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Biomedical subjects

K Humphrey

Publications and source records attributed to K Humphrey.

8 recordsLinked to original sources

Orientation tuning of shape from shading.

Four experiments were performed to assess the effect of different orientations and direction of lighting on the visual processing of shaded or bipartite disks. In the first two experiments, observers were presented with nine different shading orientations from 0 degree to 180 degrees. Targets were detected in a rapid and parallel fashion for shaded disks when the orientation of the shading gradient was not horizontal (90 degrees) or oriented at 67.5 degrees. Search asymmetries favoring the detection of "pock" targets over "ball" targets were found for all orientations. The search rates for bipartite disks were similar to the shaded disks at 0 degree, 22.5 degrees, and 90 degrees but not for intermediate orientations, and no search asymmetries were found. These differences suggest that shaded displays and bipartite displays are processed by different underlying mechanisms. The third experiment showed that the direction of the light source (left or right) had no influence on search asymmetries around the 90 degrees point. Shading gradient orientation affected magnitude estimates of depth in the fourth experiment. These experiments show that the visual system's "assumption" of overhead lighting is broadly tuned.

Adult↗

Investigation of a unique male and female sibship with Kallmann's syndrome and 46,XX gonadal dysgenesis with short stature.

A sibship is described where the brother and a sister both have Kallmann's syndrome (anosmia and deficiency of gonadotrophin releasing hormone) and the woman also has streak ovaries. Although there are several conditions that may occur with Kallmann's syndrome, there are no known reports of ovarian dysgenesis being associated with this disorder. Cytogenetic analysis showed no rearrangement or major deletions of the chromosomes. Linkage analysis using informative microsatellite markers predicts that a gene other than KAL1 (at Xp22.3) is implicated in the Kallmann's syndrome manifesting concurrently with ovarian dysgenesis found in this family.

Adult↗

Developmental aspects of cross-language speech perception.

Previous research has suggested that infants discriminate many speech sounds according to phonemic category regardless of language exposure, while adults of one language group may have difficulty discriminating nonnative linguistic contrasts. Our study attempted to address directly questions about infant perceptual ability and the possibility of its decline as a function of development in the absence of specific experience by comparing English-speaking adults, Hindi-speaking adults, and 7-month-old infants on their ability to discriminate 2 pairs of natural Hindi (non-English) speech contrasts. To do this, infants were tested in a "visually reinforced infant speech discrimination" paradigm, while a variant of this paradigm was used to test adults. Support was obtained for the above hypotheses. Infants were shown to be able to discriminate both Hindi sound pairs, and support for the idea of a decrease in speech perceptual abilities wih age and experience was clearly evident with the rarer of the 2 non-English contrasts. The results were then discussed with respect to the possible nature and purpose of these abilities.

Child Development↗

Density dependence of signal detection in radiographs.

We report results of the variation of signal detectability with radiographic film density for Lanex screens and four different x-ray films. We found that maximum signal detectability occurs near (but not precisely at) the maximum slope of the characteristic curve. We interpret our results using a model that includes film gamma quantum noise, film granularity, and an intrinsic observer contrast threshold.

Evaluation Studies as Topic↗