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Biomedical subjects

K Kaden

Publications and source records attributed to K Kaden.

12 recordsLinked to original sources
PubMed1987

Thyroid lid surgery.

A retrospective study of 58 thyroid patients undergoing eyelid surgery for thyroid related lid malposition is reported. A treatment strategy is suggested, based on the results of this experience. The following points are stressed: (1) The importance of recognising and relieving the inferior rectus tethering component of upper lid retraction when present. (2) The usefulness of a scleral graft in lower lid retractor recession. (3) The inadequacy of lateral tarsorrhaphy in relieving lid retraction but its value in camouflage.

Adult↗
PubMed1986

Normal values and membrane markers of theophylline-sensitive and theophylline-resistant human T-lymphocytes.

In 32 healthy adults between 20 and 50 years, the number of theophylline-resistant T-lymphocytes (T-res) was determined to be 51 +/- 4% or 1,161 +/- 326 per microliter, and that of theophylline-sensitive T-lymphocytes (T-sens), 11 +/- 2% or 252 +/- 95.--The decrease in number of rosette-forming cells after incubation with 1 mM theophylline was not caused by reduced vitality (51Cr-release test). The testing of various theophylline concentrations (1, 3, 5, and 10 mM) did not result in a changed count of T-sens. By a variation of the lymphocyte: sheep erythrocyte ratio and of incubation temperature it was found that T-sens possess high-affine and T-res low-affine receptors for sheep erythrocytes. While about 30% of the cells of both subpopulations proved to have Fc-IgM-receptors, among T-sens a significantly higher number of cells carried Fc-IgG-receptors than among T-res (29% vs. 10%).

Adult↗
PubMed1986

[Longitudinal studies in children with pyelonephritis and glomerulonephritis with special reference to selected immune parameters].

In children with a glomerulonephritis the immune laboratory parameters used by us showed deviations from the norm which are necessary to be pursued. This particularly concerns the differentiation of B- and T-cells, the determination of the subpopulations of the T-cells, furthermore also the control of the serum-IgM as well as the investigation of complement and C-factors 3 and 4, respectively. The laboratory methods mentioned deserve to be compared with and related to clinical, paraclinical and renal bioptic data of the GN-patients. Such correlations promise deeper insights into the pathogenic connections of certain forms of glomerulonephritis and possibly also as statement concerning the control of therapy.

Child↗
PubMed1986

[In vitro sensitivity of T lymphocytes to theophylline in healthy adults and patients following cadaver kidney allotransplantation].

In the peripheral blood of healthy adults the number of theophylline-resistant T-lymphocytes (T-res) is 51 +/- 4% and 1,161 +/- 326/microliter, respectively, and the number of theophyllins-sensitive 11 +/- 2% and 252 +/- 95/microliters. The membrane markers show a heterogeneous distribution. The quotient from T-res/T-sens is 4.9 +/- 1.3. Within the T-sens 14% are CD4+ and 30% CD8+, 29% carry Fc-IgC and 34% Fc-IgM-receptors. Thus the T-res in their netto-function were helper cells and the T-sens suppressor/cytotox cells. Before the transplantation the preoperative ratio of the two subpopulation is significantly diminished (Q = 3.66 +/- 1.53), however, prognostic statements cannot be deduced from this. Activations of the immune system (rejection crises, cytomegalovirus infections) are accompanied by significant diminutions of the T-sens, whereby the T-res/T-sens-Quotient increases. Thus they are unequivocally included into immunoregulatory processes.

Adolescent↗