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Biomedical subjects

K Hänsgen

Publications and source records attributed to K Hänsgen.

At least 19 recordsLinked to original sources

[Doppler ultrasound evaluation of blood flow direction in distal occlusion of arteries of the lower leg].

It is necessary to observe the direction of the blood flow for measurement of the ankle pressure by the Dopplermethod. Obliteration of the ankle pressure by the Dopplermethod. Obliteration of the anterior tibial artery can be compensated by collaterals from the posterior tibial artery. Through this the blood flow is reversed in the dorsalis pedis artery. If this possibility is disregarded, the pressure of the anterior tibial artery will yield false data. The situation of the blood flow can be clarified by a compression test of the posterior tibial artery. This also applies to obliterations of the other arteries of the ankle.

Arterial Occlusive Diseases↗

[Arterial vascular diagnosis by Doppler pulse curve analysis of the first dorsal metatarsal artery].

In patients with peripheral arterial occlusive disease diagnostics by Doppler-sonography at the toe arteries and by Doppler-pressure measurement at the ankle arteries is often difficult and sometimes impossible. Using the first dorsal metatarsal artery for Doppler-waveform analysis yields exact information on haemodynamically relevant circulatory disturbances. Painful ulcers, gangrene, oedemata, mediasclerosis, burns, plaster casts, posttraumatic or postoperative conditions prevent the application of cuffs at the lower leg or foot. This Doppler-waveform analysis evidently represents the degree and the specialties of a disturbed blood circulation and allows an additional assessment of the vessels distal from the ankle arteries and enables a functional test on the anastomosis of the artery tibialis posterior and the artery dorsalis pedis. Functional and pharmacological influences on the tone of the vessels can be shown. The typical diagnostic features of Doppler-wave-form analysis used at the proximal measuring points are also valid at the dorsal metatarsal artery. The results of own comparative investigations in 69 patients and 44 healthy test persons are demonstrated.

Adult↗

[Incomplete thrombosis of the inferior vena cava, a cause of chronic recurrent lung embolism. Diagnostic possibilities and case report].

Detection of complete inferior vena cava thrombosis is relatively simple because of the clinical symptoms and the pathological results of cw Doppler sonography in the region of the common femoral vein. Drainage volume detectable by means of venous occlusion plethysmography is considerably reduced during the acute phase, but normalizes with increasing degree of collateralization. In case of incomplete inferior vena cava thrombosis clinical signs, cw. Doppler sonography and venous occlusion plethysmography are not very relevant. Therefore, imaging technique is additionally required. Basing on a case report, the article demonstrates that ultrasound-B-method and echocardiography, or preferable endoechocardiography, may contribute to a more reliable diagnosis. Cavography is still the gold standard if invasive therapy is planned.

Adult↗

[Incidence of hyperthyroidism in the Halle area before and after introduction of general preventive iodine treatment].

With an average frequency of more than 10% the former GDR is an endemic area of struma with an iodine insufficiency of second to third degree. After an effort for many years we succeeded in introducing the gradual prophylaxis with iodine preparations with the help of the action of an interdisciplinary iodine commission. After an initial addition of 25 mg of potassium iodide to the kilogram kitchen salt beginning with 1986 an iodination with 32 mg KJO3/kg was established for circa 85% of the so-called packet articles. At the same time an iodination of the mineral mixtures for the animal feed was performed. From the supplementation altogether resulted a daily iodine uptake of about 135 microgram. Apart from a reduction of strumata of newborn to lower than 1% further provable effects of the supplementation of iodine developed. Among others the losses of animals could be diminished and the production of meat and milk could be improved. In the animal production the annual losses in a value of more than 180 million GDR mark were eliminated. As the only side-effect foreseen an increase of the hyperthyroidisms by a factor between 2 and 3 appeared. It concerned both immunogenic and autonomy-caused overfunctions and is to be compared to the success of iodination known from other countries, egg. Tasmania. The cases of hyperthyroidism are transitory, in the course moderate and concern only already preformed, so-called latent form.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

[Venous capacity and drainage volumes of arm veins].

