Biomedical subjects

K J Goitein

Publications and source records attributed to K J Goitein.

22 records · Page 2Linked to original sources

PubMed1982

Percutaneous placement of subdural catheter for measurement of intracranial pressure in small children.

Broadening indications for continuous monitoring of intracranial pressure (ICP) in neonates and small infants have created increasing interest in modalities which would permit measurement of ICP safely and accurately. Such monitoring allows rapid initiation of treatment when increased ICP is observed. Using a new technique for subdural tap, the authors inserted percutaneously a subdural catheter in 9 patients, 5 had cerebral ischemia, and 4 had CNS infection. These patients exhibited marked changes in ICP during the course of their disease, often within a short time period. Continuous monitoring made it possible to initiate treatment immediately at the onset of increased ICP. In this series, no complication related to the subdural catheter placement was observed., This technique proved to be highly accurate, effective, safe, and very easy to perform.

Brain Edema↗

PubMed1982

Incidence of convulsions and encephalopathy in childhood Shigella infections. Survey of 117 hospitalized patients.

Of 117 children ill enough to be hospitalized with Shigella gastroenteritis, 53 per cent had neurologic symptoms, the majority during the onset of high fever: 11 per cent had convulsions alone, 22 per cent had encephalopathy alone, and 20 per cent had convulsions and encephalopathy. The neurologic manifestations preceded the gastrointestinal symptoms in one fourth of the patients. Shigella sonnei was the predominant organism found in this study, especially in patients with neurologic symptoms.

Age Factors↗

PubMed1980

Electrocardiogram in double chamber right ventricle.

Thirty patients with a double chamber right ventricle were seen during a 7 year period. The majority of patients had associated cardiac anomalies, most commonly a ventricular septal defect. In this series, as in others, the history, clinical examination, chest roentgenogram and echocardiogram were inconclusive for diagnosing double chamber right ventricle. Symptoms were generally related to the severity of the associated anomalies. In 40 percent of the patients reviewed, upright T waves were found in lead V3R as the only electrocardiographic finding suggestive of right ventricular hypertrophy. Because upright T waves in lead V3R in the absence of other evidence of right ventricular hypertrophy are not commonly seen in patients with an isolated ventricular septal defect or a defect associated with other forms of right ventricular outflow obstruction, this finding should alert the cardiologist to the possibility of the presence of double chamber right ventricle prior to cardiac catheterization.

Adolescent↗

PubMedDate not supplied

Prolonged electrocerebral silent barbiturate coma in intractable seizure disorders.

Barbiturate coma (BC) is a known modality for terminating resistant convulsive status epilepticus. It is usually applied until seizure activity ends. We recently adopted a modified protocol of prolonged, electrocerebral silent BC to treat patients with chronic seizure activity resistant to multiple regimens of antiepileptic drugs. Four patients, aged 4 months to 10 years, with long-standing intractable generalized seizures were treated. Seizure frequency ranged from one to two to numerous times per day. Following BC, one patient has been seizure free during 8 months of follow-up, and another has had only two seizures in 18 months. A 4-month-old infant was seizure-free for 2 weeks after BC and then died from underlying CNS disease. A 10-year-old girl died during BC from shock and hyperpyrexia. The results obtained in our patients indicate that prolonged electrocerebral silent BC may exert a beneficial long-term effect in treatment of intractable seizure disorders. This procedure might also be beneficial in other forms of epilepsy.

Child↗