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Biomedical subjects

K Kiriakou

Publications and source records attributed to K Kiriakou.

17 recordsLinked to original sources

Noise sources and levels in the Evgenidion Hospital intensive care unit.

Noise sources and levels were evaluated in a six-bed intensive care unit (ICU) in Athens, Greece. Ten patients (six males, four females) completed specifically designed questionnaires, and at the same time nine 8-h sound measuring sessions took place. A Bruel and Kjaer 2231 sound-meter was used on the decibel-A scale combined with observation. Human activity, operating equipment and construction engineering of the hospital building were identified as sources of noise. Noise levels were elevated [LEQ = 60.3-67.4 dB(A)]. No reliable information was obtained from the questionnaires. ICU noise levels were higher by 27 dB(A) than recommended hospitals levels. To counteract noise pollution in ICUs, staff awareness and sensitivity are needed.

Environmental Health↗

[Perforation of the urinary bladder with retroperitoneal abscess formation and septic shock following diagnostic curettage].

A case of perforation of the urinary bladder is presented which occurred occasionally a diagnostic curettage. At admission there was a severe septic shock. After intensive treatment the diagnosis of perforation of urinary bladder was made by intravenous urography and cystography. Laparotomy with closure of the perforation, lavage of abdomen and drainage of the pouch of Douglas made a total recovery.

Abscess↗

[Fibrothecoma of the ovary with typical Meigs syndrome and tumorous cachexia].

A case of a big fibrothecoma of the right ovary is reported. A women 49 years of age was admitted in a bad general situation with anemia, ascites, hydrothorax and weight loss. On operation the tumor looked like malignant one. Both the ovaries were excised. The pathological examination showed a fibrothecoma of the ovary with no signs of malignancy. The postoperative period was uneventfull and the patient is in a good condition 7 months after operation.

Cachexia↗

Short left coronary artery trunk as a risk factor in the development of coronary atherosclerosis. Pathological study.

The relation between the length of the main left coronary artery and the degree of atherosclerosis in its branches was studied by postmortem examination in 204 subjects aged 20 to 90 years. The findings suggest that in cases with a short main left coronary artery the atherosclerotic lesions in the anterior descending and circumflex branches appear earlier, progress faster at higher levels of severity, and lead more frequently to myocardial infarction, than in cases with a long left coronary artery trunk. In cases over the age of 50 years, where disease is expected to have developed, it was shown that the degree of atherosclerosis in the left anterior descending and circumflex branches was inversely related to the length of the main left coronary artery. The correlation coefficients were -0-527 and -0-428, respectively, and in either case a test for zero correlations was significant (P less than 0-001). The possible changes in the haemodynamic and mechanical conditions associated with the variations of the anatomical pattern of the coronary arteries and their influence in the development of atherosclerosis are discussed. It is suggested that the length of the main left coronary artery is a congenital anatomical and possibly hereditary factor influencing the rate of development of atherosclerosis in the branches of the main left coronary artery.

Adult↗

Prognostic variables in greek patients with stage II breast cancer: a Hellenic Cooperative Oncology Group study.

The independent effects of several patient, tumor and treatment-related prognostic factors on relapse-free survival (RFS) and overall survival (OS) were assessed by Cox multivariate regression analysis in 988 Greek patients with stage II breast cancer. At a median follow-up time of 83 (range 3.3-131+) months and after the evaluation of all patients together, the number of positive axillary nodes (p < 0.0001), tumor size (p = 0.0024) and tumor grade (p = 0.0008) were identified as significant prognostic factors for RFS. Also, the number of positive nodes (p < 0.0001), tumor size (p = 0.0002) and ER status (p = 0.0001) were found to be significant for OS. These short-term prognostic variables are similar to those reported for this group of patients in other European countries and in the USA.

Adult↗