On 29 test persons after clinical angiological and cw-Doppler-sonographic exclusion of an obstruction of the deep veins and an arterial occlusive disease on the upper extremities the capacity of the veins and the drainage volume were determined by means of the venous-occlusion plethysmography. The angiological measuring places Compactus 540 and Periquant 3800, respectively, of the firm Gutmann (group 1) and the 2-channel occlusion plethysmography of the former nationally owned measuring device factory Ballenstedt (VEB Messgerätewerk Ballenstedt) (group 2) were at our disposal. Apart from the obsolute values of the capacity of the veins and of drainage volume on account of the large interindividual dispersions the quotients were determined in the comparison of sides. In the two groups the drainage volume showed significantly larger values on the right arm than on the left one. In group 2 the measuring of the capacity of the veins and the drainage volume resulted in essentially larger values than in group 1. In contrast to the absolute values the quotients of the measuring values did not show any significant differences between the two groups so that it seems that these are better suitable of the judgment of the venous obstruction behaviour.

Adult↗

[Blood fluidity in essential hypertension, arterial occlusive disease and diabetic angiopathies].

Microcirculatory disturbances are important complications in hypertension, arterial occlusive disease (PAVK) and diabetic angiopathies. The special haemorrheological diagnostics for the judgment of the terminal vascular bed tended to the comprehension of the haemorheological risk. Due to the increase of the aggregation of erythrocytes and viscosity of the plasma in peripheral arterial occlusive disease and diabetic angiopathies this risk proved to be distinctly increased, in diabetes mellitus without vascular complications and essential arterial hypertension it proved less distinctly increased. In hypertension the application of diuretic drugs should be done more critically and more controlled, in order to avoid conditions of hyperviscosity with their sequels for the microcirculation. The internal therapy in PAVK and diabetic angiopathies must include the amelioration of the disturbed blood fluidity.

Arterial Occlusive Diseases↗

[The effect of glycerol trinitrate on the arterial pressure of the fingers].

In 35 patients with healthy vessels, 52 patients with vasospasm and 42 patients with stenoses or obliteration of the finger arteries with the help of the Parks-ultrasound-Doppler device model 806-A and a finger cuff of the size of 3.5 X 5 cm the systolic pressure of the finger arteries was measured before and after the administration of glycerol trinitrate. Since in test persons with healthy vessels no significant differences of the radial and ulnar volar finger artery, of the single fingers of one hand or in the comparison of the sides of the two hands was found, a concentration could be done. The relative and absolute increase of the pressure of the finger artery under glycerol trinitrate was most conspicuous in patients with vasospasm. No essential changes, as we expected, occurred in patients with organic disturbances of the arterial blood supply. Under variation of the lower limits of the norm of the pressure of the finger arteries the high values of the sensitivity, specificity and efficiency which are characteristic for the ultrasound-Doppler pressure measurement, lying over 0.90 particularly after pharmacologic vasodilation.

Arterial Occlusive Diseases↗

[Diagnosis of angiologic function in unilateral leg edema following combined treatment of cervix cancer].

For the clarification of the genesis of a unilateral dropsy of the legs which had appeared in 16 women after operative and radiologic therapy of a carcinoma of the cervix apparative angiological functional investigations were carried out. A slightly diminished plethysmographic drainage volume in a Doppler-sonographically unhandicapped deep venous flow off corresponded to the clinical picture of the secondary lymphatic oedema. The findings were compared with the behaviour of the parameters in thrombosis of the iliofemoral vein and test persons with healthy vessels. Only in two cases a venous component in form of a stenosis of the pelvic veins and a postthrombotic syndrome, respectively, could be objectified. Since the methodology renders possible a differentiation of lymphatic oedema and phleboedema, it is suitable for non-invasive controls of the course and has practical significance in the after-care of female patients with carcinoma of the cervix.

Combined Modality Therapy↗

[Variability of the indices of vascular resistance in carotid Doppler sonography. Study of influencing factors in healthy vascular probands].

In 83 test persons with healthy vessels within the Doppler sonography the resistance indices of the internal carotid artery and the supratrochlear artery were established and in the various regressor combinations with the help of the multiple correlation influences of age, pulse rate, systolic blood pressure and diastolic blood pressure as well amplitude of blood pressure were tested. Thereby only the combination of systolic blood pressure and amplitude of blood pressure proved to be relevant. The confidence limits of the PWI of the right internal carotid artery and of the supratrochlear arteries of the two sides were established so that in findings with limit value it is easier to be stated whether the changes are only caused by circulation or they are reference to underlying stenoses. There were no significances as to the sides of the peripheral resistance indices.

