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Biomedical subjects

K Kitahara

Publications and source records attributed to K Kitahara.

At least 19 recordsLinked to original sources
PubMed1992

Establishing a diagnosis of adrenal metastasis from hepatocellular carcinoma by 99mTc-PMT hepatobiliary scintigraphy.

A 69-year-old woman was diagnosed as having hepatocellular carcinoma (HCC) with liver cirrhosis in October, 1984 and treated by transcatheter arterial embolization (TAE). In June, 1990 she was found to have a huge mass in the left hypochondrium which ultrasonography and computed tomography (CT) scan revealed to be a lett adrenal mass. A 99mTc pyridoxyl-5-methyl tryptophan (99mTC-PMT) hepatobiliary scintigraphy was positive and confirmed metastatic HCC. Although the adrenal mass was large, the HCC itself was controlled well with TAE. The adrenal mass was removed surgically in July, 1990 and the histological findings were compatible with HCC metastasized to the adrenal gland.

Adrenal Gland Neoplasms↗
PubMed1992

Blood pressure changes following extracorporeal shock wave lithotripsy for urolithiasis.

Hypertension after extracorporeal shock wave lithotripsy (ESWL) has been a controversial subject. Changes in blood pressure were studied in 262 patients (mean age 47.8 years) 18.6 months after ESWL. According to World Health Organization criteria the number of patients who showed a decrease exceeded those who showed an increase in blood pressure. The patients who have been on antihypertensive therapy showed a significantly greater decrease in blood pressure than those without medication. Of 192 normotensive patients diastolic pressure increased 1.2 mm. Hg and 2 (1.0%) had hypertension 18.4 months after ESWL. Annualized increase in diastolic pressure and new onset of hypertension were calculated to be 0.78 mm. Hg and 0.65%, respectively. Significant elevation of diastolic pressure was noted in the patients who received a larger number of shock waves. Blood pressure should be carefully followed after ESWL especially in patients who have been treated by a greater number of shock waves.

Adult↗
PubMed1992

[Implantation of self-contained non-inflatable penile prosthesis in patients with organic impotence].

Between April, 1988 and August, 1990, the OmniPhase penile prosthesis, a non-inflatable self-contained penile prosthesis, was implanted in 34 patients, aged from 37 years to 79 years, averaging 54.2 years. The etiologies of the impotence were radical surgery for bladder cancer or rectal cancer in 17 patients, diabetes mellitus in 7 patients, vascular abnormality in 3 patients, spinal injury in 2 patients, penile disorders in 2 patients and others in 3 patients. Penile prosthesis was implanted by subcoronal incision under spinal or general anesthesia. Clinical results were evaluated 12 weeks after surgery. Thirty-two patients (94.1%) could have intercourse postoperatively. Eighteen patients (52.9%) were completely satisfied and 14 patients (41.2%) were satisfied, whereas one patient (2.9%) had no improvement and another patient (2.9%) deteriorated. There was no serious complication. However, prosthesis was explanted because of skin erosion in one patient. Pain, which lasted for more than 10 days, was seen in 3 patients (8.8%), penile edema in 11 patients (32.4%), and acute epididymitis in one patient. The obtained results showed that implantation of OmniPhase penile prosthesis is a safe and useful procedure for treatment of organic impotence.

Adult↗
PubMed1992

[Auto recording system for the Goldmann perimeter].

In order to develop a method for converting the Goldmann perimeter data directly for computer storage and evaluation, a recording instrument was designed as a modification of the Goldmann perimeter. By installing the two potentiometers on the pantographic arm and electrical switches, the position of the test target and the setting of the four levers which defines the size and the brightness of the test target were transferred directly to the computer. Accuracy of this recording system is better than 1.3 degree over the entire surface of the chart. This system will make it possible to easily follow changes in the visual fields of the same patient, i.e. shape change, numerical value.

Humans↗
PubMed1992

[A dissociation of thresholds between Goldmann kinetic perimetry and high-pass resolution perimetry in retinitis pigmentosa].

