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Biomedical subjects

K Hasuo

Publications and source records attributed to K Hasuo.

At least 109 records · Page 6Linked to original sources

Computed tomography and angiography in MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes); report of 3 cases.

Among mitochondrial encephalomyopathies, MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes, Pavlakis et al. 1983) is recognized as a distinct syndrome characterized by generalized convulsions and recurrent stroke-like episodes. The neuroradiological findings of three patients with MELAS are reported here. Retrospective review shows that MELAS should be included in the differential diagnosis of infarct-like lesions of the cerebrum.

Acidosis, Lactic↗

Isolated unilateral absence of left pulmonary artery with peribronchial arteriovenous malformation showing recurrent hemoptysis.

Unilateral absence of a pulmonary artery is an uncommon condition and usually complicated by a cardiac anomaly. Our case is a rare one who showed the absence of the left pulmonary artery with left aortic arch and without cardiac anomaly. He suffered from recurrent hemoptysis and pneumonia since he was 9 months old. Angiography revealed peribronchial arteriovenous malformation of the affected lung which was supplied from subclavicular arteries and bronchial arteries. Although he was treated by operative ligation and angiographic embolotherapy of the supplying systemic arteries, the repeated the attacks of massive hemoptysis and necessiated left pneumonectomy at 10 years of age.

Arteriovenous Malformations↗

Spontaneous disappearance of a middle fossa arachnoid cyst associated with subdural hematoma.

The case of a 7-year-old boy with a middle fossa arachnoid cyst that spontaneously disappeared is presented. Computed tomography (CT) scan revealed an arachnoid cyst in the right middle fossa with a thin subdural hematoma on the same side. As the subdural hematoma spontaneously resolved, the cyst became smaller and finally disappeared without surgical intervention after 18 months on the follow-up CT scans. Possible mechanisms of the spontaneous disappearance of an arachnoid cyst are discussed.

Arachnoid↗

Oligodendrogliomas of the lateral ventricle: computed tomography and angiography.

Computed tomographic (CT) and angiographic findings in four cases of oligodendroglioma of the lateral ventricle are reported. CT showed a midline nodular intraventricular mass containing punctate calcifications and cysts. The tumors were slightly to markedly enhanced after the infusion of contrast media. Angiography showed slightly increased vascularity in the mass, and displacement of subependymal veins near the tumor. Oligodendrogliomas of the lateral ventricle are rare but should be included in the differential diagnosis of intraventricular tumors near the foramen of Monro.

Adult↗

Late infantile Krabbe leukodystrophy: MRI and evoked potentials in a Japanese girl.

A Japanese girl showed deterioration in development from the age of 13 months. At the age of 16 months, there were mild spastic diplegia, increase in cerebrospinal fluid protein to 61.5 mg/dl and deficient galactosylceramidase I. Magnetic resonance imaging (MRI) demonstrated a high signal intensity with increased T2 in the centrum semiovale. Short latency somatosensory evoked potentials (SSEPs) showed a prolonged N13-N20 interpeak latency followed by abolition of N20. Brainstem auditory evoked potentials (BAEPs) were normally followed by prolonged interpeak latencies of wave I-V. This may be the first report of what we consider to be the late infantile form of Krabbe disease with MRI and evoked potential examinations.

Brain↗

[Fusiform aneurysm of the vertebral artery presenting with foramen magnum syndrome: a case report].

A 33-year-old male developed stiffness of the left neck and pain of the left shoulder two years previously. Six months prior to admission, he noticed tingling sensation of the left 2nd, 3rd and 4th fingers and motor weakness of the left hand, both of which gradually progressed. On admission, positive neurological findings were neck pain on dorsal extension, left hemiparesis more advanced in the upper limb, diffuse muscle atrophy of the left upper limb, hyperreflexia of the left upper and lower limbs with positive Babinski sign and dysesthesia corresponding to the left C3-T5 sensory dermatomes. Enhanced CT and Metrizamide CT myelography showed a large extra- and intra-dural mass from the C1 segment to the medulla oblongata on the left. Angiography disclosed a fusiform aneurysm of the left vertebral artery. Proximal ligation of the left vertebral artery was performed. Postoperatively, clinical signs were markedly improved and shrinkage of the aneurysm was demonstrated on postoperative Metrizamide CT myelogram. Pathogenesis of diffuse muscle atrophy of the left upper limb was undetermined, but was probably not due to disturbance of the anterior spinal artery because of good visualization of the artery on the angiogram. Indication of the proximal ligation of the vertebral artery with an aneurysm was discussed.

Adult↗

Radiological analysis of hemifacial spasm with special reference to angiographic manifestations.

Fifty-one patients with hemifacial spasm secondary to facial nerve compression by normal appearing, elongated, tortuous and/or dilated arteries, were treated by microsurgical neurovascular decompression. Post-operatively, 91% of 44 of these patients with one to six year postoperative follow-ups were satisfactory. The angiographic findings showed significant increase in the number of common trunk anomalies. Variations of the anterior and posterior inferior cerebellar and vertebral arteries are discussed in relation to nerve compression.

Adult↗

Hemangiomas of the central nervous system in Japan: an epidemiological and clinicopathological study with special reference to venous and cavernous malformations.

