Single dose comparison of torasemide and furosemide in patients with advanced renal failure.
In a comparative study on the fluid and electrolyte excretion of 90 patients with chronic renal failure (serum creatinine greater than or equal to 3.0 mg/dl) 100 and 200 mg torasemide (1-isopropyl-3- ([4-(3-methyl-phenylamino)pyridine]-3-sulfonyl)urea) vs. 100 and 200 mg furosemide were administered intravenously. A long-acting salidiuretic effect was demonstrated for torasemide. Torasemide can thus be categorized as a high-ceiling, long-acting diuretic. Tolerance of both diuretics was comparable.
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