K I Doudin | PubMed Health

PubMed2001

3,3'-Selenobis(propionic acid).

In contrast to Se[CH(2)C(O)OH](2) versus S[CH(2)C(O)OH](2), the title compound, Se[CH(2)CH(2)C(O)OH](2) or C(6)H(10)O(4)Se, is structurally quite similar to its sulfur analogue. The molecule has twofold symmetry. The C-Se-C bond angle is 96.48 (8) degrees and the Se-C bond lengths are 1.9610 (14) A. The shortest Se.O intermolecular distance is 3.5410 (11) A. The O.O distances in the carboxylic acid dimers are 2.684 (2) A. The temperature dependence of the IR spectrum suggests tautomerism in the solid state.

Journal Article↗

PubMed1989

Congenital chloride diarrhoea in Kuwaiti children.

Congenital chloride diarrhoea was diagnosed in 16 Kuwaiti children over a 7 year period (1980-1986) with an estimated incidence of 7.6 per 100,000 live births. The mean age at diagnosis was 3.2 months (range 1 week to 5 months). There were 9 boys and 7 girls with a mean age of 3 years 10 months (range 10 months to 7 years). All children had a shortened gestational period, abdominal distension and chronic diarrhoea. The serum electrolytes in all patients prior to treatment showed hyponatraemia, hypokalaemia, hypochloraemia and metabolic alkalosis. The diagnosis was confirmed by a stool chloride content that exceeded the sum of faecal sodium and potassium. Fifteen patients survived and showed catch-up growth with adequate replacement therapy and 1 died with renal failure.

Aldosterone↗