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K Hadano

Publications and source records attributed to K Hadano.

11 recordsLinked to original sources
PubMed1998

Effortful echolalia.

We report three cases of effortful echolalia in patients with cerebral infarction. The clinical picture of speech disturbance is associated with Type 1 Transcortical Motor Aphasia (TCMA, Goldstein, 1915). The patients always spoke nonfluently with loss of speech initiative, dysarthria, dysprosody, agrammatism, and increased effort and were unable to repeat sentences longer than those containing four or six words. In conversation, they first repeated a few words spoken to them, and then produced self initiated speech. The initial repetition as well as the subsequent self initiated speech, which were realized equally laboriously, can be regarded as mitigated echolalia (Pick, 1924). They were always aware of their own echolalia and tried to control it without effect. These cases demonstrate that neither the ability to repeat nor fluent speech are always necessary for echolalia. The possibility that a lesion in the left medial frontal lobe, including the supplementary motor area, plays an important role in effortful echolalia is discussed.

Aged↗
PubMed1997

Alcoholism and gene polymorphisms related to central dopaminergic transmission in the Japanese population.

We examined the association between gene polymorphisms related to central dopaminergic transmission and alcoholism in the Japanese population. Polymorphic gene loci examined included those encoding the dopamine D2 receptor (NcoI site and Ser-Cys site), the dopamine D3 receptor (BalI site), the dopamine D4 receptor (48 bp tandem repeat) and the dopamine transporter (40 bp tandem repeat). The genotype distribution at the NcoI site in the dopamine D2 receptor gene differed significantly (p < 0.5) between alcoholic patients and control subjects. The frequency of 7 repeats at the 40 bp/DAT tended to be higher (p < 0.1), and that of 9 repeats tended to be lower (p < 0.1) in alcoholic patients than in control subjects. The possible effects of dopamine-related gene polymorphisms, which might predispose individuals to alcoholism, are discussed.

Alcoholism↗
PubMed1986

[A case of jargon aphasia--a clinicopathological study].

An autopsied case of jargon aphasia by multiple cerebral infarction was reported. A 75-year-old right-handed woman developed a Wernicke's aphasia with the first attack of cerebral infarction in the left hemisphere in July 1980. With the second attack of infarction in October 1980, she developed a neologistic and semantic jargon aphasia, in which her speech consisted of neologisms, literal paraphasias, empty phrases and so-called "misused words". CT-findings showed two low density areas; one was in the left hemisphere and the other in the posterior region of the right hemisphere. Her jargon aphasia persisted for about one year. In November 1981, she suffered a third attack of infarction and developed an apallic syndrome. Neuropathological examination confirmed that the lesion of the right hemisphere played a decisive role in the outbreak of jargon aphasia in this case.

Aged↗
PubMed1984

On block design constructional disability in right and left hemisphere brain-damaged patients.

Block design tasks without or with special visual cues, tests of reasoning abilities and tests of spatial abilities were administered to 20 right and 20 left hemisphere damaged patients and 20 controls. Hécaen and Assal's (1970) hypothesis was not confirmed for block design constructional performance. Results of multiple linear regression analysis suggest that left hemisphere damaged patients adopt different strategies for the two different task situations.

Adult↗
PubMed1980

[Heterogeneity of bucco-facial apraxia].

The authors have studied the bucco-facial apraxia (BFA) in 20 aphasic patients, examining 10 isolated oral gesture (IOG) and 10 combined oral gesture (COG). The heterogeneity of the BFA is indicated by the qualitative analysis of the types of errors in COG in relation to IOG. It is probably that the BFA due to the posterior lesions might base on the motor programming disorders of oral gestures, and that the BFA due to the anterior lesions on the motor realization disorders of oral gestures. It remains unsolved whether there is a continuity or some varieties between two types of BFA.

Adult↗