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Biomedical subjects

K Kudeva

Publications and source records attributed to K Kudeva.

4 recordsLinked to original sources

[Hemostatic disorders in patients with Schoenlein-Henoch syndrome].

Several indices of coagulation and fibrinolysis were studied in 54 patients suffering from Schönlein-Henoch disease. A significant prolongation of platelet aggregation was found in parallel with a decrease of AT III and plasminogen and an increase of the fibrin monomer complexes. Consequent to heparin treatment controlled by measurements of residual thrombin activity, the indices showed a trend towards normalization. The dynamic monitoring of the above indices can be used for an overall assessment of the heparin treatment.

Adult↗

[Immunological changes in Schönlein-Henoch patients].

The level of serum IgI, A, M, complement titre and circulation immune complexes were studied under clinical conditions of 17 patients with Schönlein-Henoch, active phase. The following changes were established as compared with the control, healthy subjects: four-times increased values of the circulating immune complexes, elevated IgA serum level, and IgG--to a lesser degree and reduced titre of the complement. Prognosis is more unfavourable in patients with extremely high values of the circulating immune complexes and complement consumption.

Adult↗