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Biomedical subjects

K J Jodczyk

Publications and source records attributed to K J Jodczyk.

17 recordsLinked to original sources
PubMed1991

Human stored blood inositol phospholipids.

The total amount of phospholipids of the stored blood erythrocytes does not change during the first week of storage. After the second and the third week of storage the changes are only insignificant. During the fourth week this amount decreases by 25%. Detailed analysis of inositol phospholipids shows that balance of the phosphorylation-dephosphorylation cycle is shifted towards dephosphorylation. The decrease in phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) is accompanied by the increase in phosphatidylinositol-4-phosphate (PtdIns-4-P) and phosphatidylinositol (PtdIns). The total amount of inositol phospholipids does not change. The increase in PtdIns-4-P is accompanied by the appearance of echinoidal forms of erythrocytes. The results of this study suggest that PtdIns-4-P can be considered as one of the important factors which determine the shape of erythrocytes.

Adult↗
PubMed1991

[Influence of alcohol on morphological changes of the laryngeal and pharyngeal mucosa].

The long term intake of the ethyl alcohol by rats caused the morphologic changes of plano-epithelial and subepithelial layer of the larynx mucosa. The most expressed lesions were the disconnection of the epithelial structures and its taking into pieces. The changes were accentuated by longer alcohol intake, especially in morphology, size and color.

Alcoholism↗
PubMed1990

Effect of lathyrogen on collagen of methylcholanthrene-induced sarcoma of rat.

Since the lathyrogen beta-aminopropionitrile is known to affect the fibrogenic and physical properties of collagen polymers, we have examined its effects on collagenous components of methylcholanthrene-induced fibrosarcoma in rat. Lathyrogen treatment reduced total collagen content of tumours from approximately 17 to 12 mg collagen/g tissue. It also proportionately increased the solubility of specific collagen fractions, the summation of all extractable solubilized collagens reflecting 37 and 67% of total collagen content for control and lathyric tumours, respectively. Although lathyrogen had no significant effect on the growth and overall size of fibrosarcoma, histological studies confirmed that changes had occurred to appearance and distribution of collagenous components of extracellular matrix.

Aminopropionitrile↗
PubMed1987

Prolyl hydroxylase activity as an index of liver damage induced by ethanol.

It was found that chronic intoxication of rats with ethanol results in an increase of prolyl hydroxylase activity in liver and serum of the experimental animals. The increase of enzyme activity precedes the morphological symptoms of liver damage. The possibility arises that the assay of prolyl hydroxylase in serum or in liver biopsy samples could be useful for the diagnosis of the tendency of some individuals to develop liver cirrhosis induced by ethanol.

Alcoholism↗
PubMed1987

[The healing process after implantation of bilateral velour vascular prostheses of the Dallon type into the abdominal aorta of dogs].

In the defect of the resected part of the abdominal aorta in 36 dogs vascular prostheses were implanted. The prostheses were bilaterally veloured of the Dallon type, produced in Poland. The process of healing of the vascular prostheses proceeded two stages. In the first stage the structures were produced. In the second stage the connective tissue developed and endothelium cells on the surface of the newly produced internal layer. The analysis of morphological test results allows us to state that in the process of reconstruction of the arteries we have to the with a certain balance in the regenerative and reperative processes.

Animals↗
PubMed1979

[Comparative studies on Trichomonas vaginalis in the scanning electron microscope].

Different strains of Trichomonas vaginalis isolated from the vagina of women with trichomoniasis were used in these investigations. The cultures were carried out on modified CPLM and Roiron media. Individuals at the highest phase of logarithmic growth underwent the observation. Preparations to be evaluated in scanning electron microscope ( JEOL - JSM -S1) were made from a condensed culture containing 500,000 individuals per ml. Each time, microscopic pictures obtained after washing, demucination and various fixation procedures and after lyophylisation were compared to each other. The pictures obtained from smears taken from the vagina of women with trichomoniasis were compared, too. Special attention was paid to the behaviour of the surface and motion organelles of the parasite.

Biometry↗