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Biomedical subjects

K J Hoffer

Publications and source records attributed to K J Hoffer.

At least 55 records · Page 3Linked to original sources

Effects of extracapsular implant techniques on endothelial density.

A comparison of surgical techniques with phacoemulsification showed that changing from anterior to posterior chamber emulsification afforded a drop in endothelial cell loss from 24.6% to 12.5%. Implantation of a Shearing posterior chamber lens instead of a Binkhorst two-loop iridocapsular lens did not decrease the cell loss using anterior chamber emulsification. Cell loss was approximately 25% in both groups. The addition of sodium hyaluronate (Healon) to the procedure of posterior chamber emulsification and implantation of a Shearing lens did not raise or lower the cell loss noted when using air alone. However, with the technique described whereby most of the sodium hyaluronate is irrigated from the eye at the end of the procedure, there was no increase in intraocular pressure postoperatively and no untoward effects. Posterior chamber emulsification seems mandatory, and though sodium hyaluronate did not improve cell loss, its use as a precaution seems to be completely safe when correct procedures are followed.

Cataract Extraction↗

Accuracy of ultrasound intraocular lens calculation.

A review of the literature was made to evaluate the prediction accuracy of intraocular lens calculations. A uniform standard formula (percentage +/- 1.0 diopter/percentage +/- 2.0 D/range of error) for reporting accuracy was used to evaluate the accuracy of reports in the literature, as well as the accuracy of an ultrasound unit (Kretz 7100 MA), the HOffer formula, use of a standard 3.5-mm anterior chamber depth, and addition of a retinal thickness factor to the measured ultrasound axial length. The appropriateness of technicians performing this procedure also was evaluated. Results of previous studies show that the use of another ultrasound unit (Sonometrics DBR) and Binkhorst's formula is the least clinically accurate method.

Eye↗

Pathologic examination of a J-loop posterior chamber intraocular lens in the ciliary sulcus.

A Shearing J-loop posterior chamber intraocular lens was implanted into an eye after an extracapsular cataract extraction. The loops were deliberately placed in the ciliary sulcus between the iris root and the ciliary processes. The patient died 11 months after surgery and the eye was obtained for pathologic study. The complete lack of inflammation in the uveal tissue where the loops of the intraocular lens had rested confirmed the benign postoperative course of this eye.

Aged↗

UCLA clinical trial of radial keratotomy. Preliminary report.

A clinical trail of radial keratotomy ws begun under a strict research protocol at the Jules Stein Eye Institute in November 1979. The results for the first 52 eyes undergoing radial keratotomy are reported three months after surgery. Preoperatively uncorrected visual acuity was less than 20/200 in all 52 eyes. and postoperative visual acuity was less than 20/200 in 11 eyes (21%). Three months postoperatively, uncorrected visual acuity was 20/40 or better in 27 eyes (52%) and 20/20 or better in 13 eyes (25%). Postoperatively the best-corrected visual acuity decreased in 10 eyes (20%), but maximum decrease in any eye was one line of snellen letters. Preoperatively mean refractive error was -4.9 (/+-2.2) diopters, and postoperatively the mean decrease in myopia was 3.4 (/+-2.2) diopters. Postoperatively 13 eyes (25%) had a hyperopic refractive error of +0.25 to +3.25 diopters, but all of these eyes were able to accommodate and obtain 20/20 visual acuity without glasses. Postoperatively there was no statistically significant change in axial length, anterior chamber depth, or scleral rigidity, but there was a mean corneal endothelial cell loss of 10% (P = 0.0002). Decrease in myopia achieved by radial keratotomy did not correlate with the steepness of corneal curvature, corneal diameter, or scleral rigidity. Three months after surgery, significant symptoms of glare were present in 10 eyes (20%0, and annoying variable visual acuity was noted in five eyes (10%).

Adult↗

Normal endothelial cell count range.

It was the purpose of this study to determine whether age could be used to predict central endothelial cell count in preoperative cataract patients aged 40 to 90. Three separate series of cell counts on a total of almost 3,000 eyes were performed and analyzed regarding age relationship. Although statistically endothelial cell count appears to decrease with age, the decrease is so small that a large range of cell counts was noted for each age. The results of this study indicate that age is not useful in estimating endothelial cell count in this population.

Adult↗

Vertical endothelial cell disparity.

Endothelial cell counts were performed postoperatively in superior, central, and inferior areas of the cornea in 59 patients. No regional differences were found in a series of 23 preoperative control cataract eyes. A definite, large density disparity was noted in 58 of the 59 postoperative corneas studied. Disparity was high nine years as well as two weeks postoperatively. These data indicated that necessity for accuracy of positioning in postoperative comparison studies and the necessity for regional cell counts before secondary surgical procedures.

Adult↗