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Biomedical subjects

K Heide

Publications and source records attributed to K Heide.

At least 19 recordsLinked to original sources

[Assessment of AIDS risks: effects of different scale ranges and preventive knowledge].

In a sample of 552 respondents effects of different scale ranges and respondents' knowledge about AIDS for answering questions about AIDS-risks were examined. Knowledge was assessed with 12 items related to risks for HIV infections and preventive measures. AIDS hazards for different groups (prostitutes, fixers, hospital personnel, homosexuals, and haemophiliacs) had to be rated with five items, one for each group. Response variations were assessed in three parallel questionnaire versions with different ranges of risk assignments. Estimations had to be performed in comparison with the average population. Some groups were consistently rated to be at high risk, others were assigned low risks for becoming infected with the HIV-virus. The analysis of response patterns revealed that the three versions of numeric quantifiers determined the risk ratings only to some extent. The distribution patterns suggest that our subjects had an ordinal risk ordering in mind that might better be expressed in verbal terms. The knowledge about AIDS had no systematic effects on response behavior.

Acquired Immunodeficiency Syndrome↗

Treatment of akathisia with lorazepam. An open clinical trial.

Sixteen patients with neuroleptic-induced akathisia were treated with lorazepam. A marked improvement in symptoms was observed in 9 of the patient and moderate improvement in 5. Symptoms remained unchanged in 2 patients. The drop in the akathisia score from a pretreatment value of 1.81 to 0.5 after 7 days and to 0.32 after 14 days was statistically significant. Symptoms did not improve significantly during observation of the spontaneous course. No severe side effects were observed. The physiologic mechanisms of action of lorazepam on the akathisia syndrome are discussed.

Adult↗

[Elimination of rhesus (D)-incompatible erythrocytes by (Fab')2 G-anti-D (author's transl)].

The effectiveness of (Fab')2 G-Anti-D regarding elimination of D-incompatible fetal erythrocytes, and suppression of the formation of specific antibody, was investigated in 16 probands. Using 51Cr labelled D-incompatible fetal erythrocytes and simultaneous HbF-cell counting, fast elimination of incompatible red cells, and selective accumulation in the spleen, were observed after injection of small doses of (Fab')2 G-Anti-D. None of the probands showed active formation of anti-D after 3-12 months. The doses of the (Fab')2 G-Anti-D preparation used were similar to those employed in routine use of IgG-Anti-D. The results emphasize the importance of fast immunelimination of potentially antigenic red cells and thus point to a peripheral mechanism of anti-D prophylaxis by specific anti-D.

ABO Blood-Group System↗