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Biomedical subjects

K Hille

Publications and source records attributed to K Hille.

25 records · Page 2Linked to original sources
PubMed1998

[Eye and general illnesses in the public school for blind and visually handicapped students in Saarland. Developments in the last 20 years].

BACKGROUND: The aim of the study was the evaluation of how ophthalmological diagnoses and the proportion of multiply handicapped children has changed within the last 20 years at a state school for visually handicapped and blind children. PATIENTS AND METHODS: A profile investigation was conducted on all 105 children at the Landesschule für Blinde und Sehbehinderte des Saarlandes and compared to the results of an examination from 1975. RESULTS: The predominant ophthalmological diagnoses were: optic atrophy (17.5%), ocular albinism (11.9%), scar-stage IV and V of retinopathy of prematurity (11.1%), as well as tapetoretinal dystrophies with related syndromes (8.7%) and myopia magna (7.9%). Blind: 10.3% (1975: 36.4%); visually handicapped: 47.1% (1975: 49.2%); multiply handicapped: 42.5% (1975: 14.4%). CONCLUSIONS: (1) The diseases that dominated in earlier years in schools for the visually handicapped have become rare (cataract, aphakia, buphthalmia, macular dystrophy--all less than 5%); (2) the proportion of completely blind pupils has become much smaller; (3) there is an increasing tendency to educate visually handicapped pupils in regular schools with integrative aids; (4) there is also an increasing proportion of multiply handicapped children (school and kindergarten: 42%, early patronage 74%).

Blindness↗
PubMed1996

[Prospective study of surgical therapy of pterygium: bare sclera technique vs. free conjunctiva-limbus transplant].

Many techniques of pterygium surgery with various rates of recurrence are described in the literature. We report on the outcome after pterygium excision with bare-sclera technique compared with free transplantation of limbal conjunctiva. We used the bare-sclera technique in 21 eyes and performed free transplantation of conjunctiva in 34 eyes. The duration of follow-up was 14 months. In patients operated with the bare-sclera technique there were significantly more recurrences (eight vs four, P < 0.025) and cases of development of pyogenic granuloma (four eyes vs no eyes, P < 0.01). In patients with primary surgery and free limbal transplant we found no case of recurrence, but the bare-sclera technique was associated with a recurrence rate of 35.5% (P < 0.01). We recommend free limbal conjunctival transplantation even in patients with primary surgery of a pterygium.

Aged↗
PubMed1996

[Perioperative follow-up of physiologic and cognitive functions after oral premedication with midazolam 3.75 mg in women for retrobulbar anesthesia].

Recent changes in the medical system have resulted in a significant increase in the number of surgical procedures performed as day surgery. Therefore, a safe and short postoperative recovery period has become increasingly important. In the present study we investigated perioperative cognitive and physiological functions after oral premedication with low-dose midazolam (3.75 mg). The study was carried out on at total of 55 women (age > 60 years, weight 50-90 kg) scheduled for elective cataract surgery under retrobulbar anaesthesia (RBA), who were randomly assigned to either group 1 (n = 35) receiving 3.75 mg midazolam p.o. or group 2 (n = 20) receiving placebo p.o. 30 min prior to RBA. We measured the following parameters: sedation (modified Glasgow Coma Scale); anxiety (visual analogue scale); numerical and verbal memory (digit span and reproduction of previously presented words); concentration (revision test of Stender/Marschner). To identify depression of ventilation, pulse oximetric oxygenation and end-tidal PCO2 (nasal) were monitored intraoperatively. In the midazolam group anxiety was significantly lower and patients were significantly more sedated than in group 2. At a check 30 min after premedication with midazolam the scores for concentration and numerical memory were significantly (P < 0.05) lower. No differences between the groups could be found 2 h after the operations (2.92 +/- 35 min after premedication). Intraoperatively there was no significant difference in end-tital PCO2 and oxygenation between the groups. Oral administration of low-dose midazolam (3.75 mg) seems to be an appropriate form of premedication for ambulatory surgical procedures in elderly patients.

Aged↗
PubMed1995

[Granulomatous process of the optic papilla as an initial sign of systemic sarcoidosis].

Sarcoidosis is a systemic granulomatosis disease of unknown cause that may involve many ocular structures in about one third of cases. The findings of a posterior uveitis include vitritis, retinal periphlebitis, chorioretinal infiltrates, serpiginouschoroiditis, optic nerve atrophy and edema or granulomatous infiltration of the papilla. The central nervous system is clinically affected in 5 to 15% of cases. Despite several dozen published case reports of sarcoidoses of the optic nerve, direct infiltration of this structure is considered rare. We describe herein the case of 25-year-old white man whose only symptom of systemic sarcoidosis was optic nerve granuloma.

Adult↗
PubMed1994

[Non-syphilitic interstitial keratitis and inner ear deafness in the initial phase of Wegener's granulomatosis].

BACKGROUND: The aim of the present report is to briefly discuss the possible underlying diseases in a syndrome of nonsyphilitic interstitial keratitis and vestibuloauditory symptoms. PATIENT: A 46-year-old patient presented with interstitial keratitis, vestibuloauditory hearing reduction and necrotising atrophy of the nasal septum. RESULTS: Clinical tests for lues, tuberculosis, sarcoidosis and autoimmune diseases were negative. CONCLUSION: For clinical aspects Cogan's syndrome in association with an initial phase of Wegener's granulomatosis are discussed as possible underlying diseases.

Adrenal Cortex Hormones↗
PubMedDate not supplied

Risk factors for anatomical success and visual outcome in patients undergoing silicone oil removal.

PURPOSE: To define risk factors for anatomical success and visual outcome in patients undergoing removal of silicone oil. METHODS: This retrospective study included patients who had silicone oil removed at this hospital between 1996 and 2000. All were followed for at least six months. Patients with recurrent retinal detachment after silicone oil removal were compared with patients without this complication. We also compared patients whose vision improved or stabilized with patients whose vision deteriorated. Risk factors for anatomical success and visual outcome were identified. RESULTS: We analysed 94 eyes of 92 patients with silicone oil removal. Nineteen eyes (20%) had recurrent retinal detachment, and in 30 eyes (32%), the vision deteriorated after removal of the oil. Initial vision less than ambulatory vision, initial pathology of giant retinal tears and recurrent retinal detachment, postoperative hypotony and postoperative epiretinal membrane occurred more frequently in eyes with than without recurrent retinal detachment. Pre- and postoperative hypotony, postoperative epiretinal membranes and postoperative recurrent retinal detachment were also more frequent in eyes with deteriorated vision. CONCLUSIONS: When treating giant retinal tears or recurrent retinal detachments with silicone oil tamponade, surgeons and their patients need to be aware of the higher possibility of unfavorable results, particularly when the initial vision is less than ambulatory vision. The presence of risk factors before and after silicone oil removal should remind surgeons of the higher risk profile of this particular surgery.

Adolescent↗