[Acute interstitial nephritis caused by 5-aminosalicylic acid?].
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Biomedical subjects
Publications and source records attributed to K Krentz.
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Two cases are reported with polypoid changes of the corpus mucosa of the stomach. X-ray and endoscopic diagnosis was: gastric polyposis. On histological examination cystic changes of the mucosal glands could be detected. These cases were followed up for 7 years; no change occurred during this period until finally the "polyps" disappeared. Localization in the corpus area and easiness of endoscopic polypectomy, as well as the cystic pattern of the mucosa are typical for these "glandular cysts". This condition was unknown up to now or was not diagnosed correctly, this entity not having been delineated yet nosologically.
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From our endoscopic follow-up studies in 65 patients we are inclined to think that the various forms of erosive changes of the gastric mucosa represent different developmental stages of the same pathological process, in which the final stage may possibly be a hyperplasia of mucosal folds with gastro-intestinal loss of protein. A change into a genuine polyposis or even the development of a polypous carcinoma, as suggested by the information of Nakamura, was not observed by us, but the observation time so far has probably been too short for this anyway.
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