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Biomedical subjects

K K Sinha

Publications and source records attributed to K K Sinha.

18 recordsLinked to original sources
PubMed1992

Inhibition of aflatoxin production & growth of Aspergillus flavus by eugenol & onion & garlic extracts.

Efficacy of natural non-toxic materials including extracts of onion and garlic as well as eugenol was tested against aflatoxin production by A. flavus in liquid SMKY medium and in maize grains. Maximum inhibition in the mycelial growth occurred with garlic extract (61.94%), whereas inhibition of aflatoxin production was highest (60.44%) due to onion extract. Eugenol was most suitable for inhibiting aflatoxin production (60.35%) on maize grains.

Aflatoxins↗
PubMed1988

Aflatoxin contamination of some common drug plants.

This paper deals with the natural occurrence of aflatoxins in some common drug plants collected from storehouses in Bihar, India. Of 15 samples analyzed, 14 were aflatoxin positive. The highest level of aflatoxin contamination was detected in the seeds of Piper nigrum (1.20 micrograms/g), followed by the level detected in the seeds of Mucuna prurita (1.16 micrograms/g), and the lowest level was detected in the bark of Acacia catechu (0.09 micrograms/g). Of 158 isolates of Aspergillus flavus obtained from as many samples of drug plants, 49 were found to be toxigenic. The amount of aflatoxin B1 elaborated by the toxigenic isolates was in the range of 0.86 to 5.24 micrograms/ml of culture filtrate.

Aflatoxins↗
PubMed1987

Aflatoxin contamination of maize in flooded areas of Bhagalpur, India.

Maize in flood-affected areas in the Bhagalpur district of India in 1985 demonstrated heavy infestations of Aspergillus flavus and aflatoxins. Sixty samples collected from various field lots were positive in the bright greenish yellow fluorescence test. However, only 42 of those samples were found to be contaminated with deleterious levels of aflatoxins. Factors affecting aflatoxin contamination are discussed.

Aflatoxins↗
PubMed1985

Tuberous sclerosis.

Explore the source record for details and available documents.

Child, Preschool↗
PubMedDate not supplied

Incidence of mycotoxins in maize grains in Bihar State, India.

A regular survey of some maize-growing areas of Bihar state, India, for three consecutive years (September 1984 to September 1986) revealed heavy infestations of mycotoxin-producing fungi with different maize samples. Aflatoxin-producing fungi had the highest frequency of occurrence in all the cases and aflatoxins were the most common mycotoxins elaborated by these fungi. Maize samples of the Kharif crop had a greater incidence of aflatoxins (47%) than the samples of rabi crop (17%). Stored maize grains also had a high incidence of aflatoxins (43%). Most of the contaminated samples contained aflatoxins at levels above 20 micrograms/kg.

Aflatoxins↗
PubMedDate not supplied

Monitoring and identification of aflatoxins in wheat, gram and maize flours in Bihar state (India).

The occurrence of aflatoxins in some common food commodities: wheat, gram and maize flours is reported. Of the total 416 collections during three years (1987-1989) 162 were recorded to be aflatoxin-positive. The incidence of aflatoxins was maximum in the samples of 1987. Most of the contaminated samples contained aflatoxins at levels above 20 micrograms/kg. The environmental conditions and traditional agronomic and storage practices relating to aflatoxin incidence are discussed.

Aflatoxins↗
PubMedDate not supplied

Vitamin C status, glutathione and histamine in gastric carcinoma, tuberculous enteritis and non-specific ulcerative colitis.

Studies were conducted to evaluate the blood levels of ascorbic acid, dehydroascorbic acid, glutathione, and histamine in patients with gastric carcinoma, tuberculous enteritis and non-specific ulcerative colitis. Leucocyte ascorbic acid, urinary excretion of total ascorbic acid and ascorbic acid saturation test were also carried out in order to assess the ascorbic acid status of these patients. It was observed that the plasma and leucocyte content of ascorbic acid was significantly lower with markedly decreased urinary excretion in these patients. Further urinary excretion of ascorbic acid after a test dose was also found to be subnormal. Decreased levels of glutathione and significantly higher levels of histamine reflect an overall reducing status of the body is markedly deranged.

Ascorbic Acid↗