PubMed Health⌕ Search

Biomedical subjects

K Kitamura

Publications and source records attributed to K Kitamura.

At least 1,297 records · Page 72Linked to original sources
PubMed1981

[Cineangiographical and histopathological studies on hypertrophic myocardial disease with giant negative T wave (author's transl)].

A total of 19 patients consisted of 10 cases with hypertrophic cardiomyopathy (HCM), 6 with hypertensive heart disease (HHD) and 3 with professional bicycle racers with myocardial hypertrophy, showing giant negative T waves greater than 10 mm in precordial leads (GNT-group) was examined by catheterization, cineangiography and endomyocardial biopsy. Fourteen patients of myocardial hypertrophy consisted of 5 cases with HCM, 4 with HHD and 4 with professional bicycle racers without giant negative T (non-GNT-group) were selected as the control. The average of mid-ventricular wall thickness (Tm = 17.4 +/- 4.6 mm) and that of apical wall thickness (Ta = 18.5 +/- 3.6 mm) obtained from the left ventriculogram in GNT group were significantly greater than those in non-GNT group. The average of the apical hypertrophic index (Ta/Tm = 1.1 +/- 0.3) was also greater than that in non-GNT group. For the evaluation of hypertrophy of the papillary muscles, pattern of the hypertrophy was divided into 2 types by the feature of the left ventriculogram in systolic phase of right anterior oblique view, i.e., normal to moderate (type I) and severe (type II). In GNT group, 79% of patients belonged to the type II, whereas 71% of patients in non-GNT group belonged to type I. Histopathologically, the hypertrophy of heart muscle cells in GNT group was higher grade than in non-GNT group. Disarray of the muscle cells and myocardial fibrosis was not so prominent in GNT group. It was concluded that the mode of hypertrophy in GNT group was characterized by the existence of papillary muscle hypertrophy and had similarity to the hypertrophy of known etiologies such as mechanically overloaded myocardium which suggested to the secondary heart muscle diseases.

Adult↗
PubMed1981

[Intraventricular extravasation of contrast media through primary intraventricular hemorrhage (author's transl)].

A 22-year-old woman was admitted following the sudden onset of severe headache and loss of consciousness. On admission, she was delirious with nuchal rigidity. A lumbar puncture showed bloody spinal fluid. Laboratory studies revealed no abnormalities. Her consciousness state became clear 2 days after the attack. Computerized tomography taken 7 days after the attack revealed intraventricular hemorrhage in the right trigonum. Emergent right carotid angiography was performed. The intraventricular extravasation of contrast media was shown in the region of the right trigonum. One hour after the angiography, she was semicomatose with left flaccid hemiplegia. Reexamination of computerized tomography revealed diffuse intraventricular hemorrhage and periventricular intracerebral hematoma in the right parieto-temporal lobe. Emergent operation was performed and intracerebral hematoma was extirpated. Good postoperative results were obtained after ventriculoperitoneal shunting 46 days after removal of the hematoma. In our review of the literature, intraventricular extravasation of contrast media through primary intraventricular hemorrhage has not been reported.U

Adult↗
PubMed1981

[Head injury in children--with special reference to CT findings (author's transl)].

Findings of computerized tomography (CT) in 183 cases of head injury in children were investigated with special reference to CT findings of mild head injury. As was expected, CT findings of mild head injury fell within the normal range, in almost all cases. However, abnormal findings were noticed in 4 out of 34 cases (12%) in acute stage and 7 out of 76 cases (9%) in chronic stage. They were 3 cases of localized low density area in acute stage and 6 cases of mild cerebral atrophy in chronic stage, etc. There were some cases of mild head injury in which CT findings were normal while EEG examination revealed abnormality. Also in some cases, x-ray study demonstrated linear skull fracture which CT failed to show. These conventional techniques could be still remained as useful adjunct aid in diagnosis of head injury. CT findings of cases of cerebral contusion in their acute stage were divided as follows; normal, low density, small ventricle and ventricular and/or cisternal hemorrhage, frequency of incidence being 38, 17, 22, 11% respectively. These findings were invariably converted to cerebral atrophy from 10 days to 2 months after the impacts. In the cases with intracranial hematoma revealed by CT, only 32% of them showed clinical signs of Araki's type IV in their acute stage and 63% of them showed no neurological defects, that is Araki's type I & II. A case of extreme diffuse cerebral atrophy which followed acute subdural hematoma caused by tear of bridging veins without cortical contusion was presented.

Adolescent↗
PubMed1981

[Cerebral arterial occlusive disease in children -- clinical aspects and surgical treatment (author's transl)].

In the present study the pathology and treatment of occlusion of cerebral arteries in children were investigated in an attempt to find out an approach to the surgical treatment of cerebral arterial occlusive disease of childhood. We had a total of 55 children with cerebrovascular disorders seen at our Institute during the past 11 years. In this series there were 19 cases of cerebral arterial occlusive disease. The causes in 15 cases of cerebral arterial occlusive disease except for moyamoya disease were heart disease in 7 cases, trauma in 2 cases and unknown in 6 cases. The cerebral arterial occlusive disease had its onset at the age of less than 6 years in 12 of 15 cases. The disease began with hemiplegia of sudden onset. The disease onset was also attended frequently by a convulsive seizure, which distinguishes the condition from that in adults. In 10 of all 15 lesions the site of occlusion was in the distribution of the middle cerebral artery. One case in which there was occlusion of the basilar artery occurring in association with trauma was described in detail. In one instance the treatment consisted of STA-MCA anastomosis. Paroxysmal black out attacks, which had been of frequent occurrence in addition to hemiplegia were relieved postoperatively. In our opinion, STA-MCA anastomosis for cerebral arterial occlusive disease in children should be considered to be indicated only when 1) cerebral angiographic evidence of occlusion or stenosis of a trunk of cerebral artery is still present after the acute stage or 2) no extensive low density area is demonstrable on CT scan. Surgery is generally less indicated in those instances in which the occlusion is due to embolism. However since abscess may arise from such an arterial lesion, surgery should be considered, or at least its feasibility be evaluated, whenever 1) the underlying cardiac pathology well permits surgical intervention and 2) half a year has passed since an initial attack.

