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Biomedical subjects

K I Volkova

Publications and source records attributed to K I Volkova.

At least 19 recordsLinked to original sources
PubMed2003

[Stage I-III pulmonary sarcoidosis complicated by nephrogenic (vasopressin-resistant) form of diabetes insipidus].

Literature data and original experience of the authors with 6890 cases of respiratory sarcoidosis (stage I-III) suggest that diabetes ipsipidus in respiratory sarcoidosis (RS) can present as hypothalamic-hypophysial form (observed at the stage I-II by physicians since 1935) and a new form--nephrogenic (vasopressin-resistant) at stage II of pulmonary sarcoidosis. The latter form is little known. It was found that in stage III sarcoidosis patients who have severe fibrosis of the lungs and a long history of corticosteroid hormone treatment the nephrogenic form of the pathogenesis is caused by defects in calcium metabolism leading to nephrocalcinosis with low sensitivity of renal tubular receptors to ADH. Adiurecrine treatment is unefficient. It is recommended to use chlorpropamide which raises sensitivity of the tubules to ADH.

Diabetes Insipidus↗
PubMed2003

[Post-tuberculous fibrous mediastinitis: a report of a case followed-up for many years].

The paper reports a rare case of fibrosing mediastinitis of posttuberculous genesis caused by infection with Mycobacterium bovis. Such cases are not available in the literature so far. The patient was observed from 1956 to 2001. Bovine tubercle bacilla affect mediastinal lymph nodes which undergo fibrosis resulting in stenosis of the trachea, major bronchi, esophagus. Narrowing of the chest duct leads to formation of severe recurrent transudate in the left pleural cavity (for 3 years 70 pleural punctures were made with removal of a total of 22 l of fluid).

Fibrosis↗
PubMed1996

[Genetic markers of the ABO blood system in pulmonary sarcoidosis patients of different ethnic origin].

Analysis of published data and investigations of their own permitted the authors to detect the relationship between the incidence of AB0 blood groups and the ethnic appurtenance. The 0(1) and A(II) blood groups were appreciably more incident in the Europeans, including the Russians, whereas in the Asians (Kazakhs et al.) the B(III) group prevailed. In the Russian sarcoidosis patients groups A(II), less frequently B(III) predominated. The clinical course of sarcoidosis is more benign in patients with the 0(I) group, the initial and first stages of the disease predominating. In patients with the A(II) group sarcoidosis runs an unfavorable course, with the second and third stages predominating, and hence, patients with this blood group should be singled out as the risk group.

ABO Blood-Group System↗
PubMed1991

[Genetic blood markers of the ABO system in patients with pulmonary tuberculosis in relation to ethnic origin].

The literature data and the results of a study of genetic blood markers of the ABO system in pulmonary tuberculosis patients and in 1947 donors (control group) are given in relation to the ethnic appurtenance. There is a relation between the incidence of a blood group to the ethnic appurtenance and nationality of the subjects examined. For example, in Asian subjects (Kazakhs) the B(III) blood group is much more common, while the O(I) and A(III) blood groups are in the Europeans. The nature of the specific process depended, to a certain degree, on the blood group. The minor forms of tuberculosis and a more benign course were typical of 0(I) and A(II) groups, while in B(III) groups the process course was unfavourable with a tendency to destruction which is responsible for the formation of additional high risk groups of tuberculosis contamination.

ABO Blood-Group System↗
PubMed1990

[Tuberculomas of the brain].

Literature data and individual observations of 5 cases with a rare disease, like tuberculoma of the brain, are presented. From the clinical point of view, the disease in children, aged 4-9 years, proceeds like cerebral tumor. A surgical intervention has revealed a tuberculoma of the cerebellum in 4 and that of the truncus cerebri in 1 patient. The diagnosis of tuberculoma of the brain was confirmed histologically. Clinico-laboratory data and the impact of tuberculostatic therapy in the postoperative period were studied.

Cerebellar Diseases↗