Is "wet lung" an iatrogenic syndrome? (proposal for an experimental study).
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Biomedical subjects
Publications and source records attributed to K Iriya.
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The early duodenal carcinoma is a very rare type of neoplasia, usually asymptomatic, its surgical treatment remains a controverse issue. In the present case an early duodenal carcinoma was incidentally found at the pathological specimen after a gastrectomy with BII reconstruction for a gastric adenoma unressectable by endoscopy. The patient is now alive for two years, without evidence of recurrence on follow-up.
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The sensitivity of endoscopic examinations, acid perfusion test and 24-hour esophageal pH-monitoring, were studied in patients with heartburn. Thirty six adult patients with histological esophagitis were included in this prospective study. Endoscopy showed esophageal lesion in 18/36 (sensitivity of 50%): esophagitis grade I in 10 (55.6%) and, grade II in eight (44.4%). Acid perfusion test was positive in 10/25 (sensitivity of 40%) of the patients submitted to the test. Twenty-four-hour pH-monitoring was positive in 17/29 patients (sensitivity of 58.6%): eight (61.5%) did not have esophageal lesion at endoscopy, two (25%) had esophagitis grade I and seven (87.5%) had esophagitis grade II. In the patients submitted to 24-hour pH-monitoring, a greater number or reflux episodes in orthostatic position than in supine position (P < 0.0001) was observed. The total number of reflux episodes, the most prolonged reflux and the total pH time < 4 were statistically higher in post-prandial period than during meals (P = 0.005).