PubMed Health⌕ Search

Biomedical subjects

K H Müller

Publications and source records attributed to K H Müller.

At least 73 records · Page 4Linked to original sources

[The fixateur-externe-osteosynthesis without osseous support (external distance-osteosynthesis) in the lower limbs. Biomechanic, surgical and osteoplastic basic principles (author's transl)].

The stability of external distance osteosynthesis for complete tibia and femur defects rests solely on the rigidity of the external support. The rigidity of the external support is an function of the mechanical data of its individual elements, of the hold between the bone and the other system, as well as of the individually optimized construction form. The response of an osseous contact area which is not resistant to compression when external osteosynthesis is applied is mechanically similar to the response to distance osteosynthesis in the presence of a defect. The basic application rules for distance osteosynthesis of the lower limbs are given. The symmetric frame fixator applied in a three-dimensional arrangement is indicated for tibia defects. External distance osteosynthesis of femur defects can only be recommended when plate osteosynthesis alone or plate osteosynthesis in conjunction with a bracket fixator are out of the question. The various application forms for external osteosynthesis of femur defects are described and their indication with respect to knee function given. Although none of the construction forms for defects in the tibia and especially in the femur can eliminate mechanical interfragmental movement of the main fragments, their clinical use has been successfully established; however, surgical and osteoplastic measures must ensure more and more biological stability with time. The necessary surgical techniques and procedures are described. Whereas even extensive defects of the femur can be bridged exclusively with autologous cancellous bone, varied measures are required for the lower leg, depending on the various individual conditions. Should the direct bridging of the main tibia fragments not be appropriate, fibular-tibial synostosis is necessary. The various options for such fibular-tibial osteoplasty which may be required, depending on the individual case, are described.

Biomechanical Phenomena↗

A cooling chain for studies of cryofixed biological specimens by scanning transmission electron microscopy and X-ray microanalysis.

A cooling chain is described which enables the transfer of frozen hydrated biological specimens (ultrathin cryosections as well as about 1 micrometer thick cultured cells) from a cryoultramicrotome into a scanning transmission electron microscope with a field emission gun. Transfer is done at 118 K, specimen temperature in the microscope is 165 K. Sublimation processes are controlled visually and by mass spectrometry. Electron micrographs and X-ray microanalytical spectra of cryofixed unstained tissue culture cells and rat liver tissue sections are described and discussed. Contamination of the specimen is much reduced by use of the cold stage.

Animals↗

[Indications and complications in the treatment of infected femur pseudarthroses (author's transl)].

Indications given, the adequately dimensioned plate osteosynthesis must be preferred to any other treatment for stabilizing an infected femur pseudarthrosis, regardless of the osseous support. Otherwise the fixateur externe is indicated. Its assembly on the upper leg requires a special knowledge which reflects the individual bone- and soft-tissue-assessments. We distinguish between fixateur type I to IV on the upper leg, all of which are exemplified. Complications are at first mainly loss of blood and infective activity, later chronic soft-tissue fistulae, abscesses, osteomyelitic residual cavities, and spontaneous fractures. A study analyses the treatment and the late results of 96 infected femur pseudarthroses.

Adolescent↗

[The X-ray film of the petrosal bone in the special projection according to Chaussée III (author's transl)].

For the purpose of a better appreciation of the x-ray film of the petrosal bone in the special projection according to Chaussée III, the roentgenogram was divided into fifteen individual subsequent pictures and explained step by step. Together with the standard x-ray films, this particular roentgenogram provides a spatial idea of the tympanic cavity and enables accurate assessment of the destruction caused by chronic epitympanal otitis media as well as cholesteatoma. In many cases this eliminates the necessity of performing tomography of the middle ear.

Humans↗