Cytarabine and thioguanine therapy for acute myelomonocytic leukemia initiated in the tenth week of pregnancy (with the addition of vincristine and rubidomycin at 17 weeks) led to a short complete remission of the leukemia in a 24-year-old primigravida. This is the first case to be reported in which cytarabine was administered in the first trimester and a prostaglandin termination of pregnancy performed at 20 weeks produced an apparently normal fetus. A review of the literature suggests a slightly less than 50% chance of producing a live healthy baby if acute myelogenous leukemia is diagnosed in the first half of pregnancy, with materna mortality approaching 100% by six months postpartum. Current therapy may improve these figures.

Abortion, Therapeutic↗

PubMed1976

Advanced abdominal pregnancy with severe pre-eclampsia.

Severe pre-eclampsia leading to fetal death in advanced abdominal pregnancy is reported. Attention is drawn to the low reported incidence of pre-eclampsia in this condition and possible explanations are put forward.

Female↗

PubMed1976

Hormone patterns at the climacteric.

Explore the source record for details and available documents.

Androstenedione↗

PubMed1969

Early induction of labour in cases of rhesus iso-immunisation.

Explore the source record for details and available documents.

Cesarean Section↗