Age Factors↗

[Doppler ultrasound parameters for peripheral arterial vascular diagnosis].

In order to control the valency of Doppler-sonographic parameters for the arterial vascular diagnostics, in patients with arterial obstructive disease apart from the measurement of the blood pressure characteristics of Doppler speed curves were analysed. Proximal obstacles of the vascular system of haemodynamic relevance led to the systolic decrease of pressure in the area of the extremities and to the monophasic configuration of curves with increased diastolic flow velocity and loss of the reflux component. Relations to the degree of severity of the ischaemia were found. The Doppler-sonographic comprehension of a changed local behavior of resistance and blood supply was valuable also for the differential diagnosis.

Arteriosclerosis↗

[Computer-assisted evaluation of bicycle ergometry].

The pedal ergometry is a reliable method for testing the functional capacity of patients with organic arterial obstructive diseases of the lower extremities. In order to lower the loss of time for evaluation pedal work and performance were calculated by means of a microcomputer KC 85/1 with the help of a basic programme using Hall switch circuits. The connection between working ability of the pedal, type of obstruction and pressure values of the posterior tibial artery is documented in the light of the measuring results of 61 patients with arterial obstructive disease of the lower extremities and of 32 test persons with healthy vessels.

Exercise Test↗

[Findings of pulse palpation and non-invasively measured blood pressure values of the posterior tibial artery in arterial occlusive disease].

In 37 test persons with healthy vessels and 103 patients with arterial obstructive disease the clinical findings of the pulse palpation were related to the results of the systolic Doppler pressure measurement in the region of the posterior tibial artery. The experience of the investigator, physical influences, local extravascular factors as well as parameters of the central haemodynamics proved to be significant. A palpation of the pulse was successful in peripheral systolic pressure values lying higher than 90 Torr, so that here a judgement of the function alone became possible with the help of the palpatory pressure measurement of the posterior tibial artery. Unfavourable local conditions, however, can be followed by negative tactile findings of the pulse also in higher pressure values.

Arterial Occlusive Diseases↗

[Results of hemodynamic functional studies in peripheral micro- and macroangiopathy].

In order to assess the functional haemodynamic effects of a peripheral micro- and macroangiopathy in 59 patients at rest and under ergometric load non-invasive measurements of blood pressure and blood flow were performed with the help of the Doppler sonography, the venous-occlusion plethysmography and the 133-xenon-clearance methodology. Type 1 diabetics with microangiopathy showed a restriction of the vasomotor reagibility and the width of regulation, they, however, did not show a decrease of the muscular working hyperaemia. The arteriosclerotic macroangiopathy led to a pathologic pressure and flow reaction on exertion. With the help of the Doppler sonography asymptomatic vascular changes could also be detected at the clinical stage I.

Adult↗

[Methodologic aspects and criteria for evaluating extracranial carotid Doppler sonography].

Doppler-sonographic and internal angiological findings of 57 patients with extracranial stenosis or obliteration of the internal carotid artery were evaluated. On the basis of the audio-signals and Doppler speed curves derived from the supratrochlear artery, the common and internal carotid arteries haemodynamically relevant extracranial obstructions of the vascular system could be objectified and judged with regard to their collateral compensation. Diagnostically valuable were the comparison of the sides and the additional calculation of the indices of the resistance. The Doppler sonography of the carotid artery should be used within the clarification of a cerebrovascular insufficiency and before every invasive diagnostics.

Aged↗

[Differential diagnosis of inflammation-induced arterial vascular diseases].

The clarification of non-arteriosclerotic inflammatory vascular diseases is based on angiological, angiographical, immunological and immunohistological methods and parameters. As causes of the arterial occlusive disease of younger patients are taken into consideration the obliterating endangiitis and Takayasu's aortoarteriitis. To the clinical manifestations of the giant cell arteriitis belong the temporal arteriitis and the rheumatic polymyalgia. Hypersensitivity and panangiitides are to be delimited from the group of the pathergic granulomatoses. The secondary Raynaud's syndrome on the basis of a digital arteriitis is of differential-diagnostic and prognostic importance in collagenoses and rheumatoid arthritis.

Arteritis↗