Biomedical subjects
Publications and source records attributed to K Hausegger.
A case of hypertrophic osteoarthropathy (HOA) caused by lung metastasis of an osteosarcoma in a 14-year-old boy and the remission of the HOA after intra-arterial chemotherapy is presented. The clinical, radiological and scintigraphic findings are discussed.
The results of computer-assisted static and dynamic renal scintigraphy in 57 patients with renovascular hypertension (RVH) and 23 patients with essential hypertension (EH) are presented. The following parameters were quantified: renal size (RS), count density (CD), relative unilateral renal clearance (RRC), mean parenchymal transit time (PTT), difference of time-to-peak of activity (tmaxd) to stenosed minus non-stenosed side, effect of frusemide (FE) and renal parenchymal radionuclide retention (RI). Among 57 stenosed renal arteries we detected 54 (true-positive cases) and missed three (false-negative cases); among 23 patients with EH and no significant haemodynamic renal artery stenosis, we found 21 cases correctly negative and two patients falsely positive. These data yielded a sensitivity of 95% and a specificity of 92%. The quantification of renal radionuclide studies in renal artery stenoses minimizes false-positive results and increases their specificity. This study shows that, because of its sensitivity, quantitative renal scintigraphy reliably allows the assessment of the functional haemodynamic effects of a renovascular lesion (significant stenosis) in the diagnostic work-up and during follow-up after surgical reconstruction or percutaneous transluminal angioplasty (PTA). The evaluation of renal function is in general greatly supported by the quantitative parameters, yet particularly after medication with converting enzyme inhibitors and after intervention.
High-resolution scrotal sonography proves valuable in addition to clinical investigation. On the basis of a retrospective analysis of 282 sonographic examinations this method's contributions to the differential diagnosis of diseases of the scrotum are shown. It is usually possible to distinguish testicular from extratesticular tumours; certain signs of inflammation allow the distinction between orchitis and tumour. Sonography is very important for the study of acute painful lesions of the scrotum, which are not palpable, such as rupture following a trauma, severe inflammation and even tumours.
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PURPOSE: Evaluate efficacy and safety of short-term thrombolysis with recombinant human-tissue plasminogen activator (rtPA). METHODS: Thrombolysis with rtPA was performed in 29 patients with angiographically documented severe acute pulmonary embolism (Miller score of 20/34 or more). All patients received 100 mg rtPA through peripheral veins within the first 2 hr, followed by a continuous infusion of rtPA (0.05 mg/kg/hr) over a 4-hr period. Concomitant intravenous heparin 1000 U/hr infusion was applicated for the first 6 hr. RESULTS: Using this treatment, 83% of our patients showed clinical improvement objectified by the Miller score, by the clinical stage (Grosser), and by the pulmonary artery mean pressure (PAPm). The treatment regimen was unsuccessful if the clinical history lasted more than 3 days. Complications occurred in 10 patients (34%), and 3 patients (10%) died of acute right heart failure. CONCLUSION: The success of rtPA treatment appears to depend on the interval between onset of symptoms and start of thrombolytic therapy. Otherwise the technique leads to objectifiable improvement within 6 hr with an acceptable bleeding risk.
The radiologic findings on plain chest films and contrast-enhanced computed tomography (CCT) of the thorax in a case of isolated persistence of the left superior vena cava associated with absence of the right azygos vein are described. Chest x-rays allowed a presumptive diagnosis of the vascular anomaly. Confirmation of this anomaly was achieved by CT.
Enteroenteric intussusceptions in adults are rare events caused by tumors in most cases. A case of duodenojejunal intussusception is presented which became manifest because of marked biliary obstruction and extensive pancreatic atrophy. As lead point, a large duodenal polypous hamartoma could be identified. The role of ultrasound and CT as diagnostic imaging of choice in this entity are discussed.
PURPOSE: To evaluate the effectiveness and cost of commercially available video conferencing units and standard Integrated Services Digital Network (ISDN) connections for real-time multi-site transmissions of interventional procedures. METHODS: A network of five separate interventional radiology departments-three in the Czech Republic and one each in Austria and the USA-was established using Polyspan (Polycom in the USA) View Stations and ISDN connections. This network was used for transmissions of 16 live interventional procedures to the Sixth International Workshop on Interventional Radiology in Prague, Czech Republic in June 2000. RESULTS: The transmissions were successful and of sufficient quality to contribute to the educational success of the workshop. The cost of the ISDN transmissions was a fraction of satellite transmission costs. CONCLUSION: Multi-site real-time interventional procedure transmissions using video conferencing Polyspan (Polycom) View Stations and ISDN connections are a promising means of improving interventional tele-education and decreasing its cost.