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Biomedical subjects

K Inazumi

Publications and source records attributed to K Inazumi.

7 recordsLinked to original sources
PubMed2001

Ultrasound biomicroscopic diagnosis of cyclitic membranes.

PURPOSE: To evaluate the utility of ultrasound biomicroscopy in imaging cyclitic membranes. METHODS: Patients with hypotony and suspected or known cyclitic membrane underwent ultrasound biomicroscopic examination. Histopathology of cyclitic membrane was correlated with ultrasound biomicroscopy in three cases. RESULTS: Six eyes of six patients were enrolled. Mean patient age was 62.2 +/- 18.4 (SD) years. The mean intraocular pressure in the affected eye was 4.3 +/- 3.4 mmHg. Three eyes were pseudophakic and three eyes were aphakic. All eyes had undergone two or more previous intraocular surgeries. Ultrasound biomicroscopy imaged the cyclitic membrane in all six eyes. Histopathology revealed fibroproliferative cyclitic membranes with associated inflammatory cells. CONCLUSION: Ultrasound biomicroscopy is useful in detecting the presence of those cyclitic membranes that may not be identified on clinical examination.

Adult↗
PubMed1998

[Evaluation of the Swedish Interactive Thresholding Algorithm, a new thresholding algorithm, of the Humphrey field analyzer in normal subjects].

The Swedish Interactive Thresholding Algorithm (SITA) is a new thresholding algorithm that aims to obtain the same quality of visual fields in a shorter examination time than with the conventional up-and-down method. We investigated the correlation between thresholds measured with the SITA algorithm and those with the conventional up-and-down method in 47 eyes of 47 normal subjects. In each test point, thresholds with the SITA accurate and with the SITA fast showed significant correlation with those of the conventional method (r = 0.693, p < 0.0001 and r = 0.689, p < 0.0001, respectively). The mean deviation (MD) in the conventional method and the difference between MD values of the conventional method and SITA accurate and SITA fast were significantly correlated (r = -0.442, p < 0.006 and r = -0.509, p < 0.00092, respectively). The examination times of the SITA accurate and SITA fast were 48% and 27% of the conventional method. Although the new thresholding algorithm enables us to perform perimetric examination with relatively high accuracy, further investigations should be conducted before we apply it to glaucoma cases.

Algorithms↗
PubMed1998

[Evaluation of the Swedish interactive thresholding algorithm, a new thresholding algorithm, of the Humphrey Field Analyzer in glaucoma patients].

The Swedish interactive thresholding algorithm (SITA) is a new thresholding algorithm that aims to obtain the visual fields of the same quality in a shorter examination time than the conventional up-and-down method. We investigated the correlation between the threshold values obtained by SITA and the conventional thresholding algorithm in 30 glaucoma patients. The results of two types of SITA, i.e., SITA accurate and SITA fast, showed a significant correlation with those of the conventional method (r = 0.855, p < 0.0001 and r = 0.833, p < 0.0001, respectively). There was no statistical relation between the mean deviation (MD) of the conventional method and the difference between MD values of the conventional method, and SITA accurate and SITA fast. The examination time of SITA accurate and SITA fast was 50% and 31% shorter, respectively, than that of the conventional method. The difference in threshold of each test point in the conventional and SITA methods was minor except in one with a deep relative defect. These results indicate that SITA can be useful for detecting glaucomatous visual field defects in a shorter time.

Algorithms↗
PubMed1996

The effects of the beta-adrenergic-blocking agents, timolol and carteolol, on plasma lipids and lipoproteins in Japanese glaucoma patients.

PURPOSE: To determine whether two topical beta-blockers, timolol and carteolol, differently affect plasma lipids and lipoproteins in normolipidemic Japanese patients with glaucoma. PATIENTS AND METHODS: Thirty-three normolipidemic patients with primary open-angle glaucoma or ocular hypertension were randomly allocated to and completed 16 weeks of bilateral treatment with 0.5% timolol, 1.0% carteolol, or 2.0% carteolol twice daily in a three-center, prospective study. Patients using any drugs affecting plasma lipids or with a history of beta-blocker use of hyperlipoproteinemia were excluded. Fasting blood lipids and lipoproteins, including total cholesterol, high-density lipoprotein cholesterol, triglyceride, and apoproteins, were measured three times before therapy was initiated. These measurements were repeated every 4 weeks during the treatment period. RESULTS: The level of high-density lipoprotein cholesterol significantly decreased in the timolol treatment group but did not change in the carteolol treatment groups. The ratio of total cholesterol minus high-density lipoprotein cholesterol to high-density lipoprotein cholesterol increased in the timolol treatment group. CONCLUSIONS: Topical beta-blockers do affect plasma lipids in Japanese patients with glaucoma. The effects of timolol are greater than those of carteolol.

Adrenergic beta-Antagonists↗
PubMedDate not supplied

Inadvertent corneal indentation can cause artifactitious widening of the iridocorneal angle on ultrasound biomicroscopy.

A 70-year-old Asian female with narrow angles underwent ultrasound biomicroscopy (UBM) darkroom provocative testing. The angle was narrow under light conditions and occluded in the dark, except for the inferior quadrant where the angle was wide and the iris concave. This was reproducible in four quadrants with the use of a small UBM eye cup but not the large one. A small eye cup can indent the cornea, resulting in artifactitious angle widenening. Care must be taken when using the small eye cup not to press on the cornea.

Adult↗