PubMed Health⌕ Search

Biomedical subjects

K Hozawa

Publications and source records attributed to K Hozawa.

41 records · Page 3Linked to original sources
PubMed1985

Experimental model for the otitis media with effusion induced by Arthus' reaction.

The Arthus' reaction in the middle ear cavity was studied using histochemical technique. The deposition of immune complex on the basement membrane and the immune complex in the middle ear effusion were the initial features of these animal models. But, these immune complexes were clearly removed from the tympanic cavity during the early phase of reaction. Immune complexes were supposed to be just a initiation of otitis media with effusion. The tubal dysfunction and local immunity of middle ear mucosa caused by the Arthus' reaction seemed to be responsible for the chronicity and relapsing of otitis media with effusion respectively.

Animals↗
PubMedDate not supplied

Vestibular sympathetic nervous system in guinea pig.

The vestibular sympathetic fibers were examined in 20 guinea pigs by the immunohistochemical demonstration of tyrosine hydroxylase and dopamine B-hydroxylase. The vestibular sympathetics originated in the ipsilateral superior cervical ganglion and entered the internal auditory meatus along the labyrinthine artery. At the Schwann-glial border, some of the sympathetic fibers left the artery and went into the superior and inferior divisions of the vestibular nerve and formed a loose meshwork among the Scarpa's ganglion cells, while other fibers continued to follow the labyrinthine artery. Both groups of fibers entered the cristae ampullares and saccular and utricular maculas after several bifurcations in the cribrose areas and terminated either near the capillaries beneath the sensory epithelia or among the vestibular nerve fibers. These fibers traveled freely in the vestibular labyrinth without being restricted to following blood vessels or vestibular nerve fibers. Some sympathetic fibers made direct contact with the vestibular efferent fibers or the vestibular afferent fibers at the node of Ranvier. Sympathetic fibers were not observed in the sensory epithelia or semicircular canals, and were rarely found in the vicinity of the dark cells.

Adrenergic Fibers↗
PubMedDate not supplied

Cholinergic and noradrenergic nervous systems in the cynomolgus monkey cochlea.

The cholinergic and noradrenergic nervous systems in the cochleas of cynomolgus monkeys were examined by histochemical and immunohistochemical demonstration of acetylcholinesterase (AChE) and tyrosine hydroxylase (TH) and/or dopamine B-hydroxylase (DBH), respectively. AChE activity was demonstrated in the efferent fibers making synaptic contact with the perikarya and the cell processes of type II neurons. Type II neurons also demonstrated AChE activity on the cell surface and their neurites, suggesting that the AChE-positive fibers in the simian cochlear nerve trunk, previously believed to be of efferent origin, are the central processes of type II neurons. TH-like and DBH-like immunoreactivity of beaded unmyelinated fibers demonstrated similar distribution throughout the cochlear nerve trunk, Rosenthal's canal, and osseous spiral lamina. During their course, they came in contact with unmyelinated efferent fibers and neurites of type II neurons and abutted blood vessels. However, their distribution was not restricted to following blood vessels or cochlear nerve fibers. These observations indicate that the sympathetic nerve supply and olivocochlear efferent system in the cochleas of monkeys differ from those of smaller animals.

Acetylcholinesterase↗