adult↗
PubMed1990

[Gluteal compartment syndrome].

The gluteal compartment syndrome is a condition which has rarely been described. Most frequently, it is caused by violent injury. A case which was precipitated by intramuscular injection in connection with anticoagulation treatment and which involved the sciatic nerve is described.

Buttocks↗
PubMed1990

Polyps in the gallbladder. A prevalence study.

The prevalence of gallbladder polyps as assessed by ultrasonography in a random population was 4.6% among men and 4.3% among women. The size of most polyps was 3 mm or more but never exceeded 10 mm. The prevalence of polyps was not significantly associated with age, sex, social factors, weight factors, physical activity, diabetes mellitus, pregnancies, use of exogenous female hormones, intake of alcohol, or plasma lipids. Polyps among men were significantly associated with a history of no smoking. This lack of risk factor profile resembled that of cholesterolosis, as seen in the literature, whereas it was quite different from that of gallstones. It is concluded that polyps in the gallbladder are common in a random population, and, although it is known from the literature that some cases may represent gallstones, the vast majority most probably represent the polypoid variation of cholesterolosis.

Adult↗
PubMed1989

[Intermittent claudication--social aspects in young patients not undergoing surgical treatment].

A total of 107 patients suffering from intermittent claudication (CI) was studied after a mean observation time of 5.9 years. Thirty-one (29%) had died during the observation period. A questionnaire was sent to 76 patients and 78% replied. All patients were under 50 years of age at the first consultation. No patients had been operated upon. The ratio women:men was 1:1.3. 33% received disability pensions or some other kind of pensions. Fifty-eight had limited their spare-time activities because of CI. It is concluded that a close control and reconstructive arteria surgery must still be recommended when the working ability is threatened.

Adult↗
PubMed1988

Peritonitis caused by abscess in the seminal vesicle. Case report.

Acute seminal vesiculitis is rare. It is most often associated with prostatitis and epididymitis. A case is presented in which a ruptured abscess of the seminal vesicle caused diffuse peritonitis. There appears to be no previous report of such abscess, which thus seems to be a very rare cause of acute abdomen.

Abscess↗
PubMed1987

Mechanical strength in rat skin incisional wounds treated with fibrin sealant.

The biomechanical strength of skin incisional wounds of rats treated with fibrin sealant was assessed by in vitro determination of maximum tensile strength and relative failure energy. Wounds adapted without application of fibrin sealant served as control. Both types of wounds were fixed with surgical tape for the first 8 days of healing. Measurements were performed after 0, 2, 4, 8, 20, and 42 days of healing. After 2 days of healing, wounds treated with fibrin sealant possessed increased maximum tensile strength and relative failure energy. This increase corresponds to the initial strength of the fibrin sealed wounds (0 day values). After 4 and 8 days of healing, no differences were found between the sealed and unsealed groups. After 20 days, the pattern had changed showing increased tensile strength and relative failure energy in wounds not treated with fibrin sealant. A similar trend was reported after 42 days of healing. In both sealed and control wounds, an increase in strain at maximum stress during healing was most pronounced in the first 8 days. After 2 days of healing the strain at maximum stress was increased in wounds treated with fibrin sealant.

Animals↗
PubMed1986

Biogenesis of photosystem II complexes: transcriptional, translational, and posttranslational regulation.

The integral membrane proteins of photosystem II (PS II) reaction center complexes are encoded by chloroplast genomes. These proteins are absent from thylakoids of PS II mutants of algae and vascular plants as a result of either chloroplast or nuclear gene mutations. To resolve the molecular basis for the concurrent absence of the PS II polypeptides, protein synthesis rates and mRNA levels were measured in mutants of Chlamydomonas reinhardtii that lack PS II. The analyses show that one nuclear gene product regulates the levels of transcripts from the chloroplast gene encoding the 51-kD chlorophyll a-binding polypeptide (polypeptide 5) but is not involved in the synthesis of other chloroplast mRNAs. Another nuclear product is specifically required for translation of mRNA encoding the 32-34-kD polypeptide, D1. The absence of either D1 or polypeptide 5 does not eliminate the synthesis and thylakoid insertion of two other integral membrane proteins of PS II, the chlorophyll a-binding polypeptide of 46 kD (polypeptide 6) and the 30-kD "D1-like" protein, D2. However, these two unassembled subunits cannot be properly processed and/or are degraded in the mutants even though they reside in the membrane. In addition, pulse labeling of the nuclear mutants and a chloroplast mutant that does not synthesize D1 mRNA indicates that synthesis of polypeptide 5 and D1 is coordinated at the translational level. A model is presented to explain how absence of one of the two proteins could lead to translational arrest of the other.

Chlamydomonas↗