Biomedical subjects
Publications and source records attributed to K K Monakhov.
EEG patterns (neurofunctional systems) characteristic of certain mental states are presented from the standpoint of theoretic ideas of these patterns as neurofunctional programs of brain activity. Approaches for studying the structure of these programs are discussed.
Neurophysiological studies in psychiatry have two trends: study of the mechanisms of normal and abnormal brain actvity and the use of the neurophysiological techniques to diagnose brain function in different mental pathology. The essential progress of both trends is based on the wide use of computers and mathematical analysis during recent decade. The drawback of the present state of clinical neurophysiology is its inadequate interrelation with the trends and concepts of experimental neurophysiology.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The task of the study was to determine the influence of emotional-motivational sphere on the phenomenon of out-of-logic mental activity. An accepted in laboratory model of recognition of concealed image in double image pictures was used. The electrical activity, recorded was analyzed by means of the method of computation of coefficient of community, elaborated in the laboratory, the results were presented in the from of stereometric map. The obtained results testify to the fact that emotional-motivational processes influence the mechanism of out-of-logic form of making solution; at out-of-logic form of making solution subjective evaluation of results dominates, what is reflected in the character of spatial distribution of coefficient of community.
The aim of the study was an attempt to record neurophysiological processes connected with the mechanism of subconscious brain activity. Created in the laboratory method of construction of a topographical map of electrical processes interactions in 24 recorded points was applied. The obtained data testify that identification of evident and latent images in "double image pictures" is accompanied by similar relief of topomaps of interactions. Effect of "sudden vision" of latent image in a manner of "insight" is gradually prepared neurophysiologically, but is not realized by the subject and only at the last stage reaches the consciousness and is verbalized.
Eight subjects were studied by the method of topographic mapping of interconnection characteristics of the human brain electrical activity in the process of recognition of visual images. The method used in our studies differs from others by the fact that properties of the processes interconnections are mapped but not the characteristics of the very processes. Under recognition of images the relief of topographic map of interconnections of cortical electrical processes increases in the right and decreases in the left frontal areas. Thus both hemispheres participate in this process. The hypothesis is suggested about two types of spatial synchronization: of similar electrical activity and of the activity differentiated in the brain sections. The developed method proved to be informative for the studied structure of spatial-temporal organization of the human brain electrical activity.
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The electroencephalographic reactions to stelazine, aminazine and haloperidol were studied by the methods of multifactor and multidiscriminant analyses. The specific features of pharmacogenic spatial reorganization of the EEG were revealed for every neuroleptic which made it possible to recognize the drugs in 90.9, 88.9 and 82.9% of cases, respectively.
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Methods of factorial and discriminant analysis were used for the analysis of the electroencephalographic reaction to gamonil and damilen. Specific features of EEG spatial reorganization were revealed for each of the thymoleptics which made it possible to recognize correctly the drugs in 87.5 and 92.3% of cases, respectively.
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