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K Jamal

Publications and source records attributed to K Jamal.

6 recordsLinked to original sources
PubMed1997

Outcome of abruptio placentae in normotensive and hypertensive patients in Aga Khan University Hospital, Pakistan.

The aim of our study was to compare the perinatal and maternal outcome in hypertensive women experiencing abruptio placentae with that of normotensive women. We hypothesized that hypertensive women experiencing abruptio had a less favorable outcome than the normotensive women. Ours was a retrospective cohort study, in which the outcome of 33 hypertensive women with abruptio was compared with 138 normotensive women experiencing abruptio placentae. Our results indicate that although higher number of hypertensive women with abruptio had a past history of hypertension and were more likely to have diabetes (p = 0.05) there was no difference found in the grades of abruption or in any other antenatal complications between the 2 groups. The hypertensive women were also more likely to undergo cesarean section. We did not find any difference in the neonatal outcome. Therefore, we conclude that there is no difference in the maternal and perinatal outcome between the hypertensive and normotensive women experiencing abruptio.

Abruptio Placentae↗
PubMed1990

Cor pulmonale: correlation with central airway lesions, peripheral airway lesions, emphysema, and control of breathing.

We have analyzed the heart and lung findings in 31 patients in the National Institutes of Health (NIH) Nocturnal Oxygen Therapy Trial (NOTT) with particular emphasis on cor pulmonale. Increased right ventricular weight was related to decreased bronchiolar diameter, decreased ratio of bronchiolar diameter to external arterial diameter, and an increased proportion of airways less than 400 microns in diameter. No relationship was found between the severity of emphysema, mucous gland enlargement, peripheral airway mucous plugging, or other measurement of central and peripheral airways. Patients with right ventricles weighing more than 100 g had higher pulmonary artery pressures at rest and higher arterial CO2 levels than those weighing 100 g or less. When the patients were divided into Types A, B, and X according to Burrows' criteria, those with Type X had a higher volume proportion of mucous glands; type B were intermediate; and Type A had the smallest. The amount of bronchial muscle was less in Type B patients than in Type A, and right ventricles weighted less in Type A patients than in Type B. Hypoxic ventilatory drive was lower in Type B patients than in Type A. Absolute right ventricular weight appeared to be a better measurement of right ventricular enlargement than relative right ventricular weight in the NIH NOTT patients. We conclude that right ventricular weight in patients with hypoxic chronic airflow obstruction (CAO) is related to airway narrowing, and that the Type B syndrome is associated with decreased ventilatory drive.

Aged↗
PubMed1984

Chronic bronchitis. Correlation of morphologic findings to sputum production and flow rates.

We have assessed bronchial mucous gland size in a group of 26 patients with severe chronic air-flow obstruction and hypoxemia from the NIH Nocturnal Oxygen Therapy Trial. These patients had their sputum volume assessed at least 4 times when free from exacerbations. Mucous gland size was assessed by the gland/wall ratio (Reid Index), by absolute gland area, and by the volume proportion of glands. The volume of sputum produced was significantly related to the volume proportion of mucous glands (Rho = 0.53, p less than 0.01) and to the absolute gland area (Rho = 0.49, p less than 0.05), but not to the Reid Index, (Rho = 0.35, p greater than 0.05). Volume proportion of glands can be easily and quickly measured using a computer-assisted digitizer, and it is the method of choice for measuring mucous gland size in this series. Neither the Reid Index nor the volume proportion of glands was related to the forced expiratory volume in one second (FEV1), and the measurements were not significantly related to each other. The amount of sputum produced was not related significantly to the FEV1 (Rho = 0.26, p greater than 0.05).

Aged↗
PubMed1978

Radioimmunoassay of norethindrone : serum levels of norethindrone in lactating women after insertion of a single Silastic implant releasing norethindrone acetate.

A specific radioimmunoassay was developed for the estimation of norethindrone levels in the serum of lactating women. A conjugate of norethindrone-3-BSA was synthesized and antiserum raised against it in rabbits. The antiserum showed high affinity (1.5 x 10(9)M/L) and titer and was specific. The sensitivity of the assay was 125 pg/ml serum. Serum levels of norethindrone were estimated in 25 lactating women, inserted with subdermal implant releasing about 150 ug of norethindrone acetate daily. The norethindrone levels were initially high in the first two months. From there onwards the levels of norethindrone remained constant with an average value of 1.0 ng/ml up to six months. These values were comparable to those obtained in non-lactating women. Thus, lactation does not seem to alter or affect the release of norethindrone acetate from the subdermal implant or its metabolism.

Animals↗
PubMedDate not supplied

[Bowel intussusception on the child: clinical therapeutical study].

Intussusceptions is the most common cause of bowel obstruction in children between 5 months and 1 year of age. Intussusceptions occurs when a portion of the bowel folds like a telescope, with one segment slipping inside another segment. This study refers to a group of 72 children, with intussusceptions diagnosis between 1975-2000 in our clinic. The authors are also analyzing these cases from the point of view of frequency on years, seasons, age, sex, residence, clinical forms, time since the intussusceptions occurred until the treatment begun.

Child, Preschool↗