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Biomedical subjects

K Kleinmann

Publications and source records attributed to K Kleinmann.

10 recordsLinked to original sources

Controlled study of the impact of educational home visits by pharmacists to high-risk older patients.

Lack of information about medications coupled with high rates of utilization complicates compliance with medication regimens and increases the risk of adverse effects among older adults. We undertook a study of the efficacy of community-based interventions by pharmacists in a randomly-allocated one-half of a sample of 284 older adults considered to be at high risk for medication-related problems. Information and attitudes towards prescription and over-the-counter medications did not differ significantly between the intervention and comparison groups, either before or after the pharmacist interventions. However, visits to physicians were significantly less in the intervention group, suggesting an important if unexpected impact on health-related behavior.

Aged

Semiquantitative test for iodine vapor above "complexed" iodine solutions.

A test to determine the extent to which free iodine exists in the vapor phase above the surface of "complexed iodine" solutions is described. The procedure is based on the qualitative starch-iodine test. The results can be related to the degree of complexation occurring between the polymer used in the preparation and iodine. Four products were tested: nonylphenoxypoly ethanol-iodine complex; polyvinyl pyrrolidine-iodine complex; popoxamer-iodine complex; and nonylphenoxypoly ethanol and polyvinyl pyrrolidone iodine complex. Free iodine in the vapor phase of the first product was detected in 90 minutes; the time for the other three was five days. For the tincture of iodine control, the time was 30 minutes.

Gases

Meal interference with antibiotics administered orally in hospitals.

A study of 132 hospitals in New York City was conducted to determine: (1) The usual drug administration and meal serving time schedules used; (2) if oral antibiotics recommended to be given on an empty stomach are actually administered with or near meals; and (3) who is responsible for establishing drug administration time schedules. A structured-disguised questionnaire was used and administered via telephone. Results revealed a wide variation of drug administration time schedules and meal serving times. Meal interference with oral antibiotic absorption was defined as a meal that is served less than one hour before or two hours after an oral antibiotic is scheduled to be administered. The incidence of meal interference ranged from 35 percent to 64 percent. The pharmacy and therapeutics committee, more often than any other group or individual (19.2 percent), was responsible for establishing drug administration times. A formal dosage schedule for orally administered antibiotics is recommended as an effort to reduce the incidence of meal interference with antibiotic absorption. Such a schedule developed at one hospital is presented.

Administration, Oral