Adolescent↗
PubMed1981

[A huge frontal sinus pyocele extending into the cerebral falx - a case report (author's transl)].

A 50-year-old male was admitted to us presenting a bulging of 5 X 6 cm in size on the forehead. His general condition was excellent and neurological status was normal. The mass in the forehead was soft and showed a fluctuation. On the plain skull films, a lobulated bone defect of 5 X 4 cm in size was noticed in the frontal bone and the frontal sinus completely disappeared. Carotid angiograms revealed posterior displacement of the supraclinoid portion of the internal carotid arteries and the proximal part of the anterior cerebral arteries, and elevation and posterior displacement of both frontopolar arteries. Capillary and venous phase of the carotid angiograms demonstrated an avascular area in the frontal cranial fossa. Branches of the anterior cerebral artery were stretched and displace surrounding the avascular mass. These angiographic findings indicated a huge avascular both frontal lobes posterolaterally. CT scanning revealed a large isodensity mass and the periphery of the mass was enhanced in a ring-like fashion with contrast medium. The mass protruded as a subcutaneous mass through the defect of the frontal bone. The content of the mass was surgically evacuated. The mass was a pyocele containing thick yellowish purulent fluid. It arose from the frontal sinus and extended into the anterior cranial fossa through the destroyed posterior wall of the sinus to separate the falx into two leaves of the dura mater and displace both frontal lobes laterally and posteriorly. Extension of the frontal sinus mucocele and pyocele to the anterior cranial fossa was discussed.

Cerebral Angiography↗
PubMed1981

[Three cases of cystic neurinoma arising from the upper cervical nerve roots and extending into the posterior cranial fossa (author's transl)].

Three cases of cystic neurinoma arising from the upper cervical spinal nerve roots and extending to the posterior cranial fossa through the foramen magnum were reported. Case 1 was a 52-year-old female presenting marked bilateral papilledema, hyperactive right knee jerk, left positive Gordon reflex and trunkal ataxia. The mass was mostly cystic and arose from the left 1st cervical nerve root. It extended to the posterior fossa, occupied the cerebello-medullary cistern and displaced the left cerebellar hemisphere posteriorly and superiorly. Case 2 was a 39-year-old male presenting marked bilateral papilledema, neck stiffness, dysfunction of the right 7, 9, 10 and 11th cranial nerves, gaze nystagmus, Horner's syndrome, right limb ataxia, and ataxic gait. The mass was totally cystic containing yellowish fluid and was growing from the right 2nd cervical spinal nerve root. The mass extended to the posterior cranial fossa up to the right cerebello-pontine angle and compressed the medulla oblongata, upper cervical cord and 7th through 11th cranial nerves on the right side. Case 3 was a 66-year-old male presenting marked bilateral papilledema, gaze nystagmus, left hemiparesis, bilateral hyperactive deep tendon reflexes, numbness of the left fingers and ataxic gait. CT scanning revealed in the midline of the posterior cranial fossa a low density mass which was enhanced in a ring-like fashion. Vertebral angiograms showed an avascular mass displacing the PICAs upwards and elongating its cranial loops antero-posteriorly. The mass was totally cystic, arose from the left 2nd cervical spinal nerve root, extended to the posterior cranial fossa and occupied the cisterna magna and vallecula. Foramen magnum syndrome was discussed and the symptoms and signs presented in these three cases were compared with those presented by foramen magnum meningioma in other reports.

Adult↗
PubMed1980

Neuritogenic activity of peripheral nerve myelin proteins in Lewis rats.

The neuritogenic activity of human peripheral nerve myelin proteins in Lewis rats was examined. Experimental allergic neuritis (EAN) was induced by human myelin fraction in all Lewis rats examined. Purified human P2 protein induced mild but definite EAN. None of purified P0 protein, total myelin lipids, gangliosides and cerebrosides induced EAN. Addition of total myelin lipids or gangliosides to the P2 protein did not enhance the neuritogenicity of the P2 protein. Bovine P2 protein, which was inactive in rabbits and guinea pigs, showed considerable neuritogenicity in Lewis rats. We postulate that induction of EAN depends both on the species of host animal and the source of antigen.

Animals↗
PubMed1980

A genetic aspect of chromatin proteins of human brain tumors.

Electrophoretic analysis of chromatin proteins was performed on rat and human tissues. Species and organ specific patterns were demonstrated in them. Twenty cases of human brain tumours were also analyzed and each tumor had typical phoretic patterns of chromatin. Proteins obtained from histologically similar tumors display similar electrophoretic patterns. As to the ratio of chromatin protein to DNA, no apparent differences between benign and malignant human brain tumors were observed.

Animals↗