The authors studied the differences between the automated static perimetry of high-pass resolution perimeter (HRP) and the kinetic perimetry of the Goldmann perimeter in 12 patients with retinitis pigmentosa. In a total of 10 eyes of 6 patients, we found 19 quadrants in which the patients were not able to recognize the largest ring target even when the target was within the isopter of the Goldmann perimetry. Also, there were 10 quadrants in which the largest target was not recognized in a total of 6 eyes of 4 patients even though their visual field showed symmetrical isopter in upper and lower or right and left quadrants in the Goldmann perimetry. As a result, it was suggested that the causes of the dissocation were a greater decrease in sensitivity for the low spatial frequency target than the high spatial frequency target and/or a greater decrease in resolution sensitivity than light sensitivity in retinitis pigmentosa.

Adolescent↗
PubMed1992

Nonfamilial and unusual cases of Leber's hereditary optic neuropathy identified by mitochondrial DNA analysis.

Peripheral blood mitochondrial DNA (mtDNA) samples from 11 patients with acute optic neuritis or insidious optic atrophy were examined for the mutation at nt 11778 and nt 3460 in polymerase chain reaction products. The mtDNA mutation at nt 11778 was evident in 8 cases, which led to a definite diagnosis of Leber's hereditary optic neuropathy (LHON); 4 of the cases were familial and the remaining 4 cases were nonfamilial. None of the 11 patients showed the nt 3460 mutation. The symptoms and signs were variable among the LHON cases with nt 11778 mutation. Assessment of mtDNA provides a useful diagnostic aid for clinically undefined, seemingly nonfamilial or atypical cases of Leber's hereditary optic neuropathy, particularly in bilateral, insidious optic nerve disease in early childhood.

Acute Disease↗
PubMed1991

[Thallium-201 lung uptake in patients with chronic phase of myocardial infarction].

To study pathophysiological significance of Tl-201 lung uptake in coronary artery disease Tl-201 lung uptake was studied in 159 patients with chronic phase of myocardial infarction. Tl-201 lung uptake images were collected after rest Tl-201 myocardial imaging. Tl-201 lung uptake was estimated by comparing maximal lung counts with maximal myocardial counts (thallium lung heart ratio: LHR). Good correlation between LHR and mean pulmonary artery wedge pressure (mPw) and between LHR and left ventricular ejection fraction (EF) were obtained, (mPw = 2.7 +/- 10.5 LHR r = 0.52 n = 102, p less than 0.001, EF = 84.9-52.2 LHR r = -0.61 n = 159, p less than 0.001). It was noted that Tl-201 did not accumulate uniformly through the lung field and usually maximal Tl-201 lung uptake was noted at the basal zone of the right lung. Tl-201 lung uptake in the upper zone of the right lung increased in proportion to the hemodynamic deterioration. Interesting differences were noted between Tl-201 lung uptake in patients with chronic phase of myocardial infarction and that in patients with acute phase of myocardial infarction. The prognosis and clinical status of patients with markedly increased Tl-201 lung uptake (LHR greater than 0.8) in chronic phase were more excellent than the patients with similar Tl-201 lung uptake in acute phase. Hemodynamic parameters in patients with markedly increased Tl-201 lung uptake (LHR greater than or equal to 0.8) in chronic phase were significantly better than in those in acute phase.(ABSTRACT TRUNCATED AT 250 WORDS)

Chronic Disease↗
PubMed1990

[Studies on O'Leary's plaque control record in initial periodontal treatment. 1. Relation between PCR and different brushing methods in 1982-1986].

The purpose of this study was to investigate the effects of different methods of brushing on plaque removal, using O'Leary's plaque Control Record during initial preparation. The results were as follows: 1. There were many 40-50 year-old patients and they showed a 63.0 percent first visit Plaque Control Record average. 2. Many of the patients entering the clinic had periodontal disease in mild stages. 3. In most cases the toothbrushing methods were the Rolling method and the Modified Stillman's method. Of the patients, 73.5% achieved Plaque Control scores at the 20 percent level. 4. Of the patients who had achieved a Plaque Control Record at the 20 percent level, half of the patients instructed to brush using the Rolling method had developed moderate forms of periodontal diseases, and half of the patients instructed to use the Modified Stillman's method had developed mild forms of periodontal disease. There is a close relationship between toothbrushing methods and the progression of diseases, and this shows that Plaque removal methods should be controlled.

