[Triangular stress studies under hypoxia on mine rescue teams].
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Biomedical subjects
Publications and source records attributed to K Harzbecker.
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As a task in the research project Chronic Lung Diseases the method of testing bronchial reactivity by provocation with acetylcholine as an ultrasonic aerosol was developed. Indications for an uniform standardized application and policy are given.
Examinations performed with the help of the body-plethysmographic inhomogeneity parameter REmax/RE0 prove the close connection between the development of chronic unspecific pulmonary diseases and the appearance of disturbances of the ventilatory distribution. The functional disturbance metioned is further increased by the bronchial provocation and may partly be demonstrated in a characteristic way also in inconspicuous initial findings. The body-plethysmographic inhomogeneity parameter REmax/RE0 is, however, not suited for the early diagnosis of chronic unspecific pulmonary diseases, since with its help the verification of disturbances of the ventilatory distribution is successful only then, when the total resistance is already increased. For the final judgment of the aptitude of the bronchial reactivity test for the increase of the valency of methods of the distribution analysis in the early diagnosis further examinations are necessary.
In the last years the number of derivated electrocardiograms with several approaches to the problem has permanently increased. Therefore, the computer analysis seems to be obvious. The reliability of the analogo-digital-computer Express Analyzer Cardiograph EAC-2, Medexport Moscow, was for the employment for occupational medical examinations investigated on 252 experimental persons and compared with the independent manual analysis, which was carried out by two physicians. 80 per cent of the available ECGs were automatically correctly arranged into groups and all the inconspicuous electrocardiograms were sorted out, since it occurs on no account that an electrocardiogram which was recognized as pathological by means of manual analyses, was analysed as falsely normal by the computer EAC-2. Consequently, EAC-2 at low technical interference susceptibility may be very useful for the ECG-diagnosis by means of the computer during the screening investigations.
Among several variants of devices the infra-red thermography has obtained a wide technical perfection allowing to measure the thermal energy emitted from the body surface without contact, quickly and dynamically, and to produce a picture for analysis. Since numerous functional and pathophysiological proceedings are connected with changes of temperature, the use of thermography for diagnosis of processes near the body surface may be recommended. Based on thermic observations in 63 patients and a control experiment in 15 persons, experiences with the thermography in the diagnosis of diseases, which are localized more profoundly in the thoracic cavity, were reported.
Investigations for dose-effect relationship of acetylcholine-ultrasonic-aerosols (apparatus "TUR" USI3, duration of inhalation three minutes, control of the ventilation parameters five minutes after termination of inhalation) led to the result that the delimination of the bronchial hyperreactivity is already possible by application of a 0.01% test-concentration. In this way the ultrasonic-aerosol-method also leads to results which are comparable with the nozzle-aerosol-method used in GDR (0.5% test-concentration, duration of inhalation one minute). As a limiting criteria for the evaluation of a bronchial hyperreactivity analogous to the decrease in the FEV1 of greater than or equal to 15% in comparison with the starting position for the bodyplethysmography yield an increase of the resistance totalis of greater than or equal to 3.0 cm H2O/1/s.
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The microcatheterization for purpose of sounding of the right heart has proved itself in the prediagnostics of vitia cordis, for verification of the latent cor pulmonale, especially in combination with the bicycle ergometer load, and in the intensive medicine in the permanent measurement of the pressure of the pulmonary artery. The method gives the advantage of the frequent reproducibility and at the same time uncomplicated usability. In 3,342 microcatheter investigations only eight complications appeared (0.24% of the cases). Practical methodical references are given and possibilities of error in registering the pressure are indicated.
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