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Biomedical subjects

K Inokawa

Publications and source records attributed to K Inokawa.

At least 19 recordsLinked to original sources
PubMed1996

[A case of spontaneous esophageal rupture successfully treated with a pedicled omental flap].

We experienced a case of spontaneous esophageal rupture. A 64-year-old male was admitted to the hospital with shock because of a severe epigastralgia after vomiting. We suspected spontaneous esophageal rupture by the mediastinal air and left pleural effusion of a chest X-ray film of first visit, and diagnosed it by esophagography, then operated 8 hours later the onset. On operation, following the primary closure the esophageal rupture, the pedicled omental flap was applied over the suture site. He complicated renal failure and multiple organ failure, but not leakage postoperatively. In a review of clinical cases seen in the literature, we recommend early operation and the adjunctive use of the pedicled omental flap.

Esophageal Diseases↗
PubMed1993

Primary neurilemoma of the thyroid gland: report of a case.

Neurilemoma, like other non-epithelial tumors, seldom occurs in the thyroid gland. A 57-year-old man was first referred to our hospital with an asymptomatic anterior neck tumor. A solid tumor was detected in the right lobe of the thyroid and an enucleation of the thyroid tumor was performed. The tumor was 35 x 33 x 33 mm in size, and diagnosed as Antoni A type neurilemoma. We were only able to find seven previously reported detailed cases of primary neurilemoma of the thyroid gland. A review of these cases, however, revealed that neurilemoma tends to develop in the right lobe of the thyroid gland. An operation is thus considered necessary and an enucleation of the tumor is appropriate.

Humans↗
PubMed1986

Scintiscanning demonstration of thymoma: comparative study on scintiscans using 201Tl, 67Ga and 75Se.

Thymus scintigraphy was performed using 201Tl-chloride, 67Ga-citrate and 75Se-selenomethionine on 30 thymoma patients with or without myasthenia gravis. Mass negativity was observed in 6 out of 17 (35.3 per cent) and 3 out of 13 cases (23.1 per cent), respectively. A rate of 70 per cent (21 cases out of 30) of mass positivity was observed by thymus scan using 201Tl. With regard to the relation between thymus scan and cell type, 201Tl-scan exhibited a high rate of mass positivity, regardless of the cell type while the 75Se-scan showed a trend toward mass positivity in epithelial cell predominant cases. With 201Tl, mass positivity was observed when the CPM/g ratio for tumors and blood exceeded 3.0. This trend can serve as an index for the suitability of supplementary chemo- and radiotherapies, as well as for prognosis in cases of relapse, and in those for whom excision was not complete.

Gallium Radioisotopes↗
PubMed1983

Significance of renin-angiotensin system during and after surface-induced simple hypothermia in open-heart surgery.

The present studies were performed to investigate the metabolic role of the lungs in the renin-angiotensin system under hypothermia by measuring plasma renin activity, plasma angiotensin I (A I), plasma angiotensin II (A II), plasma aldosterone and plasma angiotensin converting enzyme activity on 14 patients who underwent open-heart surgery with surface-induced simple hypothermia. In addition, dog experiments were performed, in which changes of renal blood flow and angiotensin metabolism in lungs and kidneys under hypothermia were studied in vivo. The following results were obtained: 1) During and after open-heart surgery with surface-induced simple hypothermia, the homeostasis in the renin-angiotensin system is still maintained. 2) An increase of A II may play an important role in maintaining blood pressure under hypothermia. 3) Under hypothermia, the conversion of A I to A II in the kidneys may contribute to an increase of plasma A II.

Adolescent↗
PubMed1981

Somatic and psychomotor development of children after hypothermic open-heart surgery.

One hundred and seven patients with ventricular septal defect who survived one and a half to thirteen years after hypothermic open-heart surgery were reviewed with respect to somatic, intellectual, and psychomotor development. There were no negative effects associated with deep hypothermic arrest in any of these areas. Abnormal electroencephalograms were seen in one-half the number of patients examined, but there was no close relation between the circulatory arrest period and electroencephalographic findings. CT scanning of the brain indicated that the abnormality decreased with the lapse of the time after hypothermic open-heart surgery. It would appear that hypothermic open-heart surgery with limited circulatory arrest is a useful method, providing that the circulatory arrest is not allowed to exceed a limited period. However electroencephalographic assessment suggests that postoperative cerebral abnormalities may occur more frequently than previously suspected, despite the lack of preoperative abnormalities on the electroencephalograms.

Body Height↗
PubMed1981

Inhibitory mechanisms of insulin secretion associated with hypothermic open-heart surgery.

In order to clarify the inhibitory mechanism of insulin secretion associated with open-heart surgery, the influence of insulin antagonistic hormones on insulin secretion was studied in 20 patients with congenital heart diseases undergoing open-heart surgery, under simple deep hypothermia. Despite a hyperglycemia, plasma immunoreactive insulin and C-peptide showed no change during the cooling period, while with the exception of plasma human growth hormone, dopamine-beta-hydroxylase, immunoreactive glucagon, cortisol and cyclic AMP in plasma, either showed no change, or a decrease during the cooling period. It is assumed that catecholamine, glucocorticoid and glucagon do not play an important role in the inhibitory mechanism of insulin secretion during hypothermic open-heart surgery, and a transient hypofunction of the pancreas as well as the liver and the adrenal gland is probably involved.

Blood Glucose↗
PubMed1981

Changes of kallikrein and serotonin in plasma during and after open-heart surgery.

Plasma kallikrein activity and plasma serotonin were studied during and after open-heart surgery in 15 patients with extracorporeal circulation and in 15 patients with surface-induced deep hypothermia. Following results were obtained: 1) Plasma kallikrein activity which reflects the activation of the kinin system, showed no significant change during extracorporeal circulation, and significantly increased three hours after the termination of perfusion. However, there was no significant difference in plasma kallikrein activity between the patients with and without low cardiac output syndrome (LOS). In surface-induced deep hypothermia, plasma kallikrein activity showed no significant change during and after operation. 2) Plasma serotonin significantly decreased during both extracorporeal circulation and hypothermia. Moreover, there was no significant difference in plasma serotonin between the patients with and without postoperative LOS or pulmonary hypertension. It is assumed that plasma serotonin may not play an important role in regulating blood pressure during or after open-heart surgery with either extracorporeal circulation or surface-induced deep hypothermia.

Adolescent↗