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Biomedical subjects

K H Tonnesen

Publications and source records attributed to K H Tonnesen.

At least 19 recordsLinked to original sources

Subclinical ergotism.

The systolic blood-pressure at the ankle and the first toe was measured in 30 patients, mean age 42, who had taken ergotamine regularly for more than a year. With one exception, the patients had no symptoms or signs of arterial insufficiency in the limbs, but all had low-normal or abnormal foot systolic blood-pressures. In a group of 13 patients who stopped taking ergotamine the distal pressures rose significantly and from the ninth day were normal.

Adult↗

Compensatory renal hypertrophia in patients undergoing unilateral nephrectomy.

Estimations of the residual glomerular filtration rate (GFR) were made from renography and GFR measurements before unilateral nephrectomy in 28 patients aged 42-77 years. The GFR was measured one week and three months after the operation and comparisons were made between the function of the remaining kidney and the preoperative estimate. In 23 patients where the removed kidney had some function, the mean GFR increased by 32% and 22% after one week and three months, respectively. In 5 patients where the removed kidney had no function, no compensatory hypertrophy occurred.

Adaptation, Physiological↗

Residual kidney function after unilateral nephrectomy. Pre- and postoperative estimation by renography and clearance measurements.

The residual kidney function was predicted from preoperative renography and determination of the glomerular filtration rate (GFR) in 57 patients undergoing unilateral nephrectomy for cancer, postrenal obstruction or renovascular hypertension. Postoperative GFR measurements were carried out 6-36 months after the operation. In eleven patients where the kidney removed had no function, no significant difference was found between pre- and postoperative GFR values. In 46 patients where the kidney removed had some function, the preoperative estimate was a little too high in only two patients. In this group, the postoperative GFR on an average amounted to 42% above the preoperatively predicted value. We conclude that the combination of 51Cr-EDTA clearance and renography is a reliable, non-invasive method for determination of the minimum residual kidney function before unilateral nephrectomy is carried out.

Adult↗

Sudden massive hemorrhage after renal transplantation.

Five cases of sudden massive hemorrhage after renal transplantation are reported. It is supposed that an infective arteritis with damage of the artery wall caused the observed disruption of the arteries. Prompt ligation far from the infected site is recommended as necessary to prevent recurrence of the bleeding and to afford the best possibility for survival.

Adult↗