Adult↗
PubMed1990

[Treatment in 50 cases of transitional cell carcinoma in renal pelvis and ureter].

A total of 50 cases of primary tumors in the renal pelvis and ureter were treated in Tokyo University Branch Hospital (20 cases in 1966-1982) and in Tranomon Hospital (30 cases in 1977-1987). They were composed of 42 men and 8 women (5.3:1) with a mean age of 61 years. 31 patients suffered from renal pelvic tumors, 15 ureteral tumors and 4 tumors in both sites. The tumors were located in the left side in 33 cases, right in 16, and both sides in 1.86% of patients showed gross hematuria. The findings on IVP were filling defect (42%) and nonvisualization (33%). Positive urine cytology was obtained in 12 of 25 cases (48%). Surgery was performed in 47 cases. The remaining 3 cases were with advanced diseases. The surgeries were total nephroureterectomy plus ipsilateral retroperitoneal lymph node dissection in 26 cases, total nephroureterectomy without node dissection in 7, total nephroureterectomy and total cystectomy in 3, nephrectomy in 9, partial nephrectomy in 1 and segmental excision of ureter with ureteroureterostomy in one. Histologically, all tumors were transitional cell carcinoma. Over-all survival rates (Kaplan-Meier's method) of the operated patients at 1, 3, 5 years were 84.2%, 73.1% and 69.4%, respectively. The stage and grade of the tumors affected the prognosis. N factor at lymph node dissection was the most determining factor of prognosis. 3 advanced cases who did not receive surgery for primary site were treated with 5FU in 2, and with CAP in 1.2 of them died of the disease within 1 year after diagnosis, one patient was lost in follow up.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1990

[The use of the panel D-15 test in estimating the convergence points for deuteranopia].

In order to study the deuteranopic convergence points we compared the patterns of the simulated panel D-15 test with the actual data from 73 cases of deuteranopia. It was found that 39 of the 73 cases matched one of the four simulation patterns perfectly while another 25 cases showed similar patterns. Of the 64 cases, 9 cases matched the simulated pattern obtained when the x chromaticity coordinates were between 1.1810 and 1.4319, 42 cases when they were between 1.4320 and 2.2588, 7 cases when they were between 2.2589 and 3.6255 and 6 cases when they were between 3.6256 and 4.6572. These results confirm that there are significant individual differences in the convergence points of deuteranopes and support the theory that the confusion lines meet at a specific point rather than running parallel.

Adolescent↗
PubMed1989

[New color imaging of [99mTc]-pyrophosphate and [201Tl]-chloride dual isotope single photon emission computed tomography in acute myocarditis].

[99mTc]-pyrophosphate (PYP) and [201Tl]-chloride dual isotope single photon emission computed tomography (SPECT) is now available to detect the site and extent of acute myocardial infarction. In inflammatory myocardial disease, [99mTc]PYP makes hot image on damaged area. We performed dual isotope SPECT of [99mTc]PYP and [201Tl]Cl in two patients with acute myocarditis and severe rhythm disturbance to evaluate the severity of inflammation. Myocardial damage was estimated by [201Tl] perfusion coloring blue and myocardial inflammation was estimated by [99mTc]PYP uptake coloring red. The overlap display of both images made it clear to detect spatial extent of myocardial inflammation. Using this technique, we expect to estimate the severity of myocarditis and to make a decision of therapeutic plan.

Acute Disease↗
PubMed1989

[Dental application of imaging information. Evaluation of optimum tube voltages].

