Biomedical subjects
Publications and source records attributed to K K Pandey.
A rare case of birth injury having intrauterine complete perineal tear is presented. Defunctioning sigmoid colostomy was undertaken because of bad perineal condition. The baby died of Pseudomonas septicemia on the 15th day before definitive surgical procedure could be undertaken.
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The technique of peroral pneumocolon (POPC) has been found to be simple and easy to obtain excellent double contrast visualization of the distal ileum and proximal colon. Thirty-four patients were subjected to the POPC examination of which 29 had undergone prior barium meal follow through studies. In 86.2% of these cases POPC was found to be superior as compared to conventional studies. In 5 patients who could not retain Ba-enema, POPC was performed as first line of investigation with 100% efficacy.
Gastric bleeding from stress ulcers in acutely sick infants frequently signals impending mortality. This study was carried out to evaluate the efficacy of cimetidine in preventing and treating stress ulcers in such neonates. One hundred babies were included in this study. Out of this, 32 babies were given prophylactic cimetidine and 68 neonates acted as controls. It was observed that the babies on prophylactic cimetidine fared better than controls. In the second part of study, 77 neonates with clinical evidence of hemorrhage were included, 43 were put on cimetidine and 34 acted as controls. It was observed that babies on cimetidine therapy showed a better response. The gastric bleeding stopped earlier, and more babies responded favourably to this therapy. Use of cimetidine in stress induced bleeding in high risk neonates is recommended.
The role of half strength, double volume milk feeds for initiating feeding in preterm newborn infants was evaluated. Thirty eight premature infants were included in the study and divided into Groups A and B having 20 and 18 babies, respectively. Group A babies were fed half strength (10 cal/oz) formula feeds but the volume was doubled, while Group B babies were fed full strength formula feeds (20 cal/oz) with standard volume. A pre-set schedule was evolved for feed increments in the two groups. The amount of feeds was increased daily till a volume of 150 ml/kg/day was reached. The end point of the study was achieved when the caloric intake became 100 cal/kg/day. It was observed that Group A babies attained enteral energy intake of 100 cals/kg/day much earlier and experienced lesser complications, viz., persistent gastric aspirate and abdominal distension. They required intravenous supplementation for a shorter duration thus reducing the associated complications.
During a seven year period (1981-87), 53 cases of typhoid fever in children below five years were seen. This accounted for 13.5% of all typhoid admission in pediatrics during the above period. Predominant symptoms were fever (100%), vomiting (52.8%), diarrhea (30.2%) and anorexia (24.5%). Chills and rigor associated with fever was noticed in 38% of the children. Salmonella typhi was isolated from blood in 22 of 53 (41.7%) cases. A significant finding on peripheral smear was eosinopenia (86.8%). Complications like endotoxic shock, enteric encephalopathy and gastrointestinal hemorrhage were noticed in only few cases (7.6%). There were no deaths.
We report a case of bilateral ureteropelvic junction obstruction associated with bilateral stones, one of which was large. An Anderson-Hynes operation was performed on both sides, the stones were removed and the patient became asymptomatic. To our knowledge the stone in our case is the largest and heaviest ever to be described in the literature.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Perinatal risk factors and bacteriological profile of conjunctivitis were studied among 245 newborns delivered at JIPMER Hospital between July 1986 and June 1988. Maternal and neonatal factors like lack of antenatal care, presence of adverse intrapartum factors, operative deliveries, birth asphyxia, pre-maturity and prolonged hospital stay significantly increased the chances of developing conjunctivitis (P less than 0.001). Bacteria were recovered from 163 (66.5%) cases. Staphylococcus was the commonest pathogenic bacteria isolated, followed by Pseudomonas aeruginosa and Klebsiella pneumoniae. Neisseria gonorrhoeae was isolated in only one case. Most of the organisms showed in vitro sensitivity to chloramphenicol, gentamycin and tetracycline. All the cases responded to topical chloramphenicol except three which required systemic antibiotics. No complications were observed. The identification and appropriate management of high risk pregnancies with minimal hospital stay can reduce the incidence of neonatal conjunctivitis.