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Biomedical subjects

K Kiefer

Publications and source records attributed to K Kiefer.

5 recordsLinked to original sources
PubMed2003

[Dissociative stupor as a postoperative consequence of general anesthesia].

A 31-year-old woman failed to awaken after an uneventful general anesthesia (propofol, alfentanil and 65% N2O in oxygen) for laparoscopic resection of an ovarian cyst. After the operation she was extubated and vital signs were stable. However, the patient remained unresponsive even to painful stimuli for about 2 h. Just before we performed a computed tomogram of the brain to exclude a cerebral lesion we noticed that she blinked. We hypothesized that unconsciousness was due to a dissociative stupor. After administration of sublingual lorazepam the patient woke up promptly and was alert and normal for the rest of the hospital stay. In conclusion, after exclusion of a pharmacological or organic cause for postoperative unconsciousness, dissociative stupor may be a reason for apparent coma after general anesthesia.

Adult↗
PubMed2003

Insulin-like growth factor (IGF)-1 and IGF binding protein-1 and -3 in the follicular fluid of infertile patients with endometriosis.

BACKGROUND: Endometriosis is associated with pituitary-ovarian axis dysfunction. The study of the follicular fluid in patients with endometriosis is important to elucidate the pathophysiological mechanism of this disease. The objective of this present paper was to analyse the dosages of insulin-like growth factor-1 (IGF-1) and IGF binding protein-1 and 3 (IGFBP-1 and IGFBP-3) in the follicular fluid environment of infertile patients with endometriosis. METHODS: A total of 41 infertile patients undergoing IVF between January 1999 and January 2000 participated in the cross-sectional prospective study. Patients were divided into three groups: group I, minimal/mild endometriosis (n = 12); group II, moderate/severe endometriosis (n = 10); and group III, tubal obstruction (n = 19). The ultra-short protocol was used in association with recombinant FSH for ovulation induction. Follicular fluid analysis was performed using radioimmunoassay with specific kits. RESULTS: Follicular fluid IGF-1 and IGFBP-3 levels were not significantly different among the groups; however, follicular fluid IGFBP-1 levels were lower in those patients with moderate/severe endometriosis (P < 0.05). Comparison of ovulation induction time, number of recombinant FSH units, number of follicles, oocytes and embryos, and fertilization and gestation/cycle rates showed non-significant differences. CONCLUSION: Infertile patients with moderate/severe endometriosis, which is associated with ovulatory dysfunction, presented lower levels of IGFBP-1 in the follicular fluid when undergoing IVF.

Adult↗
PubMed1980

[Recurrencies in oropharyngeal, hypopharyngeal and supraglottic squamous-cell carcinomas (author's transl)].

80 patients with recurrent carcinomas of the oropharynx, hypopharynx and supraglottis were examined. Average recurrency occured after 15,1 months. 10 patients showed first and 3 patients second recurrent carcinomas on the mucous membranes of the upper respiratory tract. All the recurrencies were located distant from the primary tumor site, within the irradiation field and most of the times contralaterally. Lymphatic vessel damage and inversion of the regular lymphatic drainage are discussed for their etiological role.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

[Control of infection using a screening system].

A simple system of infection control and the results of the first year of use are reported on. In comparison with a prospective control system is proved that even a simple questionnaire was not answered correctly by the doctors, nevertheless the relevant wound infections could be found out.

Cross Infection↗