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Biomedical subjects

K H Maurer

Publications and source records attributed to K H Maurer.

5 recordsLinked to original sources
PubMed1979

Hydroxyapatite phagocytosis by human polymorphonuclear leucocytes.

Hydroxyapatite crystals were incubated with human polymorphonuclear leucocytes and samples examined by light and electron microscopy after 3, 8, 30, and 120 minutes' incubation. Phagocytosis of crystals occurred at 3 minutes and increased with incubation. Degranulation of neutrophils, loss of cytoplasmic density, and cell necrosis were greatest in cells mixed with apatite and increased with time. Avid in vitro phagocytosis of hydroxyapatite crystals lends further support to the potential of these crystals as causes of human arthritis.

Humans↗
PubMed1976

Identification of drugs using a gas chromatography-mass spectrometry system equipped with electron impact-chemical ionization and electron impact-field ionizationfield desorption combination sources.

In a case of toxicological analysis by gas chromatography (GC)-mass spectrometry-data system, chemical ionization (CI), field ionization (FI) and electron impact data are shown to lead rapidly to assignments for all significant GC peaks. Valuable data include not only full spectra in the three ionization modes, but also exact mass measurements in the FI or CI mode. Such measurements, obtained by a dynamic peak-matching technique, lead to the elemental composition of the compounds of interest. This knowledge makes the assignment of key GC peaks unequivocal and provides an extremely high level of confidence regarding the identity of whole metabolite series. It is also shown that the nature of the FI information is very similar to that obtained from CI data.

Aminopyrine↗
PubMedDate not supplied

Further compounds from the pedal gland of the bontebok (Damaliscus dorcas dorcas).

The identification of four further major constituents of the pedal gland exudate of the bontebok, Damaliscus dorcas dorcas, viz. alpha-terpineol, 2-n-heptylpyridine, m-cresol and (A)-6-dodecen-4-olide and the investigation of the stereochemistry of the double bond in (Z)-6-dodecen-4-olide by means of iterative computer analysis are described. An improved synthesis of this compound is outlined.

Animals↗