Our experiences with cerebrovascular malformations in Japanese patients have been reviewed, presenting 29 cases of venous malformation, 30 cases of cavernous angiomas and one case of capillary telangiectasis. We also present the data from the 763 cases of AVM obtained in the cooperative studies which were supported by the Ministry of Health and Welfare of Japan, and discussed the epidemiological and clinicopathological aspects in relation to those reported in the literature. The cooperative studies on these subjects were primarily done in conjunction with the investigation of Moya-Moya disease which is by far frequently found in Japan. Regarding the vascular malformations of the C.N.S., there seem to be no noticeable differences in the epidemiological aspects as seen in Japan and in other countries. It should be stressed also from our experiences that all kinds of vascular malformation, either intracranial or intraspinal, bleed probably more often than we expect. Neurosurgeons should pay more careful attention to these vascular malformations with appropriate concepts of the disease.

Adolescent↗

Dumbbell-shaped spinal epidural cavernous angioma.

A case of a spinal epidural cavernous angioma extending in the intra- and extravertebral spaces through the intervertebral foramen is presented. It was dumbbell shaped, but did not show enlargement of the intervertebral foramen, a common sign that is thought to be helpful in the diagnosis of spinal neurinoma.

Epidural Space↗

Cerebral venous angioma of the pons: report of a case with pontine hemorrhage.

Cerebral venous angioma in the pons associated with pontine hemorrhage in a 39-year-old normotensive woman was identified with computed tomography and angiography. Venous angioma in the brain stem is usually silent and rarely found by chance at autopsy. Only a few cases have been clinically reported. Our report indicates that in unusual cases of intracerebral hemorrhage, vascular malformations should be suspected and scrutinized with radiologic examination including angiography.

Adult↗

[An autopsy case of malignant schwannoma in the brachial plexus extending into the spinal canal].

A 40-year-old woman had pain and numbness in the left upper extremity, on Dec. 1982. These symptoms progressed gradually. She was admitted to our department on Jan. 26, 1984 because of neck pains and progressive paraplegia. Neurological examination revealed monoplegia of the left arm with absent DTRs, spastic paraplegia, sensory disturbances below Th 11 level and severe sphincter disturbance. A metrizamide myelogram showed intradural extramedullary mass at C 4-7. Laminectomy was immediately performed from C 3 to C 7. A soft and brown tumor was attached at the ventral aspect of the cord at C 3 and C 7 and it was firmly attached at the root sleeve of the C 5 level. The histological diagnosis of the tumor was malignant schwannoma. One month later, she was discharged on foot. However, she was re-admitted to our department because of intractable pains in left neck and arm in Aug. '84. The second operation was done on Sept. 15. A soft and brown mass was found intra- and extradurally and it invaded into paravertebral muscules. On Sep. 30 '84 she died from respiratory failure. Postmortem examination revealed that intra-extradural tumor was found at C 4-Th 3, and the left brachial plexus was swollen. In the brachial plexus, the nerve fiber was replaced with tumor in the perineurium. The tumor invaded to the vertebral body and the paravertebral muscles. There were numerous metastasis of the tumor in both lungs. The tumor was formed by variable and scanty cytoplasm with many mitotic figures.(ABSTRACT TRUNCATED AT 250 WORDS)

Brachial Plexus↗

Moyamoya disease with a developmental anomaly of the mesenchyme.

We treated a Japanese boy with moyamoya disease accompanied by synbrachydactylia, funnel chest, pes equinus and short stature. Angiograms showed the anomalous origin of the occipital artery in addition to the moyamoya vascular network at the base of the brain. A generalised mesenchymal anomaly was suggested in this case.

Abnormalities, Multiple↗

Cerebral arteriovenous malformations in children.

Differences in clinical features of arteriovenous malformations (AVM) in six children with ruptured AVM (RAM) and three with unruptured AVM (URAM) are herein reported. The age at onset ranged from the neonatal period to 8 yrs in cases of URAM and 10 to 12 yrs in those with RAM. The children with RAM had a sudden onset of intracranial hemorrhage, except for one with prodromal symptoms such as vertigo or headache. The clinical features of URAM were chronic mild symptoms such as a certain degree of delayed development, focal neurologic signs or increased intracranial pressure in addition to macrocephalus and cranial bruit. CT scan revealed an evenly enhanced AVM and dilatation of ventricles in cases of URAM. The RAMs were angiographically relatively small while the URAMs were large.

Cerebral Angiography↗

Moya moya disease: use of digital subtraction angiography in its diagnosis.

Fourteen patients suspected of having Moya Moya disease underwent intravenous digital subtraction angiography (DSA), and the findings from nine of these patients were reviewed and analyzed. Obstruction or stenosis of the supraclinoid portion of the internal carotid artery and the proximal portions of the anterior and middle cerebral arteries was observed in all cases. Arteriography, however, was better than intravenous DSA in demonstrating Moya Moya vessels, differentiating complete occlusion from severe stenosis, and demonstrating important transdural collaterals. The disadvantages of intravenous DSA included inferior spatial resolution, the need for large amounts of contrast media, and relatively high radiation doses. Since the summation of vessels cannot be avoided using DSA, arteriography is necessary for the precise evaluation of cerebral hemodynamics before bypass surgery. Intravenous DSA is a safe, reliable method for diagnosing Moya Moya disease and is suitable for the screening and follow-up examinations of patients with the disease.

Adolescent↗