PubMed Health⌕ Search

Biomedical subjects

K J Trimmer

Publications and source records attributed to K J Trimmer.

4 recordsLinked to original sources
PubMed1994

Prenatal diagnosis of the Klippel-Trenaunay-Weber syndrome.

The Klippel-Trenaunay-Weber syndrome is a complex developmental disorder of the vascular and skeletal systems. While many features of the syndrome are congenital, it has not been diagnosed often before birth. This paper describes a case of Klippel-Trenaunay-Weber syndrome diagnosed at 19 weeks' gestation on the basis of sonographic findings and family history. The clinical variability of the syndrome is emphasized and the importance of family history in differential diagnosis is stressed.

Adult↗
PubMed1991

"Meconiumcrit" and birth asphyxia.

Determination of the percent by volume of the solid component of meconium (the "meconiumcrit") provides a more objective method of characterizing the type of meconium. In a study of 106 women with meconium-stained amniotic fluid, 61 (58%) had thin meconium, 36 (34%) had moderate meconium, and nine (8%) had thick meconium. There was no correlation between the type of meconium and newborn acidemia (umbilical artery pH, less than 7.20)--13%, 19%, and 11%, respectively. None of the newborns with either thin or thick meconium had 1-minute Apgar scores of less than or equal to 3 and only two with moderate meconium had such Apgar scores; none had an Apgar score of less than or equal to 3 at 5 minutes. None of the newborns with thin or moderate meconium had meconium aspiration syndrome, although two of nine infants with thick meconium did have meconium aspiration syndrome. All newborns subsequently did well and left the hospital in good condition. There would appear to be no correlation between the consistency of meconium and recently reported criteria for defining birth asphyxia.

Apgar Score↗
PubMed1990

Observations on the cause of oligohydramnios in prolonged pregnancy.

There is increasing evidence that implicates reduced amnionic fluid volume as a major determinant of fetal risk in prolonged pregnancy. We sought to determine whether reduced fetal urine production might be associated with oligohydramnios in pregnancies that reach 42 weeks or more. Ultrasonographic measurements of the fetal bladder were obtained every 2 to 5 minutes for 1 hour in 38 gestations verified to be at least 42 weeks. Oligohydramnios was present in eight of the prolonged pregnancies. Similar measurements were performed in 15 normal pregnancies delivered by elective repeat cesarean section between 38 and 40 weeks' gestation. Hourly fetal urine production rates were calculated with sequential bladder volume measurements. The result of this investigation suggest that diminished fetal urine production is associated with oligohydramnios in prolonged pregnancy. The mechanism by which fetal urine production is reduced in prolonged pregnancy remains unknown. A likely possibility is reduced fetal swallowing because of already diminished amnionic fluid volume, the latter a result of placental senescence.

Chi-Square Distribution↗