Bacillus endophthalmitis.
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Anti-Bacterial Agents↗
Biomedical subjects
K J Awan
Publications and source records attributed to K J Awan.
Three disorders occur in unusual association.
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Adult↗
The interrelationship of cataract and glaucoma.
The visual loss in a patient with cataract might actually be due to a coexistent glaucoma. This significant interrelationship of cataract and glaucoma is discussed. A thorough ophthalmic evaluation is mandatory in every case of cateract.
Aged↗
Crystals in the aqueous humor of normal eye.
An unusual and extremely rare occurrence of the free floating crystals in the aqueous humor of a structurally healthy and functionally normal eye of a 15-year-old white girl is described. The exact nature of these crystals could not be determined but their iridescent nature suggests that they might be cholesterol. This observation leads one to believe, contrary to the current concept, in the very interesting possibility of the crystal formation (or synchysis scintillans) in an apparently healthy eye.
Adolescent↗
Congenital toxoplasmosis: chances of occurrence in subsequent siblings.
Occurrence of congenital toxoplasmosis in subsequent siblings after the birth of an affected child is discussed. Toxoplasmic retinochoroiditis was found in 3 surviving siblings. The diagnosis was made by the typical fundus lesions in children, intracranial calcification in one child, and significant positive titer for toxoplasmic antibodies in all the children and the mother, who was asymptomatic. Serology for syphilis, skin tests for histoplasmosis and tuberculosis, blood studies with sedimentation rate, and chest roentgenograms were all negative in mother and all 3 children. The view that transmission of infection from mother to the fetus may result from a chronically infested uterine wall is supported and is thought to be the probable cause in the cases reported here. After the birth of one child with congenital toxoplasmosis, the parents may be reassured about the favorable prognosis of subsequent pregnancies with some reservation. However, it appears unwise to categorically refute the repetition of congenital toxoplasmosis in siblings. It is also suggested that because of possible danger of reactivation, the healed toxoplasmic chorioretinal lesions should be properly monitored if the patient is to be given corticosteroids for any other reason.
Adolescent↗
Intraepithelial epithelioma (Bowen's disease) of conjunctiva and chronic lymphocytic leukemia.
Occurrence of intraepithelial epithelioma (Bowen's disease) of the conjunctiva in a 54-year-old white man with chronic lymphocytic leukemia and bilateral labiopalatine clefting is discussed. The lesion developed slowly during 3 years following mechanical trauma to the eye. The interrelationship between trauma, Bowen's disease, and chronic lymphocytic leukemia remains obscure. It is postulated that an altered immunologic status might be responsible for neoplastic changes in the posttraumatic healing process. Intractable lesions in a patient with abnormal immunologic system or with an already proven malignancy should be studied by excisional biopsy.
Bowen's Disease↗
Arterial vascular anomalies of the retina.
The incidence of nonaneurysmal congenital anomalies of the retinal arteries was determined by ophthalmoscopic examination of the eyes of 2,100 consecutive healthy individuals whose ages ranged from 6 to 68 years. Unusual anomalies were triple branching, anomalous course, arteriolar-arterial crossing, unusual tortuosity, prepapillary loops, aberrant macular arteries, unusual supply of the optic disc, presumed total ciliary arterial supply of the retina, anomalous relationship with the central retinal vein at the optic disc, and pseudoaneurysm of a major retinal artery. Cilioretinal arteries are the commonest of the congenital vascular anomalies of the retina.
Adolescent↗
Familial polyposis and angioid streaks in the ocular fundus.
A 48-year-old white man had angioid streaks associated with familial polyposis. Although the streaks were seen only in the right eye when examined by ophthalmoscopy, a tiny angioid streak was also discovered in the apparently uninvolved left eye during fluorescein angiography.
Angioid Streaks↗
Cryotherapy in phthiriasis palpebrarum.
A 5-year-old white girl had phthiriasis palpebrarum of both upper eyelids. Excellent cooperation by the patient permitted the destruction of adult lice and the nits by cryoapplication under the slit lamp. Cryotherapy seems to be a promising method of treating phthiriasis palpebrarum in a single office visit.
Child, Preschool↗
Microhyphema.
A case of microscopic hemorrhage into the anterior chamber is described. Slit-lamp examination disclosed a steady fine stream of blood issuing from a tiny grayish bulblike microhemangioma at the pupillary border. Fluorescein biomicroscopy revealed several similar microhemangiomas on the borders of each pupil. It is presumed that minor ocular irritation, due either to poison ivy or to a menthol (0.70%) cream which the patient applied to her face, precipitated the microhyphema.
Adult↗
Association of ocular, cervical, and cardiac malformations.
Association of ocular, cervical, and cardiac anomalies is discussed. A case with severe congenital heart disease, unusual Duane's retraction syndrome, classified here as atypical typical, and Klippel-Feil anomaly is described. To alert the physicians to such an association of congenital malformations and for nosological purposes this entity may be called oculo-cervico-cardiac syndrome. Importance of the association of heart and eye abnormalities is stressed and syndromes with associated ocular and cardiac anomalies are briefly discussed.
Abnormalities, Multiple↗
Sebaceous carcinoma of the eyelid.
An unusual case of sebaceous carcinoma of the eyelid is described. Site of the lesion and noninvolvement of the lid margin or the skin suggest that it arose from meibomian glands. A complete excision and not partial biopsy of the suspected lesions is advised for histopathologic studies. It is suggested also that the specimen must be examined by an ophthalmic pathologist.
Adult↗
Hypotelorism and optic disc anomalies: an ignored ocular syndrome.
Hypotelorism, decreased interpupillary or interocular distance, deserves a wider recognition. Its association with anomalies of the optic disc is emphasized. This association appears to be a well defined ocular syndrome and may be considered another helpful clue in the differential diagnosis of the so-called pseudopapilledema from true papilledema.
Abnormalities, Multiple↗
Shrinkage of conjunctiva, Terrien's marginal degeneration, and perforation of cornea in rheumatoid arthritis.
The unusual occurrence of severe conjunctival shrinkage resembling ocular pemphigoid and bilateral Terrien's marginal degeneration of the cornea in rheumatoid arthritis is described. In less than two years the right eye was lost due to spontaneous corneal perforation and the left became totally blind because of scarring and shrinkage of the conjunctiva. A common unknown factor is speculated as an etiologic relationship between rheumatoid arthritis, ocular pemphigoid, and Terrien's marginal corneal degeneration.
Aged↗
Marcus gunn (jaw-winking) syndrome.
Association of Marcus Gunn (jaw-winking) syndrome with ipsilateral familial cleft lip occurred in a 17-year-old white boy. He had anisometropia and esotropia with amblyopia of the involved eye. Jaw-winking and blepharoptosis improved to a cosmetically acceptable extent as the child grew older.
Adolescent↗
Mikulicz's disease and Mikulicz's syndrome.
The pathogenesis, clinical manifestations, and historical development of Mikulicz's disease and Mikulicz's syndrome are given. It is recommended that the term "Mikulicz's syndrome" be dropped to avoid confusion with the rare and well defined entity "Mikulicz's disease."
Diagnosis, Differential↗
Strabismus fixus divergens and associated craniofacial anomalies.
A case of congenital strabismus fixus divergens is described. Other anomalies were vertically oval corneas, high mixed astigmatism, amblyopia, horizontal nystagmus, microcephaly, maxillary hypoplasia, micrognathia, low set large ears, and hyperostosis frontalis interna.
Exotropia↗
Indirect traumatic optic atrophy.
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Adult↗