The subjective contrast including the density component of radiograph as well was aimed at. In relation to the intraoral radiographs (18 cases) of the left first molar of the mandible and its surrounding tissue taken using tube voltage of 60-90 kV, the radiographs were evaluated based on the mean of the extracted subjective contrast values, resulting in the following findings: 1. A tendency was observed in the enamel and dentine of the central portion of crown, for the mean of the extracted subjective contrast values using tube voltage of 70 kV to be lower than that with 60 kV. 2. A tendency was found in the dentine on the cement side of the mesial and distal cervical portion and the periodontal membrane space of the cervical portion, for the mean of the extracted subjective contrast values to generally become larger as the tube voltage was increased. 3. A tendency was recognized in the alveolar lamina dura of the mesial and distal marginal alveolar portion, for the mean of the extracted subjective contrast values to become larger as the tube voltage was increased. From intraoral radiographs of teeth, the findings mentioned above have proved that good radiographs will be created using a tube voltage of 70 kV for enamel and dentine, and using 60 kV for dentine and cement in the area of the cervical portion or in case of the periodontal tissue.

Humans↗
PubMed1989

[Theoretical patterns of the panel D-15 test in congenital dichromatic color vision defects].

In order to study the theoretical patterns of the panel D-15 test for congenital dichromatic color vision defects, the spectral reflectance for the 16 color caps of the panel D-15 test was measured with a spectro-photometer. Then, the chromaticity-coordinates of each color cap were calculated using the spectral distribution of standard illuminant C. The theoretical patterns of the panel D-15 test for dichromats were obtained based on the confusion lines. For this procedure, the slope of the line between the color cap and the convergence point on the CIE chromaticity diagram was obtained first. Then, the order of the arrangement was decided starting with the slope having the smallest cap number and continuing progressively. For the chromaticity coordinates of the convergence points the following values were used; x = 0.7465, y = 0.2535 for protanopia, x = 1.08, y = -0.08, x = 1.40, y = -0.40, and x = 1.70, y = -0.70 for deuteranopia, and x = 0.171, y = 0.000 for tritanopia. The results show a very clear similarity between the orientation axis obtained by simulation and the actual data. Therefore, it was confirmed that dichromats arrange the color caps in the order of the slope of the line between the color cap and the convergence point, when performing the panel D-15 test. Furthermore, it was suggested that the patterns of the panel D-15 test differ by the convergence points among dichromats even of the same type.

Color Perception↗
PubMed1989

[Theoretical patterns of the panel D-15 test in congenital red-green dichromats as a function of the chromaticity coordinate of the convergence points].

In order to determine whether or not the patterns of the panel D-15 test for congenital red-green dichromats change when the convergence point is changed, a simulation experiment was attempted assuming that dichromats arrange the color caps in the order of the slope of the line between the chromaticity coordinates of the color cap and the convergence point. For this procedure, chromaticity coordinates of the color cap were calculated using both the spectral distribution of standard illuminant C and the daylight fluorescent lamp (Toshiba-EDL). For this prediction, the chromaticity coordinates of the convergence points were changed according to y = 1-x. The results show several different patterns for both protanopia and deuteranopia under both illuminants. The range of the x chromaticity coordinates common to both illuminants was 0.6868 to 0.8552 when the protanopic patterns were obtained, while the range of the x chromaticity coordinates common to both illuminants for deuteranopic patterns was 1.0878 to infinity and minus infinity to -1.8153. As a result, it was suggested that the patterns of the panel D-15 test for red-green dichromats change according to the convergence points. Therefore, it was considered that this test cannot be used as a dependable measurement for color discrimination ability in cases showing dichromatic patterns.

Color Perception↗
PubMed1986

[Arteritis and fatty degeneration of the spermatic cord resembling periarteritis nodosa: a case report].

A 23-year old male was admitted to our hospital because of swelling of the left scrotum for one month without any particular past history. Blood count, chemistry, urinalysis, chest X-ray and electrocardiogram revealed normal findings. Scrotal exploration was performed. A soft, dumbbell-like tumor enveloped in a thin membrane was found above the left testis. Pathology revealed fibrinous exudation and fibrinoid necrosis in the whole vessel wall indicating resemblance to the panarteritis in periarteritis nodosa. Some granulomatous lesions with many histiocytes were also noted around these arteries. The findings suggested that a inflammation like periarteritis nodosa had occurred at the spermatic cord and subsequently developed into fatty degeneration in the surroundings. Since local periarteritis nodosa-like lesion may progress to systematic disease, further observation is mandatory for this case.

Adult↗