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Biomedical subjects

K I Qayed

Publications and source records attributed to K I Qayed.

7 recordsLinked to original sources

Could final year school grades suffice as a predictor for future performance?

The performance of three groups of medical students was evaluated at the end of one phase of their studies--after 2 years of premedicine. The aim of the study was to determine whether any of the assessment methods--secondary school grades, entrance examination or test for proficiency in the English language, used for selection of medical students, could reliably predict student performance in the early stages of their education. A significant correlation was found between secondary school grades and the entrance exam on the one hand and grade point average (GPA) on the other. However the results of the test for English proficiency did not correlate with the GPA. It is concluded that the secondary school grade on its own is a good predictor of academic performance in the early stages of medical undergraduate education.

Education, Medical, Undergraduate

The pyloric atresia-junctional epidermolysis bullosa syndrome. Report of a case and review of the literature.

BACKGROUND AND METHODS: The concomitant occurrence of the two rare conditions of pyloric atresia (PA) and inherited epidermolysis bullosa (EB) is not as rare as would be expected. We collected 41 case reports in the world literature and add a personal case in which EB was investigated with modern methods and found to be a GB3-positive/non-Herlitz junctional variant. OBSERVATIONS: Our review of the PA-EB association discloses that it is an autosomal recessive inherited entity in which EB is of the junctional EB (JEB) subtype and PA is a primary manifestation rather than a scarring process secondary to JEB. The disease is thus better called "PA-JEB." Patients with the PA-JEB syndrome present, not uncommonly, with erosions and/or subepithelial cleavage in the respiratory, gastrointestinal, and urinary tracts. In addition, certain facultative features are unique to PA-JEB, ie, obstruction of the ureterovesical junction and high incidence of a peculiar form of aplasia cutis congenita. CONCLUSION: The GB3 monoclonal antibody was found normally expressed in three of three cases, excluding the Gravis-Herlitz variant, in spite of an unmatching EB phenotype in one case. Further studies are needed to assess which of the JEB varieties are present in the PA-JEB syndrome.

Epidermolysis Bullosa, Junctional

Mal de Meleda: recessive transgressive palmoplantar keratoderma with three unusual facultative features.

Mal de Meleda (keratoderma palmoplantaris transgrediens) is a rare autosomal recessive form of palmoplantar keratoderma characterized by hyperkeratosis of the palms and soles which appears soon after birth and progressively (progrediens) involves other areas (transgrediens) of the body skin. We report the case of a patient with mal de Meleda with three unusual facultative features, i.e. prominent knuckle pads, peculiar finger-nail anomalies and pseudo-ainhum on both fifth fingers. Four other members of the family are also affected by mal de Meleda.

Adult

A study of the attitudes of the foundation staff of a new medical faculty to problem-based learning.

The characteristics of the foundation staff of the United Arab Emirates (UAE) University Faculty of Medicine numbering 18 were studied using open-ended questions in an interview setting. All were experienced academically with mean total years of experience being more than 20 years. The mean age of 51.7 years indicated that the majority of staff interviewed were in the latter stage of their academic career. Although one of the criteria for accepting candidates was flexibility in their outlook to new teaching learning systems and positive attitudes to problem-based learning (PBL), only seven understood PBL and five were openly hostile to the system. The reasons for joining the Faculty were protean, but most saw the job as being challenging in nature and a change from routine. The question is raised whether the selection procedure was appropriate and whether more stringent criteria might have been applied, to have included attitudinal aspects in addition to the academic achievements of the candidates, for the rightly motivated and oriented individual to be appointed.

Adult

Mal de Meleda: a report of four cases from the United Arab Emirates.

Mal de Meleda (MDM), or recessive transgressive palmoplantar keratoderma, is a rare disorder. MDM may have originated as a founder mutation that occurred on the island of Meleda, now Mljet, in Croatia, where it was first described. However, the condition has also been observed in countries distant from Mljet. The presentation of the disease in young patients has not been reported and the progressiveness of the lesions is debated. We examined four young United Arab Emirates nationals patients (ages 7 months to 12 years) who presented with keratoderma palmoplantaris (KPP) and transgressive pachyderma (TP) that had both been present before 1 year of age. KPP and TP were more pronounced in the two oldest patients. Family histories were consistent with autosomal recessive inheritance. The development of MDM lesions appears to be age-related. However, environment and individual factors may also play a role in the development and persistence of the lesions. Molecular genetic studies are necessary to establish whether the broad clinical presentation of the disease is due to allelic or genetic heterogeneities.

Child