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Biomedical subjects

K Killebrew

Publications and source records attributed to K Killebrew.

6 recordsLinked to original sources
PubMed1983

Complications of metrizamide myelography.

Adverse neurobehavioral reactions have not been emphasized as a complication of metrizamide myelography. We encountered six such reactions in approximately 250 metrizamide myelograms. All reactions followed either cervical myelography or panmyelography via lumbar puncture. We also treated a single case of tonic-clonic seizure after intracranial spill of metrizamide in a patient without a history of seizure disorder, and a case of myoclonus following a thoracic metrizamide myelogram that showed a highgrade block. Metrizamide should not be used if an intrathecal block is suspected, or if the location to be studied makes intracranial spill difficult to avoid.

Adult↗
PubMed1983

Metastatic renal cell carcinoma mimicking a meningioma.

We report a patient with renal cell carcinoma metastatic to the left trigone, which mimicked an intraventricular meningioma. The metastasis was recognized 1.3 years after removal of the primary tumor, a longer disease-free interval than any previously reported cases with brain metastases of renal cell carcinoma. The patient is now free of disease of years after resection and 17 years after the discovery of the primary tumor. Metastatic disease should be considered in all patients with prior resection of renal cell carcinoma who experience the onset of neurological disease, even after a prolonged disease-free interval. Long term survival is observed after the resection of solitary metastases, particularly if these appear after a prolonged disease-free interval.

Adenocarcinoma↗
PubMed1979

Computed tomography and spinal dysraphism: clinical and phantom studies.

Two cases illustrating the value of CT in the assessment of spinal dysraphic tissue are presented. In one case, the configuration and origins of two osseous diastematomyelic spurs were shown well; in the second case, the CT recognition of a sacral lipoma led to air myelographic confirmation of the tumor and tethered cord. CT phantom studies indicated that dysraphic tissues, such as fat, cartilage, and fibrous tissue, are better identified and quantitated in the spinal canal when surrounded by air. Varying degrees of image degradation occur with water (simulating CSF) or metrizamide.

Adult↗
PubMed1979

Metastasis of a rectal carcinoid to the posterior fossa.

We report the metastasis of a rectal carcinoid to the dura mater of the posterior fossa. The clinical presentation was unusual because of a 10-year latent period between resection of the primary rectal tumor and symptoms and signs of the posterior fossa metastasis; the radiological findings were atypical of a metastasis. Gastrointestinal carcinoids, apudomas, and the concept of the APUD endocrine cell family are reviewed.

APUD Cells↗
PubMed1975

Multicentric reticulohistiocytosis (lipoid dermato-arthritis). An erosive polyarthritis with distinctive clinical, roentgenographic and pathologic features.

Detailed analysis of the progressive roentgenographic changes found in complete serial skeletal surveys of 2 men with multicentric reticulohistiocytosis (MR) have been correlated with pathologic finds and compared to features preivously reported. The lesions of MR predominate in skin and synovium and result in the following characteristic features: (1) sharply circumscribed, rapidly progressive, strikingly bilaterally symmetric erosions spreading from joint margins to articular surfaces; (2) interphalangeal joint predominance; (3) early and severe atlanto-axial involvement; (4) disproportion between severity of joint destruction and mildness of symptoms; (5) absent or minimal periosteal reaction; (6) absent or disproportionately mild osteoporosis compared to the severity of erosions; and (7) prominent, uncalcified soft tissue nodules. Since arthritis often precedes cutaneous manifestations, careful roentgenologic evaluation may play key role in early diagnosis.

Adult↗