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K J Cherney

Publications and source records attributed to K J Cherney.

3 recordsLinked to original sources
PubMed1979

Leukocyte function in granuloma annulare.

Leukocytes from patients with granuloma annulare were studied in vitro in order to detect functional abnormalities. Random migration and chemotaxis of both polymorphonuclear leukocytes and monocytes were similar in patients and controls. Preincubation of normal cells with patients' plasma did not enhance or inhibit locomotion. Phagocytosis and oxidative burst as reflected by chemiluminescence were also normal. Peripheral blood lymphocytes incorporated uridine normally with and without stimulation by the non-specific mitogen phytohaemagglutinin. These studies suggest that peripheral blood leukocyte function in patients with granuloma annulare is normal, but do not exclude a functional abnormality in tissue.

Adult↗
PubMed1979

Elevated heparin-precipitable fraction of plasma in granuloma annulare.

The levels of heparin-precipitable fraction of plasma were determined in 17 patients with granuloma annulare and 26 persons used as controls. The mean level in patients was greater than the mean level in persons used as controls (P LESS THAN .05). Patients with widespread, disseminated lesions tended to have higher levels than patients with more localized disease (P LESS THAN .15). New lesions were actively forming in two patients with widespread disease at the time of study, and levels of heparin-precipitable fraction in these patients were among the highest found. The significance of these findings and their relationship to the etiopathogenesis of granuloma annulare is speculative.

Adult↗