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Biomedical subjects

K Honein

Publications and source records attributed to K Honein.

8 recordsLinked to original sources

[Multiple amebic liver abscess].

We report a case of multiple hepatic amebic abcesses, in a young Lebanese male patient living in Abidjan. These abcesses were revealed by fever and an acute pain in the right upper quadrant of the abdomen. Biological, namely serological, and ultrasonographic and magnetic resonance imaging abnormalities were noted. The patient responded favorably to metronidazole, and the short term evolution was good. A literature review was done, since the hepatic amebic abcess is becoming rare in our country.

Abdomen, Acute↗

[Detection of Helicobacter pylori by the urease test in 244 patients].

The authors report the results of the detection of Helicobacter Pylori (HP) in gastric mucosa by the urease test, in 244 patients between January 1989 and August 1991. The overall prevalence of HP was 38.1%. It was 19.5% in patients with normal upper gastrointestinal endoscopy (UE), 61% in duodenal ulcer (p < 0.001) and 68.7% in congestive antritis (p < 0.001), significantly higher than in controls. There was no significant difference between controls and patients with erosive antritis or healed duodenal ulcers. The prevalence of HP rises with age in all patients and in those with lesions at UE but not in those with normal UE. A rise of this prevalence seems to exist in the months of June and December. The authors conclude by pointing out the rise of the overall prevalence of HP in congestive antritis compared with erosive antritis, the similarity of prevalence in normal subjects and those with healed ulcer and the lack of influence of age on this prevalence in subjects with normal UE. These conclusions are in need of confirmation by further studies on much more longer series.

Adolescent↗

[Complications of endoscopic sclerotherapy of esophageal varices].

During the last decade, the endoscopic sclerotherapy has taken a prominent part in the treatment of digestive haemorrhage following up oesophageal varices rupture. Several complications have been reported after this method: Some of them are of no importance and frequent, occurring in 20 to 60% of cases, and essentially represented by retrosternal pains, dysphagia and fever. Others are major, observed in 16% of cases, with stenosis type or oesophagus perforation or pleuropulmonary lesions. Preventive measures, if well applied, could reduce the incidence of these complications observed after endoscopic sclerosis of oesophageal varices.

Endoscopy, Gastrointestinal↗

[Prevention of hemorrhagic recurrence in cirrhotic patients. Is sclerotherapy better than propranolol?].

The effectiveness of oral propranolol and sclerotherapy in preventing recurrent bleeding after an endoscopically proven haemorrhage from oesophageal varices was compared in Pugh's grade B and C patients divided into two successive therapeutic groups. Group I patients (n = 32) were given oral propranolol, while sclerotherapy was performed in group II patients (n = 32), 23 of whom simultaneously received propranolol. There was no difference between groups I and II in the severity of the initial bleeding and liver failure (Groups I/II, B 19/18, C 13/14), in the withdrawal of alcohol (group I 25, group II 17) and in compliance with either treatment (group I 25, group II 27). Obliteration of the oesophageal varices was achieved in 69 p. 100 of group II patients within a median number of 4 courses and 46 days, and in 84 p. 100 of the patients of this group who survived for more than 3 months. One year after the beginning of treatment rebleeding had occurred in 43 p. 100 of either group I or group II patients. The 1-year survival rate was 72 p. 100 in group I and 62 p. 100 in group II (non significant). The causes of death were the same in both groups. Irrespective of the treatment assigned, death was 2.1 times more frequent (P = 0.02) and rebleeding was 1.2 time more frequent (P = 0.08) in grade C than in grade B patients.

Esophageal and Gastric Varices↗

[Hemostatic embolization of hepatocellular carcinoma complicated by hemoperitoneum. Apropos of 2 cases and review of the literature].

Rupture of hepatocellular carcinoma is a severe complication that occurs in about 10% of patients. It may occur as a terminal event in patients with advanced disease or it may be the first presentation in a healthy individual. Various treatment options have been proposed, which include conservative treatment, transarterial embolization and operative hemostasis or liver resection. We report intraperitoneal hemorrhage and hypovolemia in two patients with spontaneous rupture of an hepatocellular carcinoma treated successfully by transarterial hepatic embolization. On follow-up, these patients died 7 and 8 months after this treatment respectively.

Aged↗

[24-hour esophageal pH monitoring in adults. Apropos of a series of 116 patients].

Between June 1994 and June 1996, we performed a 24-hour oesophageal pH monitoring in 116 adult patients. A retrospective analysis of the data is hereby presented. The principal indications include a chronic cough, recurrent laryngitis and noncardiac chest pain. In 65.5% of our cases, a pathological gastroesophageal reflux was found during pH monitoring. The symptom-index (SI) concerning the digestive and ENT symptoms did correlate in 1/3 of the cases while it was significant in only 15% of the cases with pulmonary and cardiac symptoms. 24-hour pH monitoring remains the method of choice for the study of gastroesophageal reflux and analysis of the SI is indispensable to evaluate the correlation of symptoms with episodes of reflux.

Adolescent↗