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Biomedical subjects

K J Cong

Publications and source records attributed to K J Cong.

15 recordsLinked to original sources
PubMed1994

[Lipid metabolism and pregnancy induced hypertension].

Lipid metabolism was studied in 30 healthy non-pregnant women, 35 normal pregnant women and 34 patients with pregnancy induced hypertension (PIH). Total cholesterol (TC), triglycerides (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), LDL-C/HDL-C ratio, and athero-sclerosis index (AI) were determined. In comparison with the non-pregnant status, lipid levels did not increased during normal mid-trimester pregnancy, but significantly increased at late trimester of normal pregnancy (P < 0.05). There was no significant difference in lipid levels between normal late pregnancy and PIH of mild and moderate degree, but TG and AI were significantly higher in cases with severe PIH. It showed that: lipid profiles in severe PIH was characterized by type IV hyperlipidemia; high lipid levels during normal late pregnancy might be a physiological phenomenon which presents a risk factor for PIH; marked increase of TG and AI in severe PIH may result in a rise of lipid peroxide (LPO).

Adult↗
PubMed1994

[Abnormal partograph in primipara with vertex presentation].

A prospective study on partograph (cross X type) was carried out in primipara with vertex presentation. There were 50 cases of dystocia in the study group and 50 cases of normal delivery in the control group. The results showed that the latent phase and active period of labor course in study group was significantly longer than the control group (P < 0.001). The speed of cervical dilation and descent of fetal presentation in the study group was marked slower than the control group (P < 0.001). The rate of postpartum hemorrhage, total time of labor, operative delivery rate and neonatal asphyxia rate in the study group were significantly higher than the control group (P < 0.001). After active management 38 cases in the abnormal group were delivered vaginally. It suggested that the use of partography is very important in revealing abnormal labor course and detection of dystocia, guiding the management of labor.

Adult↗
PubMed1994

[Complication of ascites in pregnancy-induced hypertension].

Twenty three pregnancy-induced hypertension (PIH) patients with ascites were treated in Beijing Obstetrics and Gynecology Hospital from Jan. 1981 to April 1992. The incidence of ascites in PIH was 1.9/1000 in total in this study, and 21.6/1000 in severe PIH. Clinical manifestations showed an early onset of PIH at 29.4 +/- 4.8 weeks, and ascites occurred at 32.4 +/- 7.4 weeks. There were 18 cases out of 23 who had no routine antenatal care, all of them had complications with IUGR. Laboratory studies: ascites showed transudate in all of them except one with chronic nephritis exhibiting milky appearance. 10% of patients had abnormal complete blood count (CBC) and 13%-17% abnormal electrolytes. 17.0% of the patients had GPT > 30IU, 21.0% urea nitrogen > 35 g/L, 95.7% had plasma albumin < 35 g/L. The ratio of A/G was < 1.5 in all patients. We conclude that once PIH was 1.5 in all patients. We conclude that once PIH was complicated by ascites, it can not be cured by active treatment. It is an indication for termination of pregnancy. After delivery the ascites and pleural effusion gradually disappeared in 2 weeks. Perinatal mortality rate was as high as 42.1% because of premature induced labor and IUGR.

Adult↗
PubMed1993

[Calcium and pregnancy induced hypertension].

In this paper the relationship between calcium and pregnancy induced hypertension (PIH) was prospectively studied. 150 normal pregnant women were divided into 3 groups: group A with supplement of calcium element 1g/day, group B 2g/day and group C with no calcium supplement. 8%, 4% and 18% of each group had developed PIH respectively. It seems that supplement of 2 gram calcium per day gave the best result. Furthermore the study was expanded: 200 cases with supplement of calcium element 2 g/day from 20-28th week of pregnancy, another 200 pregnant women without calcium supplement. The occurrence of PIH was 7.5% and 16.5% respectively. There was no adverse effect with 2 g calcium supplement. The metabolism of calcium in normal pregnancy and PIH was discussed. Supplement of calcium during pregnancy may benefit by reduction of PIH incidence.

Calcium↗
PubMed1992

[Hemodynamic effects of antihypertensive drugs on pregnancy-induced hypertension].

Aiming to select a proper kind of antihypertensive drug for mild and moderate pregnancy-induced hypertension (PIH), 30 patients with PIH were examined by using noninvasive cardiovascular detector TP-CBS. The basic hemodynamic parameters included mean artery pressure (MAP) Kpa, heart rate (HR) bpm, cardiac index (CI) L min-1/m2 and total peripheral resistance (TPR) PRU. The 30 cases were divided into 6 groups with 5 each to take a single dose of prazoxin, phentolamine, methyldopa, captopril, nifedipine and aminophylline respectively. Hemodynamic parameters were examined consecutively every 30 minutes for 4 hours after ingesting the above drugs. The results showed that all the 6 medicines had effects of lowering MAP and TPR without change of cardiac output. Nevertheless, viewing from the effect of lowering blood pressure, change of pulse rate, time of action and incidence of side effects, we considered that nifedipine is superior to the other 5 and can be preferably recommended at outpatient clinic.

Antihypertensive Agents↗
PubMed1992

[Hemodynamic surveillance in pregnancy induced hypertension during volume expansion therapy].

Hemodynamic parameters were studied in 80 cases of pregnancy induced hypertension (PIH) using noninvasive cardiovascular detector (TP-CBS). Women were categorized into 3 kinds of hemodynamic patterns: (1) normal cardiac output, 45 cases, cardiac index (CI) = 2.5-4 L.min-1/m2; (2) high cardiac output, 10 cases, CI greater than 4 L.min-1/m2; (3) low cardiac output, CI less than 4 L.min-1/m2, 25 cases (31.5%). Ten cases in each category were selected for test after volume expansion therapy. MAP decreased in varying degrees. CI showed marked increase in the low cardiac output group, but decreased to normal in the high output group. The monitoring criteria for protecting against pulmonary edema during volume expansion therapy were discussed.

Adult↗
PubMed1990

[Puerperal thrombophlebitis].

Thirty-eight cases of puerperal thrombophlebitis were reported. The incidence was 0.36% for the 1960s and 0.38% for the 1970s. During 1980s, it was reduced to 0.11%. However, the severity of the disease remained unimproved. Pulmonary and cerebral embolism occurred each in one case. Cesarean section was found to be associated with a 3-19 times increase of risk of developing puerperal thrombophlebitis as compared with vaginal delivery. The pathophysiological changes, diagnostic methods, treatment and prevention are discussed.

Adult↗
PubMed1989

[Predicting pregnancy-induced hypertension by radial arterial pulse waves].

This study was carried on several methods used in predicting of pregnancy induced hypertension (PIH). Radial arterial pulse wave was found to give a predictive rate up to 85.7%, higher than that by mean arterial pressure in the second trimester of pregnancy or roll-over test. Thereafter, addition of cardio-parameters, peripheral resistance and pulse wave coefficient K value yielded more accurate predicting effect in 120 cases. By recognizing the subclinical phase and giving mothers to be advises on daily life we were able to decrease the incidence of PIH from 18.8% to 9.2%.

Female↗